1. Which class of chemical messenger facilitates WBC formation in bo.docx
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1. Which class of chemical messenger facilitates WBC formation in bone marrow? A Interleukins b. tumor necrotic factors c. colony stimulating factors d. Interferons 2. Often a virus infected cell will release ___________to prevent spread of the infection. a. histamine b. Interferon c. compliment d. perforni 3. In the classical pathway of complement activation: a. compliment is activated within liver cells & released into the blood b. complement binds to an antibody that is bound to a foreign substance c. complement bonds with polysaccharides on a microbial cell wall d. complement inhibits inflammation & binds to apianins 4. A membrane attack complex is a protein that: a. triggers phagocytes of a target cell by a nearby macrophage or Europhile b. Forms a channel in the target cell membrane that causes cytolysis c. links a pathogen to a RBC so that it is carried to the liver or spleen d. stimulates basophils to attack a multicultural parasite in the body 5. Exudate refers to: a. blood that escapes capillaries passes beyond the skin and leaves the body. b. increased perfussion of capillary beds within the region of an injury c. lymph that flows away from the heart and toward the site of injury. d. fluid that leaves capillaries to “wash” the interstitial space of an injured tissue e. clotting proteins that wall off microbes and prevent them from spreading through the bloodstream. 6.Which is not one of the cardinal signs of inflammation? a. heat b.redness c. loss of function d. numbness e. swelling 7. Sustained fevers that are 1’C above normal core body temperature usually lead to irreversible brain damage: a. True b. False c. Not sure 8. Antigens are: a. something made by a WBC to destroy a pathogen b. something that an antibody or T-lymphocyte binds to .
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1.Cash flow information Direct and indirect methodsThe co.docx
1.
Cash flow information: Direct and indirect methods
The comparative year-end balance sheets of Sign Graphics, Inc., revealed the following activity in the company's current accounts:
20X5
20X4
Increase / Decrease)
Current assets
Cash
$55,400
$35,200
$20,200
Accounts receivable (net)
83,800
88,000
-4,200
Inventory
243,400
233,800
9,600
Prepaid expenses
25,400
24,200
1,200
Current liabilities
Accounts payable
$123,600
$140,600
($17,000)
Taxes payable
43,600
49,200
-5,600
Interest payable
9,000
6,400
2,600
Accrued liabilities
38,800
60,400
-21,600
Note payable
44,000
—
44,000
The accounts payable were for the purchase of merchandise. Prepaid expenses and accrued liabilities relate to the firm's selling and administrative expenses. The company's condensed income statement follows.
SIGN GRAPHICS INC.
Income Statement
for the Year Ended December 31, 20x5
Sales
$713,800
Less: Cost of goods sold
323,000
Gross profit
$390,800
Less: Selling & administrative expenses
$186,000
Depreciation expense
17,000
Interest expense
27,000
230,000
Add: gain on sale of land
$160,800
21,800
Income before taxes
$182,600
Income taxes
36,800
Net income
$145,800
Other data:
1.
Long-term investments were purchased for cash at a cost of $74,600.
2.
Cash proceeds from the sale of land totaled $76,200.
3.
Store equipment of $44,000 was purchased by signing a short-term note payable. Also, a $150,000 telecommunications system was acquired by issuing 3,000 shares of preferred stock.
4.
A long-term note of $49,400 was repaid.
5.
Twenty thousand shares of common stock were issued at $5.19 per share.
6.
The company paid cash dividends amounting to $128,600.
Instructions:
a.
Prepare the operating activities section of the company's statement of cash flows, assuming use of:
1.
The direct method.
2.
The indirect method.
b.
Prepare the investing and financing activities sections of the statement of cash flows.
.
1.Cash flow information Direct and indirect methodsThe comp.docx
1.
Cash flow information: Direct and indirect methods
The comparative year-end balance sheets of Sign Graphics, Inc., revealed the following activity in the company's current accounts:
20X5
20X4
Increase / Decrease)
Current assets
Cash
$55,400
$35,200
$20,200
Accounts receivable (net)
83,800
88,000
-4,200
Inventory
243,400
233,800
9,600
Prepaid expenses
25,400
24,200
1,200
Current liabilities
Accounts payable
$123,600
$140,600
($17,000)
Taxes payable
43,600
49,200
-5,600
Interest payable
9,000
6,400
2,600
Accrued liabilities
38,800
60,400
-21,600
Note payable
44,000
—
44,000
The accounts payable were for the purchase of merchandise. Prepaid expenses and accrued liabilities relate to the firm's selling and administrative expenses. The company's condensed income statement follows.
SIGN GRAPHICS INC.
Income Statement
for the Year Ended December 31, 20x5
Sales
$713,800
Less: Cost of goods sold
323,000
Gross profit
$390,800
Less: Selling & administrative expenses
$186,000
Depreciation expense
17,000
Interest expense
27,000
230,000
Add: gain on sale of land
$160,800
21,800
Income before taxes
$182,600
Income taxes
36,800
Net income
$145,800
Other data:
1.
Long-term investments were purchased for cash at a cost of $74,600.
2.
Cash proceeds from the sale of land totaled $76,200.
3.
Store equipment of $44,000 was purchased by signing a short-term note payable. Also, a $150,000 telecommunications system was acquired by issuing 3,000 shares of preferred stock.
4.
A long-term note of $49,400 was repaid.
5.
Twenty thousand shares of common stock were issued at $5.19 per share.
6.
The company paid cash dividends amounting to $128,600.
Instructions:
a.
Prepare the operating activities section of the company's statement of cash flows, assuming use of:
1.
The direct method.
2.
The indirect method.
b.
Prepare the investing and financing activities sections of the statement of cash flows.
.
