Software lenses combine visual analysis algorithms, semi-automatic image contexts, and innovative image metrics to analyze single images and process high throughput data. Image metrics are interpreted by expert users to study short series, find averages, and determine reference values. These reference values are then used by less skilled users to select particular images within specific ranges for varying visualization parameters and metric variables. The software reveals new depth, perspectives, and hitherto invisible structures for visual analysis. It also offers metric investigation for any context at any scale and imaging technology through quantifications and real-time processing of large amounts of images.

1. “ Software Lenses” A New Instrument of Investigation to Analyze Single Images and Process High Throughput

2. The human mind is a poor instrument for processing large series of images. “ Software Lenses” combine visual analysis algorithms with semi-automatic image contexts and innovative “ image metrics ”. The Problem and the Solution

3. Image metrics are interpreted by expert users to study short series find averages and determine reference values. Embedding Human Expertise Output Input

4. Reference values are used by less skilled users to select particular images between specific ranges for varying visualization parameters and metric variables. Supporting Decisions Association Output Type of Images Patterns Shape Size Lower Limit Upper Limit Project Series Metrics 1 Metrics 2 Select Criterion 1 Select Criterion 2 Cytology Average Dye Colour Average Cell Size Dye Colour Cell Size Volvox cells 0.111 11 0.1234 0.15 Stem cells 0.222 22 0.2345 0.26 Sickle cells 0.333 33 0.3456 0.37 Blood cells 0.444 44 0.4567 0.48 Red blood cells 0.555 55 0.5678 0.59

5. Output For visual analysis , the software reveals: new depth new perspectives hitherto invisible structures. Due to its generic nature, the software offers metric investigation : for any context at any scale and any imaging technology quantifications for any aspect real time functionality for processing large amounts. Input Images Re-Visualized

6. Re-Visualizations as Proof of “3d metric” Concepts Prototype software re-visualizes individual images. It proves that the “3d metric” approach is worth developing for high throughput processing. As a first application, the cytology / pathology market is a multi-billion market and growing .