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1. flavones,
2. flavanones,
3. isoflavones,
• According to the oxidation status and saturation of the heterocyclic
ring, flavonoids are divided into several groups, which include
flavones
B
4. flavonols,
5. 3-deoxy flavonoids
6. anthocyaninsanthocyanins
Flavones comprise one of the largest groups, which are characterized by the
presence of a double bond between CC--22 andand CC--33, and the attachment of the B ring
to CC--22
A
Jan-SBBU
Ref. Nan Jiang, Plants 2016, 5(2), 27
Jan-SBBU
Occurrence of flavones
The various flavones that have been
reported in wood or bark of higher plants
are listed in Table
Type Structure (name) Genus, species
(family)
Location
(b=Bark, W=Wood, HW-Heart wood)
Simple flavones
• 5,6-dimethoxy Rutaceae B ‫وغيره‬ ‫مالٹا‬• 5,6-dimethoxy Rutaceae B ‫وغيره‬ ‫مالٹا‬
• 5,6,2'-trimethoxy -- B
• 5,7,3' ,4' -tetrahydroxy
(luteolin)
Rosaceae HW
C-Methyl flavones
• 5,7 -dihydroxy-6-C-methyl
• (strobochrysin)
Pinus (Pinaceae) HW
• 5-hydroxy-7 ,4' -dimethoxy-
6,8-di-Cmethyl
(eucalyptin)
Eucalyptus
(Myrtaceae)
HW
J. B. Harborne Jan-SBBU
Type Structure (name) Genus, species
(family)
Location
(b=Bark, W=Wood, HW-Heart wood)
5,7,2' ,4' -tetrahydroxy derivatives
• artocarpesin
• cycloartocarpesin
• oxydihydroartocarpesin
Artocarpus spp.
(Moraceae)
HW
• oxydihydroartocarpesin
• norartocarpin
• cycloartocarpin
• chaplashin
• integrin
• mulberrin
‫پهل‬ ‫روٹ‬
5,7,2',4' ,5' -pentahydroxy derivatives
• cycloheterophyllin
• isocycloheterophyllin
• heterophyllin
Artocarpus spp.
(Moraceaea)
B
J. B. Harborne Jan-SBBU
Type Structure (name) Genus, species
(family)
Location
(family) (b=Bark, W=Wood, HW-Heart wood)
Flavone O-glycosides
chrysin 5-glucoside
chrysin 7 -glucoside
Rosaceae B
W
Flavone C-glycosides
apigenin 8-glucoside (vitexin)
apigenin 6-glucoside (isovitexin)
agipenin 6,8-diglycosides
V. ucens
(Verbenaceae)
HW
J. B. Harborne Jan-SBBU
Bioflavonoids and their sources (from "Anti-inflammatory activity of natural dietary flavonoids" Min-Hsiung Pan, Food Funct., 2010, 1, 15-31Jan-SBBU
Bioflavonoids and their sources (from "Anti-inflammatory activity of natural dietary flavonoids“
Min-Hsiung Pan, Food Funct., 2010, 1, 15-31. https://pubs.rsc.org/en/content/articlehtml/2010/fo/c0fo00103a
Jan-SBBU
1. Flavones are emerging as very important specialized metabolites involved in
plant signaling and defense, as well as key ingredients of the human diet, with
significant health benefits.
2. Flavones have antioxidant, anti-proliferative, anti-tumor, anti-microbial, acetyl
cholinesterase, anti-inflammatory activities and are also used in cancer,
cardiovascular disease, neurodegenerative disorders, etc*.
*Manjinder Singh, et al. European Journal of Medicinal Chemistry, 84, 2014, 206-239
Jan-SBBU

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1.2 flavons

  • 1. 1. flavones, 2. flavanones, 3. isoflavones, • According to the oxidation status and saturation of the heterocyclic ring, flavonoids are divided into several groups, which include flavones B 4. flavonols, 5. 3-deoxy flavonoids 6. anthocyaninsanthocyanins Flavones comprise one of the largest groups, which are characterized by the presence of a double bond between CC--22 andand CC--33, and the attachment of the B ring to CC--22 A Jan-SBBU
  • 2. Ref. Nan Jiang, Plants 2016, 5(2), 27 Jan-SBBU
  • 3. Occurrence of flavones The various flavones that have been reported in wood or bark of higher plants are listed in Table Type Structure (name) Genus, species (family) Location (b=Bark, W=Wood, HW-Heart wood) Simple flavones • 5,6-dimethoxy Rutaceae B ‫وغيره‬ ‫مالٹا‬• 5,6-dimethoxy Rutaceae B ‫وغيره‬ ‫مالٹا‬ • 5,6,2'-trimethoxy -- B • 5,7,3' ,4' -tetrahydroxy (luteolin) Rosaceae HW C-Methyl flavones • 5,7 -dihydroxy-6-C-methyl • (strobochrysin) Pinus (Pinaceae) HW • 5-hydroxy-7 ,4' -dimethoxy- 6,8-di-Cmethyl (eucalyptin) Eucalyptus (Myrtaceae) HW J. B. Harborne Jan-SBBU
  • 4. Type Structure (name) Genus, species (family) Location (b=Bark, W=Wood, HW-Heart wood) 5,7,2' ,4' -tetrahydroxy derivatives • artocarpesin • cycloartocarpesin • oxydihydroartocarpesin Artocarpus spp. (Moraceae) HW • oxydihydroartocarpesin • norartocarpin • cycloartocarpin • chaplashin • integrin • mulberrin ‫پهل‬ ‫روٹ‬ 5,7,2',4' ,5' -pentahydroxy derivatives • cycloheterophyllin • isocycloheterophyllin • heterophyllin Artocarpus spp. (Moraceaea) B J. B. Harborne Jan-SBBU
  • 5. Type Structure (name) Genus, species (family) Location (family) (b=Bark, W=Wood, HW-Heart wood) Flavone O-glycosides chrysin 5-glucoside chrysin 7 -glucoside Rosaceae B W Flavone C-glycosides apigenin 8-glucoside (vitexin) apigenin 6-glucoside (isovitexin) agipenin 6,8-diglycosides V. ucens (Verbenaceae) HW J. B. Harborne Jan-SBBU
  • 6. Bioflavonoids and their sources (from "Anti-inflammatory activity of natural dietary flavonoids" Min-Hsiung Pan, Food Funct., 2010, 1, 15-31Jan-SBBU
  • 7. Bioflavonoids and their sources (from "Anti-inflammatory activity of natural dietary flavonoids“ Min-Hsiung Pan, Food Funct., 2010, 1, 15-31. https://pubs.rsc.org/en/content/articlehtml/2010/fo/c0fo00103a Jan-SBBU
  • 8. 1. Flavones are emerging as very important specialized metabolites involved in plant signaling and defense, as well as key ingredients of the human diet, with significant health benefits. 2. Flavones have antioxidant, anti-proliferative, anti-tumor, anti-microbial, acetyl cholinesterase, anti-inflammatory activities and are also used in cancer, cardiovascular disease, neurodegenerative disorders, etc*. *Manjinder Singh, et al. European Journal of Medicinal Chemistry, 84, 2014, 206-239 Jan-SBBU