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1. The lymphatic system differs from the cardiovascular system in that
a. the lymphatic system only carries fluid away from tissues.
b. the lymphatic vessels have their own "pump" to assist flow.
c. lymph capillaries do not contain any fluid.
d. lymph capillaries allow free movement of fluid in and out of the capillaries.
e. lymph circulates fluids and cardiovascular does not.
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a. interfere with breathing when enlarged.
b. are located at the junction of the oral cavity and pharynx.
c. are located superior to the palate.
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e. are located in the nasopharynx.
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b. phagocytosis of invading organisms
c. washing action of tears and saliva
d. inflammation
e. release of histamine
4. Which of the following is usually the first cell type to leave the blood and enter infected tissues?
a. eosinophil
b. lymphocyte
c. monocyte
d. natural killer cell
e. neutrophil
5. Transplanted tissues and organs that contain _________ _________ are rejected by the body.
a. self antigens
b. foreign antigens
c. foreign antibodies
d. auto antigens
e. plasma proteins
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a. B cell clones.
b. extracellular antigens.
c. the displaying cell.
d. mature red blood cells.
e. the virus inside the cell, but not the cell.
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a. Most nucleated cells process antigens through the MHC class I mechanisms.
b. Viral antigens are processed by the MHC class I mechanism and are presented to the cell surface.
c. Cytotoxic T cells bind to MHC class I processed antigens.
d. Cytotoxic T cells bound to the MHC class I processed antigens release lymphokines.
e. All of these choices are correct.
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a. produce antibodies for general circulation.
b. attach to the surface of cells causing them to lyse.
c. cause precipitation of antigens.
d. have IgG antibodies on their cell membranes.
e. are destroyed after contact killing.
9. Which of the following is false?
a. The HIV virus binds to the CD4 molecule of host cells.
b. There is currently only one cure for AIDS - AZT.
c. Most manifestations of AIDS are explained by the loss of helper T cell functions.
d. Once infected by the virus, a person will test positive for HIV antibodies.
e. In order for HIV to replicate, viral RNA is used to make viral DNA, which is inserted into the host cell's DNA.
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b. an innate immune response.
c. hypersensitivity.
d. excess immunit.
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Microbial pathogens can cause disease through several mechanisms:
1. They produce toxins or enzymes like exotoxins and endotoxins that damage host cells. Common exotoxins include neurotoxins and enterotoxins.
2. They secrete adhesins and other factors like capsules that help them attach to and evade host defenses, making it easier to infect tissues.
3. After entering through mucous membranes or breaks in the skin, pathogens must overcome the host's immune responses and outgrow the local microbiota to cause illness. Virulence factors play an important role in this process.
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Microbial pathogens can cause disease through several mechanisms:
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2. They secrete adhesins and other factors like capsules that help them attach to and penetrate host defenses, making it easier for the pathogens to infect cells.
3. After entering through openings in mucus membranes or breaks in the skin, pathogens must overcome the host's immune responses and outcompete normal microbiota to cause illness. The ability of a microbe to do this is known as its pathogenicity and virulence.
2_2019_10_26!04_54_11_PM.ppt
The document discusses infectious diseases and infectious agents. It covers host barriers to infection like the skin, respiratory system, gastrointestinal tract, and urogenital tract. It describes how these barriers can fail and allow infection. It also discusses the different classes of infectious agents including bacteria, viruses, fungi and parasites. The document outlines the different types of inflammatory responses infections can cause like suppurative inflammation, granulomatous inflammation, and cytopathic responses. It covers how microbes can evade the immune system and the various ways infections can be transmitted.
The substances which are recognized by the immune system as being fo.pdf
The substances which are recognized by the immune system as being foreign and that the
immune system reacts against are termed:
Along the alimentary and respiratory tracts, mucus is produced:
A. to lyse the microbes
B. to coat the microbes and prevent them from undergoing genetic changes
C. to aggregate the microbes and make them easier for the body to get rid of them
D. to coat the microbes and act as attractants for phagocytic cells
What triggers activation of complement by the classical pathway?
C. interleukines bind to microbial surface which then attracts complement
D. interferon binds to microbial surface which then attracts complement
The following events occur during the inflammatory process. Which would be the step that is
interfered with directly if the bacterium possesses a capsule?.
Chapter 2 Immunology
The document summarizes key aspects of innate immunity in 3 paragraphs or less:
Innate immunity provides the first line of defense against pathogens and includes physical barriers and fixed mechanisms that are always ready. It responds immediately through mechanisms like antimicrobial peptides, complement proteins that tag pathogens, and pattern recognition receptors on macrophages that help clear infections. Phagocytes like macrophages and neutrophils work to eliminate invading pathogens through receptors, phagocytosis, and secretion of inflammatory cytokines and chemokines to recruit more immune cells. Together the fixed and cellular defenses of innate immunity function to quickly control infections before the adaptive immune response is deployed.
Types of toxins
Bacterial toxins can be divided into exotoxins and endotoxins. Exotoxins are toxic proteins released from bacterial cells and include cytolytic toxins, AB toxins, and superantigens. Cytolytic toxins damage cell membranes, AB toxins consist of subunits that damage cells, and superantigens trigger cytokine storms. Endotoxins are lipopolysaccharides in Gram-negative bacterial membranes that are released upon cell lysis and cause fever, shock, and organ failure by activating the host immune response. Bacterial toxins contribute to pathogenesis by directly damaging host cells or disabling the immune system.
Ap+Bio+Hbs+Master
The document summarizes key concepts about the immune system, including innate immunity, acquired immunity, lymphocytes, antibodies, phagocytosis, and the roles of B cells, T cells, and macrophages. Innate immunity provides nonspecific defenses like skin, mucus, and antimicrobial proteins. Acquired immunity develops from exposure to antigens and produces targeted responses like antibodies. Lymphocytes include B and T cells that carry out humoral and cellular immunity.
