The pituitary gland is a small oval shaped gland located at the base of the cranium that weighs between 0.5-0.6g. It acts as the "master gland" that secretes hormones which directly or indirectly affect other glands and organ systems. The pituitary has two parts - the neurohypophysis which secretes oxytocin and vasopressin, and the adenohypophysis which secretes hormones like growth hormone, TSH, ACTH, and others that impact the thyroid, adrenals, testes and ovaries. Acromegaly is a chronic disease caused by excess growth hormone after epiphyseal plate closure, leading to overgrowth of soft tissues and bones.