ppt done by me during internship ... had tp present it to my fellow cointerns... it ws done only to create awareness about the drugs wich were presently avalable at our pharmacy in rhtc Mandur

1. ISOSORBIDE DINITRATE
ISOSORBIDE MONONITRATE
ANTI ANGINAL DRUGS

2. ANGINA PECTORIS

3. CLASSICAL ANGINA

4. Attacks during rest or sleep due
to
vaso spasm
PRINZMETALS ANGINA

5. frequency
Duration
Intensity
At rest
UNSTABLE ANGINA

6. Long Acting Nitrates
Isosorbide dinitrate
Isosorbide mononitrate
Nitrates Available at our pharmacy

7. Actions:
REDUCTION IN PRELOAD
REDUCTION IN AFTERLOAD
REDISTRIBUTION OF BLOOD
FLOW

9. Isosorbide dinitrate
ROUTE OF ADMINISTRATION :
SUBLINGUAL AT TIME OF ATTACK
ORAL FOR CHRONIC PROPHYLAXIS
DOSAGE FORMS – SUBLINGUAL AND ORAL
TABS
-SUSTAINED RELEASE
DURATION OF ACTION : 20-40 MIN
SR– 6-10hrs
DOSAGE : 5-10mg SL, 10-20 mg oral
for prophylaxis 20-40 mg

10. Isosorbide mononitrate
ACTIVE METABOLITE OF IDN
ROUTE OF ADMINISTRATION : ORAL
DOSAGE FORMS – ORAL TABS
- SUSTAINED RELEASE
LONGER ACTING (4-6 HRS).. ONCE A DAY
DOSAGE
DOSAGE 20-40 MG ORAL

11. Indications:
•ANGINA PECTORIS
• ACUTE CORONARY
SYNDROME
•MYOCARDIAL INFARCTION
•CHF AND ACUTE LVF
•OESOPHAGEAL SPASM
• BILIARY COLIC

12. SIDE EFECTS:
THROBBING HEADACHES
 PALPITATIONS
SWEATING
DIZZINESS &FAINTING
FLUSHING
WEAKNESS
TOLERANCE
DEPENDENCE