A P+ Bio+ H B S+Master
The document summarizes key concepts about the immune system, including innate immunity, acquired immunity, lymphocytes, antibodies, phagocytosis, and the roles of B cells, T cells, and macrophages. Innate immunity provides nonspecific defenses like skin, mucus, and antimicrobial proteins. Acquired immunity develops from exposure to antigens and produces targeted responses like antibodies. Lymphocytes include B and T cells that carry out humoral and cellular immunity.
molecular mechanism of pathogenesis
1) Pathogenesis is the development of a disease caused by an infectious agent like a microbe. It involves the microbe overpowering the host's defenses through steps like transmission, colonization, adhesion, invasion, survival, and tissue injury.
2) Microbes have various mechanisms that allow them to cause disease, including producing toxins or enzymes that damage tissues or avoid host defenses. They may also form protective capsules or adhere tightly to host cells.
3) The degree of pathogenicity or ability to cause disease depends on factors like infectious dose, routes of transmission, and virulence factors that help microbes overcome host defenses.
Immunology and Serology.ppt
Immunology and Serology.pptHajee Mohammad Danesh Science and Technology University, Dinajpur-5200,Bangladesh
Immunology and serology is an important issue for medical science both veterinary and human medical science .The presentation shows general study about immunology and serology Immunity-simplified
This document provides an overview of immunology concepts and terminology. It begins with definitions of key terms like antigen, antibody, innate immunity and acquired immunity. It then describes in more detail:
- The cells and organs involved in the immune system like B cells, T cells, lymph nodes, spleen.
- Types of immunity like natural, artificial, active, passive.
- Mechanisms of innate immunity like epithelial barriers, mucus, cilia, antimicrobial peptides, inflammation, fever.
- Antigen-antibody reactions like precipitation, agglutination, complement fixation, neutralization.
- Structure and properties of antibodies like IgG, IgM, IgA classes.
So
Microbial_Pathogenicity.pdf
Pathogenic microbes cause disease through their ability to invade tissues (invasiveness) and produce toxins (toxigenesis). The degree of pathogenicity depends on factors related to the host, microbe, and environment. For a microbe to cause disease, it must gain access to and adhere to the host, penetrate host defenses, and damage tissues directly or through microbial waste products. Bacterial pathogens contribute to diseases like pneumonia and foodborne illness through various virulence factors that help them colonize, avoid host defenses, and damage host cells and tissues.
INFLAMMATION
This document discusses the definition, types, and processes of inflammation. It defines inflammation as the body's response to injury and lists the four classic signs. It describes the differences between acute and chronic inflammation and the roles of chemical mediators like histamine, cytokines, and prostanoids in each type. Key cellular events in acute inflammation include increased blood flow, vascular permeability, and leukocyte migration into tissues. The document also provides brief histories of discoveries related to inflammation.
Immune system
The document summarizes key aspects of the immune system, including:
1. It describes some of the nonspecific defenses of the skin and mucous membranes, as well as the inflammatory response involving histamine, phagocytes, neutrophils, and natural killer cells.
2. The specific defenses are outlined, including lymphatic organs like the bone marrow, thymus, lymph nodes, spleen, tonsils, and adenoids.
3. The roles of lymphocytes, antigens, antibodies, and cytokines in the immune response are summarized, along with how vaccination works to introduce antigens and provide immunity.
Mechanism of bacterial pathogenesis
This document discusses the mechanisms of bacterial pathogenesis. It defines key terms like commensal, opportunistic pathogen, pathogen, virulence, infection, and portal of entry. It describes bacterial virulence factors such as capsules, adhesins, invasiveness, exoenzymes, and toxins. It also discusses concepts like infecting dose, clinical manifestations, and the evolution of infection.
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1.Cash flow information Direct and indirect methodsThe co.docx
1.
Cash flow information: Direct and indirect methods
The comparative year-end balance sheets of Sign Graphics, Inc., revealed the following activity in the company's current accounts:
20X5
20X4
Increase / Decrease)
Current assets
Cash
$55,400
$35,200
$20,200
Accounts receivable (net)
83,800
88,000
-4,200
Inventory
243,400
233,800
9,600
Prepaid expenses
25,400
24,200
1,200
Current liabilities
Accounts payable
$123,600
$140,600
($17,000)
Taxes payable
43,600
49,200
-5,600
Interest payable
9,000
6,400
2,600
Accrued liabilities
38,800
60,400
-21,600
Note payable
44,000
—
44,000
The accounts payable were for the purchase of merchandise. Prepaid expenses and accrued liabilities relate to the firm's selling and administrative expenses. The company's condensed income statement follows.
SIGN GRAPHICS INC.
Income Statement
for the Year Ended December 31, 20x5
Sales
$713,800
Less: Cost of goods sold
323,000
Gross profit
$390,800
Less: Selling & administrative expenses
$186,000
Depreciation expense
17,000
Interest expense
27,000
230,000
Add: gain on sale of land
$160,800
21,800
Income before taxes
$182,600
Income taxes
36,800
Net income
$145,800
Other data:
1.
Long-term investments were purchased for cash at a cost of $74,600.
2.
Cash proceeds from the sale of land totaled $76,200.
3.
Store equipment of $44,000 was purchased by signing a short-term note payable. Also, a $150,000 telecommunications system was acquired by issuing 3,000 shares of preferred stock.
4.
A long-term note of $49,400 was repaid.
5.
Twenty thousand shares of common stock were issued at $5.19 per share.
6.
The company paid cash dividends amounting to $128,600.
Instructions:
a.
Prepare the operating activities section of the company's statement of cash flows, assuming use of:
1.
The direct method.
2.
The indirect method.
b.
Prepare the investing and financing activities sections of the statement of cash flows.
.
1.Cash flow information Direct and indirect methodsThe comp.docx
1.
Cash flow information: Direct and indirect methods
The comparative year-end balance sheets of Sign Graphics, Inc., revealed the following activity in the company's current accounts:
20X5
20X4
Increase / Decrease)
Current assets
Cash
$55,400
$35,200
$20,200
Accounts receivable (net)
83,800
88,000
-4,200
Inventory
243,400
233,800
9,600
Prepaid expenses
25,400
24,200
1,200
Current liabilities
Accounts payable
$123,600
$140,600
($17,000)
Taxes payable
43,600
49,200
-5,600
Interest payable
9,000
6,400
2,600
Accrued liabilities
38,800
60,400
-21,600
Note payable
44,000
—
44,000
The accounts payable were for the purchase of merchandise. Prepaid expenses and accrued liabilities relate to the firm's selling and administrative expenses. The company's condensed income statement follows.
SIGN GRAPHICS INC.
Income Statement
for the Year Ended December 31, 20x5
Sales
$713,800
Less: Cost of goods sold
323,000
Gross profit
$390,800
Less: Selling & administrative expenses
$186,000
Depreciation expense
17,000
Interest expense
27,000
230,000
Add: gain on sale of land
$160,800
21,800
Income before taxes
$182,600
Income taxes
36,800
Net income
$145,800
Other data:
1.
Long-term investments were purchased for cash at a cost of $74,600.
2.
Cash proceeds from the sale of land totaled $76,200.
3.
Store equipment of $44,000 was purchased by signing a short-term note payable. Also, a $150,000 telecommunications system was acquired by issuing 3,000 shares of preferred stock.
4.
A long-term note of $49,400 was repaid.
5.
Twenty thousand shares of common stock were issued at $5.19 per share.
6.
The company paid cash dividends amounting to $128,600.
Instructions:
a.
Prepare the operating activities section of the company's statement of cash flows, assuming use of:
1.
The direct method.
2.
The indirect method.
b.
Prepare the investing and financing activities sections of the statement of cash flows.
.
1.At least 500 words APA Style2.Clear, logical f.docx
1.
At least
500
words
APA Style
2.
Clear, logical
flow post
3.
Major points are stated
clearly
4.
Cited at least 3,
you
must cited all the source
5.
Good example conceptual or personal
examples are acceptable
6.
Thoughtful analysis
(Considering assumptions, analyzing implications,
comparing/ contrasting concepts)
7.
It must be proofread for Spelling and grammar
I will not release any payment until everything is met.
Evaluate the ethicality of the gift and estate tax
when earnings have been taxed throughout one’s life.
Justify your answer.
The project is due 10 hrs from now sir!
.
1.Assess the level of interdependence between planning, program eval.docx
1.Assess the level of interdependence between planning, program evaluation, human resource management, and budgeting. Create a scenario in which you explain the overall manner in which these functions interact.
2.Construct two (2) competencies that public personnel managers need to possess in order to minimize the impact of political preference in program implementation. Justify your response.
3.Take a position on whether the politics of budgeting have negatively or positively impacted outcomes on budget policy and formation overall. Provide a rationale for your response.
4.Analyze the main variables that impact the relationship between political responsiveness and managerial effectiveness. Propose two (2) challenges that political responsiveness may present for management (Note: You will explore your proposed challenges in depth within Assignment 3).
5.Include at least four (4) academic references (no more than five [5] years old) from material outside the textbook and no more than one (1) governmental Website. Note: Appropriate academic resources include academic and governmental Websites, scholarly texts, and peer-reviewed articles. Wikipedia, other wikis, and any other Websites ending in anything other than “.gov” do not qualify as academic resources.
.
1.Assign values to variable num1 to 100 and num2 to 20a.Fi.docx
This document provides instructions for a class assignment to assign values to variables num1 and num2, rename the worksheet with the student's name and class assignment number, and submit it. It includes code snippets to import namespaces for use in a C# program or code file.
1.Antique Reproductions, Inc. estimates its manufacturing costs .docx
1.
Antique Reproductions, Inc. estimates its manufacturing costs as follows:
Variable Costs
Direct material
$5.50/unit
Direct labor
2.40/unit
Variable overhead
1.00/unit
Fixed Costs
Supervisor’s salary
$15,000
Production facility depreciation
7,500
Other production costs
1,400
Estimate manufacturing costs for manufacturing levels of 9,000 units, 11,000 units, and 13,000 units.
2.
Southern Pecan Company grows and sells pecans. The company harvested 10,000 bags of pecans in May and sold everything that it harvested. The company’s flexible budget for May was:
Bags sold
10,000
Revenue ($10/bag)
$100,000
Expenses:
Bags ($.50 each)
$ 5,000
Pecan orchard maintenance
$ 10,000
Wages and salaries ($2,400 + $.50 per bag)
$ 7,400
Shipping ($.40 per bag)
$ 4,000
Other expenses ($1,000 + $.45 per bag)
$ 5,500
Total Expenses
$ 31,900
Net operating income
$ 68,100
The actual results for May were:
Bags sold
10,000
Revenue ($10/bag)
$105,000
Expenses:
Bags ($.50 each)
$ 5,100
Pecan orchard maintenance
$ 9,000
Wages and salaries ($2,400 + $.50 per bag)
$ 7,900
Shipping ($.40 per bag)
$ 5,000
Other expenses ($1,000 + $.45 per bag)
$ 5,600
Total Expenses
$ 32,600
Net operating income
$ 72,400
Prepare a report detailing the company’s revenue and spending variances of May.
3.
Tiger Company makes a product and uses the following standard unit costs for that product:
Direct material quantity standard
6 pound per unit
Direct material price standard
$ 9 per pound
Direct labor time standard
3.5 hours per unit
Direct labor rate standard
$12 per hour
Variable manufacturing overhead rate standard
$ 6 per machine hour
Fixed manufacturing overhead rate standard
$ 5 per machine hour
Machine hours standard
3 hours per unit
Given the flowing actual cost and usage data, compute the direct labor rate and the direct labor efficiency variances.
4.
With the following information, compute the throughput time and the manufacturing cycle efficiency:
Wait time
12.0 days
Inspection time
0.9 days
Processing time
3.5 days
Move time
0.2 days
Queue time
2.0 days
.
1.Assess the changing complexion of the U.S. labor force and how i.docx
1.
Assess the changing complexion of the U.S. labor force and how it directly affects the role of unionization in the workplace
2.
Given today’s globally competitive work environment, assess whether larger, more powerful unions (such as the AFL-CIO and the SEIU) favorably represent their members, or if smaller, more targeted unions would better meet the needs of their members
.
1.As a critical thinker we have to work with analysis and eval.docx
1.
As a critical thinker we have to work with analysis and evaluation in order to formulate a conclusion.
There are some specific m
istakes in causal reasoning that compromise our ability to make predictions and old reasonable expectations.
Mention and explain them. (Your own words.
2.
Do you think that you can be a trustworthy Critical Thinking Manager?
Yes or No…..WHY?
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1.A new diagnostic test has been developed to Diagnose Disease.docx
1.
A new diagnostic test has been developed to Diagnose Disease Y. The new test was compared to the standard diagnostic test (“the gold standard”) on the same set of patients, and the following data were obtained:
Number of patients diagnosed by the new test as having Disease Y, who actually had Disease Y = 3,252
Number of patients in the group who were diagnosed by the standard test as having Disease Y = 4,579
Number of patients diagnosed by the new test as not having Disease Y = 4, 737
Number of patients diagnosed by the new test as having Disease Y, who actually do not have Disease Y= 784
The standard diagnostic test is a tissue biopsy, and therefore, is considered to be 100% sensitive for diagnosing Disease Y.
a.
Create the 2x2 table that shows this data
b.
Calculate:
i.
The sensitivity of the new test
ii.
The specificity of the new test
iii.
The false positive rate of the new test
iv.
The false negative rate of the new test
v.
The positive predictive value of the new test
vi.
The negative predictive value of the new test
vii.
The likelihood ratio positive for the new test
viii.
The likelihood ratio negative for the new test
2.
Two new tests have been developed to diagnose Condition Z. One test (Test A) measures a metabolite “Metabolite A” in the serum. The other test (Test B) measures a different metabolite, “Metabolite B” in the urine. After appropriate preliminary testing, human trials are conducted. Following informed consent, the two tests were run on a group of patients with each patient getting both tests, as well as the “gold standard” test for diagnosing Condition Z. The following data were obtained:
Important!!!!
Since some answers depend on the results you obtained in previous sections of the problem, it is important for you that you show *all* work, since I will give partial credit if your analysis and set up are correct, even if your numerical result is incorrect.
Serum level (metabolite A)
# of patients
Disease positive
Disease negative
(mg / ml)
(by gold standard)
(by gold standard)
0 – 1.99
25
22
3
2.0 – 3.99
273
201
72
4.0 – 5.99
584
572
12
6.0 – 7.99
538
529
9
8.0 – 9.99
175
170
5
>10.0
14
14
0
Urine level (metabolite B)
(ng/ml)
0 – 2.99
30
5
25
3.0 – 5.99
245
46
199
6.0 – 8.99
423
400
23
9.0 – 11.99
628
620
8
12.0 – 14.99
175
169
6
15.0 – 17.99
99
95
4
>18.0
9
9
0
a)
For test A, a cutoff value of 4.0 mg / ml of metabolite A is chosen as the boundary between a negative and a positive test result (i.e., values below 4.0 mg / ml
are considered “negative” and values of 4.0 mg / ml or greater are considered “positive”).
For test B, a cutoff value of 6.0 ng / ml for metabolite B is chosen as the boundary between a negative and a positive test result (i.e., values below 6.0 ng / ml are considered “negative” and values of 6.0 ng / ml or greater are considered.
1.A repeated melodic and rhythmic figure in the lower register o.docx
1.
A repeated melodic and rhythmic figure in the lower register of the piano is typical of the Afro-Cuban
dance music known as
A.
guaguancó.
B.
reggae.
C.
salsa.
D.
mambo.
2.
Aaron Copeland varies the _______ throughout his movement "Hoe-Down" to create variety.
A.
movements.
B.
theme.
C.
scene.
D.
orchestration.
3.
A musical style that combines traditional and modern elements is called
A.
exhibitionism.
B.
modernism.
C.
minimalism.
D.
postmodernism.
4.
The first African American to have a major opera performed by a major American opera company was
A.
Robert Johnson.
B.
William Grant Still.
C.
Scott Joplin.
D.
Langston Hughes.
5.
In the song "Tonight" from the musical
West Side Story,
the composer distributed two basic melodies
among different characters to create a kind of _______, in which nothing disappears but new layers are
constantly introduced.
A.
dissonant form
B.
layered presence
C.
additive form
D.
consonant counterpoint
6.
A chromatic scale consists entirely of
A.
quarter steps.
B.
whole steps.
C.
half steps.
D.
tonal centers.
7.
The progression of four basic chords that was used in many popular songs of the 1950s and 1960s is
referred to as _______ chord progression.
A.
pop
B.
bebop
C.
vamp
D.
doo-wop
8.
The _______ is a xylophone-like instrument with tubular resonators under each bar.
A.
marimba
B.
suspended cymbal
C.
timbales
D.
conga
9.
John Cage's
Indeterminacy
is an example of _______ music.
A.
aleatory
B.
idiosyncratic
C.
silent
D.
achromatic
10.
Tamra says that the difference between an opera and a musical is that the opera includes more spoken
word than singing. Eduardo says that the musical contains singing with some spoken dialog. Who is correct
in citing the difference?
A.
Both Tamra and Eduardo
B.
Neither Tamra nor Eduardo
C.
Eduardo
D.
Tamra
11.
Einstein on a Beach
was a unique opera because it
A.
had no plot and very little singing.
B.
was written in Chinese.
C.
was exclusively recitative.
D.
had a single violinist.
12.
The type of music that blended the musical styles of jump blues and honky-tonk was
A.
jazz.
B.
Motown.
C.
hip hop.
D.
rock 'n' roll.
13.
Which of the following composers wrote the music for
West Side Story?
A.
George M. Cohan
B.
Jerome Kern
C.
Leonard Bernstein
D.
Cole Porter
14.
The musical movement that started in the mid-1960s on the West Coast was the _______ movement.
A.
rock
B.
folk
C.
psychedelic
D.
progressive
15.
Notes that begin a phrase before a downbeat are known as pick-up notes, or a/an
A.
shuffle groove.
B.
duck walk.
C.
call and response.
D.
anacrusis.
16.
_______ music is based on frequent repetition (with small variations) of a small musical idea.
A.
Atonal
B.
Minimalist
C.
Ostinato
D.
Rap
17.
Which of John Cage's works is perceived by some to be a gimmick?
A.
Einstein on a Beach
B.
4'33"
C.
Illiac Suite
D.
Imaginary Landscape no. 4
18.
The musician who ushered in the twentieth-century era of .
1.A preliminary investigation is conducted by probation officers a.docx
1.
A preliminary investigation is conducted by probation officers at or during:
a. [removed]
intake.
b. [removed]
investigation.
c. [removed]
supervision.
d. [removed]
release of offender.
2.
The United States Supreme Court has ruled that only juveniles over the age of _____ can be executed for their crimes.
a. [removed]
10
b. [removed]
12
c. [removed]
14
d. [removed]
17
3.
What percent of juveniles currently are waived to adult court?
a. [removed]
5 percent
b. [removed]
15 percent
c. [removed]
25 percent
d. [removed]
36 percent
4.
Judges must hold probable cause hearings when:
a. [removed]
prosecutors file to send a juvenile to adult court.
b. [removed]
cases come to the adult court by a mandatory judicial waiver.
c. [removed]
cases come to the adult court by a discretionary judicial waiver.
d. [removed]
all of the choices apply.
5.
The probation official who has replaced the case worker is the:
a. [removed]
police officer.
b. [removed]
community resource manager.
c. [removed]
intake officer.
d. [removed]
referee.
6.
Which is the correct order in which probation services are provided?
a. [removed]
Intake, investigation, supervision
b. [removed]
Supervision, intake, investigation
c. [removed]
Investigation, intake, supervision
d. [removed]
Arrest, intake, investigation, supervision, bail
7.
In order for a state to have a valid death penalty, judges must consider:
a. [removed]
mitigating circumstances.
b. [removed]
statistical ambiguities in demographic trends.
c. [removed]
historical traditions of the court.
d. [removed]
future impact of the penalty on deterring crimes.
8.
According to studies on restitution, which of the following are among the primary goals of restitution programs?
a. [removed]
Hold parents accountable for their children's offenses
b. [removed]
They set-up local programs to fully reimburse victims for their financial damages at their expense
c. [removed]
They hold juveniles accountable for their offenses
d. [removed]
All of the choices apply
9.
The balanced approach in probation focuses on:
a. [removed]
arrest, conviction, and confinement.
b. [removed]
correction, rehabilitation, and aftercare.
c. [removed]
the community, the victim, and the offender.
d. [removed]
both arrest, conviction, and confinement and correction, rehabilitation, and aftercare.
10.
Which of the following are (is/a) goal(s) of electronic monitoring programs?
a. [removed]
To reduce the number of field contacts required by home-confinement officers
b. [removed]
To provide for early unification with the juvenile's family
c. [removed]
To keep the juvenile out of school
d. [removed]
Both to reduce the number of field contacts required by home-confinement officers and to provide for early unification with the juvenile's family
11.
Which of the following is the most widely used organization of probation in the United States?
a. [removed]
Local/judicial
b. [removed]
State/judic.
1.Analyze the value stream by using a flow diagram to map the value .docx
1.Analyze the value stream by using a flow diagram to map the value added and non-valued steps in the process.
2.Analyze sources of waste and variation through the use of a tool recommended in Theme 3.
3.Identify the process drivers and validate them through the use of a tool recommended in Theme 4.
.
1.Aim To develop a supply chain for a food industry.2..docx
1.
Aim: To develop a supply chain for a food industry.
2.
Purpose of supply chain: to reach customers need
3.
Supply chain principles: guide lines--- 7 principles
4.
Strategy --- to supply right product at right time in intersectionist
5.
Implementation procedure:
Discuss relationship with:
Supply chain and logistics
Supply chain strategy
Procurement and inventory management
Business strategy
6.
Discuss how supply chain management and logistics with examples.
Note:
APA style format
6 to 8 pages
.
1.A developmental psychologist (e.g., Jean Piaget) who bases his con.docx
1.A developmental psychologist (e.g., Jean Piaget) who bases his conclusions on intensive study of one child or a few individuals is using the ______ method.
2.In a(n) ______, the scientist deliberately changes one variable and measures the change in some other variable.
3.Though Jesse spent most of his growing years in a succession of foster homes after enduring abuse and neglect, his disposition in cheerful and his relationships are healthy and fulfilling. According to developmentalists, he exhibits ______ (the ability to overcome or bounce from adversity) despite his early experiences.
.
1.A music school in Boyles Height, LA, specializes in teaching the g.docx
1.A music school in Boyles Height, LA, specializes in teaching the guitar and the violin. After a spurt in growth and a few successful years, the school is experiencing a slowdown in sales and stability in its profits due to an increase in competition. The school is in the ________ stage of its life cycle.
•
obsolescence
•
decline
•
growth
maturity
2.
Another basis for decision-making is referred to as ________.
•
ethical practices
•
correct ethics
•
ethical dilemmas
situational ethics
3
What are the four characteristics of a marketing audit?
•
Comprehensive, systematic, independent, and periodic
•
Announced, semi-annually, dependent, and perpetual
•
Dependent, non-comprehensive, quarterly, and unannounced
Simple, unique, randomly, and exclusive
4
With ________ as a target market strategy, the firm concentrates on serving many needs of a particular customer group.
•
market specialization
•
single-segment concentration
•
product specialization
selective specialization
5
A social definition of marketing says ______.
•
marketing is the process of extracting maximum value from consumers to facilitate corporate growth
•
marketing is the process by which individuals and groups obtain what they need and want through creating, offering, and freely exchanging products and services of value with others
•
effective marketing requires companies to remove intermediaries to achieve a closer connection with direct consumers
a company should focus exclusively on achieving high production efficiency, low costs, and mass distribution to facilitate the broadest possible access to the company’s products
6
Which of the following can induce a firm to expand into the international arena?
•
Cater to a domestic mass market
•
A saturated domestic market
•
High income level of domestic consumers
A saturated foreign market
7
Marketers must see themselves as benefit providers. For example, when a shopper purchases new shoes, he or she expects the shoes to cover his or her feet and allow him or her to walk unobstructed. This is an example of what level in the consumer-value hierarchy?
•
Augmented product
•
Pure tangible product
•
Basic product
Potential product
8
Through its cutting-edge point-of-sale inventory, management technology, and highly efficient shipping practices, Wal-Mart is able to keep its inventory expenditure extremely low and to pass these savings on to consumers in the form of low prices. Wal-Mart's strategy is best described as ________.
•
differentiation
•
integrative growth
•
market development
overall cost leadership
9
_______ is an approach that considers different ethnic and cultural segments require targeted marketing campaigns and tactics.
•
Multicultural marketing
•
Specialized marketing
•
Ethnic-based marketing
Diversity marketing
10
BMW's "The ultimate driving machine," American Express' "Don't leave home with.
1.0.550.55 points Previous AnswersWaneAC5 5.4.001..docx
1.
0.55
/0.55 points
|
Previous Answers
WaneAC5 5.4.001.
My Notes |
Question Part
Points
Submissions Used
Sketch the graph of the given function. Check your sketch using technology. HINT [See Example 1.]
f
(
x
) =
x
2
+
2
x
+
1
(a) Indicate the
x
- and
y
-intercepts. (If an answer does not exist, enter DNE.)
x
-intercept
(
x
,
y
) =
y
-intercept
(
x
,
y
) =
(b) Indicate any extrema. (If an answer does not exist, enter DNE.)
(
x
,
y
) =
(c) Indicate any points of inflection. (If an answer does not exist, enter DNE.)
(
x
,
y
) =
(d) Indicate the behavior near points where the function is not defined.
y
→
+
∞
as
x
→
0
y
→
0 as
x
→
−1
y
→
+
∞
as
x
→
−1
y
→
+
∞
as
x
→
1
(e) Indicate the behavior at infinity.
y
→
−
∞
as
x
→
±
∞
y
→
−
∞
as
x
→
−
∞
;
y
→
+
∞
as
x
→
+
∞
y
→
+
∞
as
x
→
−
∞
;
y
→
−
∞
as
x
→
+
∞
y
→
−1 as
x
→
±
∞
y
→
+
∞
as
x
→
±
∞
(a) Indicate the
x
- and
y
-intercepts. (Order your answers from smallest to largest
x
. If an answer does not exist, enter DNE.)
x
-intercept
(
x
,
y
) =
x
-intercept
(
x
,
y
) =
x
-intercept
(
x
,
y
) =
y
-intercept
(
x
,
y
) =
(b) Indicate any extrema. (Order your answers from smallest to largest
x
. If an answer does not exist, enter DNE.)
(
x
,
y
) =
(
x
,
y
) =
(
x
,
y
) =
(
x
,
y
) =
(c) Indicate any points of inflection. (If an answer does not exist, enter DNE.)
(
x
,
y
) =
(d) Indicate the behavior near points where the function is not defined.
y
→
+
∞
as
x
→
0
y
→
0 as
x
→
±
6
y
→
+
∞
as
x
→
±
6
y
→
+
∞
as
x
→
±
3
(e) Indicate the behavior at infinity.
y
→
+
∞
as
x
→
±
∞
y
→
−
∞
as
x
→
−
∞
;
y
→
+
∞
as
x
→
+
∞
y
→
−
∞
as
x
→
±
∞
y
→
+
∞
as
x
→
−
∞
;
y
→
−
∞
as
x
→
+
∞
(a) Indicate the
x
- and
y
-intercepts. (Order your answers from smallest to largest
x
. If an answer does not exist, enter DNE.)
x
-intercept
(
x
,
y
) =
x
-intercept
(
x
,
y
) =
x
-intercept
(
x
,
y
) =
y
-intercept
(
x
,
y
) =
(b) Indicate any extrema. (Order your answers from smallest to largest
x
. If an answer does not exist, enter DNE.)
(
x
,
y
) =
(
x
,
y
) =
(c) Indicate any points of inflection. (If an answer does not exist, enter DNE.)
(
x
,
y
) =
(d) Indicate the behavior near points where the function is not defined.
y
→
+
∞
as
x
→
0
y
→
0 as
x
→
±
3
y
→
+
∞
as
x
→
±
3
y
→
+
∞
as
x
→
±
1
(e) Indicate the behavior at infinity.
y
→
+
∞
as
x
→
±
∞
y
→
−
∞
as
x
→
−
∞
;
y
→
+
∞
as
x
→
+
∞
y
→
−
∞
as
x
→
±
∞
y
→
+
∞
as
x
→
−
∞
;
y
→
−
∞
as
x
→
+
∞
(a) Indicate the
x
- and
y
-intercepts. (If an answer does not exist, enter DNE.)
x
-intercept
(
x
,
y
) =
y
-intercept
(
x
,
y
) =
(b) Indicate any extrema. (Order your answers from smallest to largest
x
. If an an.
1.1. Counting jails and prisons, approximately how many citizens a.docx
1.
1. Counting jails and prisons, approximately how many citizens are incarcerated?
2.
2. Which important scholar argued that criminals and their punishment are functional in society, help to define norms and expectations for conformity?
3.
3. Political liberals and _______________ encouraged reform of the prison system during the Enlightenment Period.
4.
4. Lex talionis embodies which of the following principles?
5.
5. The Penitentiary Act was based upon four core principles where prisoners were confined in solitary cells and labored silently in common rooms. They include
6.
6. How was the existing system of justice altered during the Enlightenment?
7.
7. The __________ was a penitentiary system developed in Pennsylvania in which each inmate was held in isolation from other inmates.
8.
8. During the Progressive Reform Era, two main strategies were implemented. They included improving conditions in social environments and ______________.
9.
9. The Military Commissions Act (MCA) __________ the ability of “unlawful enemy combatants” to file a writ of habeas corpus.
10.
10. Which court decision held the basic elements of procedural due process must be present when decisions are made concerning the disciplining of an inmate?
11.
11. Which case allowed inmates to sue state officials for brutality, inadequate medical care and nutrition, theft of personal property and the denial of basic rights:
12.
12. In Boumediene v. Bush, the Court ruled the detainees at Guantanamo Bay are entitled to:
13.
13. According to the Supreme Court, the term “totality of conditions” may be legally interpreted as:
14.
14. The right to be free from cruel and unusual punishment is found in which Amendment?
15.
15. Experts usually cite _________ as reasons wrongful convictions occur.
16.
16. Probationary sentences emphasize guidance and ______________ in the community.
17.
17. In the Booker decision, the justices said that sentencing guidelines are:
18.
18. Restorative justice sees crime as a violation against which of the following?
19.
19. Which of the following is an argument for a centralized probation authority?
20.
20. Which of the following was not an innovation initially developed by John Augustus?
21.
21. Between 1200 and 1827, English law:
22.
22. Recognizance was first used in court to recognize a formally recorded ___________to perform some act entered by a judge to permit an offender to live in the community.
23.
23. Judges may use a range of ________________ sanctions from those exerting a low level of control to those exerting a high level of control.
24.
24. The concept of community corrections is best understood as a goal. That goal clearly is to:
25.
25. The new movement that seeks to establish correctional programs falling between standard probation and prison is called:
26.
26. A major criticism of probation, as traditionally practiced, is that:
27.
27. Probation granted under conditions of strict reporting to a probation offic.
1.20(1 pts.) In the 70s, Dr. Richard Raskin underwent a radical su.docx
Dr. Richard Raskin underwent surgery in the 1970s to change his assigned sex from male to female. Prior to the surgery, Dr. Raskin likely would have been diagnosed with gender identity disorder based on wanting to live as a woman. John gets nauseous thinking about sex and avoids sexual advances, so he may be diagnosed with sexual aversion disorder. Joseph experiences intense genital pain during sex, so he may have dyspareunia.
1.A department store chain is designing a layout for a new.docx
1.
A department store chain is designing a layout for a new store. The store manager wants to provide as much convenience as possible for her customers. Based on historical data, the number of trips between departments per hour is given in the following closeness matrix. A block plan showing a preliminary layout is also shown.
Closeness Factors (Trips per hour)
1/O
2/S
3/H
4/T
5/A
6/E
1. Office Supplies (O)
---
40
100
50
20
10
2. Sporting Goods (S)
---
100
80
60
80
3. Hardware (H)
---
70
100
50
4. Toys (T)
---
70
90
5. Automotive (A)
---
60
6. Electronics (E)
---
OFFICE SUPPLIES
SPORTING GOODS
3. HARDWARE
4. TOYS
5. AUTOMOTIVE
1.
ELECTRONICS
Customer travel between departments is restricted to the aisles shown in the block plan as dotted lines.
CALCULATIONS TABLE
:
Dept. Pair
Closeness Factor (
w
)
Original Distance (
d
O
)
w
´
d
O
Revision #1 Distance (d
1
)
w
´
d
1
1 – 2
1 – 3
1 – 4
1 – 5
1 – 6
2 – 3
2 – 4
2 – 5
2 – 6
3 – 4
3 – 5
3 – 6
4 – 5
4 – 6
5 – 6
TOTAL
Complete the calculations and fill in the table above.
Based on the table above answer the following questions.
a)
What is the total expected weighted-distance score between Office Supplies and Hardware?
b)
What is the total weighted-distance score between Hardware and Toys?
c)
What is the total weighted-distance score for the entire store?
d)
A suggestion has been made to switch Hardware and Automotive. What would the total weighted-distance score for the entire store if these two departments were switched?
e)
Based on your calculations, would you recommend that Hardware and Automotive be switched?
.
1.1 How does speaker intent differentiate informative, persu.docx
1.
1
How does speaker intent differentiate informative, persuasive, and special-occasion speaking?
2.
2
How do the three types of informative speeches differ?
3.
3
What are the characteristics of an effective informative speech?
4.
4
How can effective visuals enhance an informative speech?
5.
5
What role does ethics play in informative speaking?
.
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