this is presentation in biomedical engineering field. it shows a new invention for diabetic. it is a glucose nansensor that helps to minimize the need for the implantation of electrochemical sensors , which minimizes patient inconvenience and pain.

1. PRESENT BY
ROZANA ABOALKHAIR
GLUCOSE NANOSENSOR
TATTOO

2. OVERVIEW
• INTRODUCTION
• GLUCOSE NANOSENSOR TOOLS
i- INJECTOR
ii-NANOSENSOR TATTO
iii- IMAGING DEVICE
• CONCLUSION

3. Diabetes Has Become Epidemic
• Every day,
 3,600 new cases of diabetes are diagnosed.
 580 people die of diabetes-related complications.
 225 people have a diabetes-related amputation.
 120 people with diabetes progress to end-stage renal disease.
 55 people with diabetes become blind.
American diabetes association, May,2012.

4. GLUCOSE NANOSENSOR TOOLS
• Injector
• Nanosensor tattoo
• Imaging device
Trends in Molecular Medicine, Volume 16, Issue 12,
584-593, 23 September 2010

5. PLACEMENT IN SKIN
Skin Pharmacol Physiol,2009

6. PLACEMENT IN SKIN
Skin Pharmacol Physiol,2009

7.  Nanosensors composed of a
hydrophobic polymer containing:
• Lipophilic glucose recognition
elements
(boronic acid derivatives, PhB(OH)2 )
• Fluorescent reporters.
(alizarin, C14H8O4 )
Trends in Molecular Medicine, Volume 16, Issue 12, 584-593, 23 September
2010
NANOSENSOR TATTOO COMPONENTS

8. Imaging Device
Trends in Molecular Medicine, Volume 16, Issue 12, 584-593, 23 September
2010

9. CONCLUSION
• minimize the need for the implantation of electrochemical sensors , which minimizes
patient inconvenience and pain.
• Can performed when the patient is sleeping.
• Provide a means to measure the glucose levels continuously instead of only specific time.
• It would be an additional cost of producing this smart tattoo, by thoroughly comparing the
smart tattoo with other commercially available nanosensors.
• The tattoo, like most cutting-edge technologies have drawbacks, but can be turned
around to full efficiency.

10. Reference
• American Diabetes Association. (2012). "Diabetes Basics.”
• Cash, Kevin J., and Heather A. Clark. "Nanosensors and nanomaterials for monitoring
glucose in diabetes." Trends in molecular medicine 16.12 (2010): 584-593.
• Card, Jeffrey W., and Bernadene A. Magnuson. "A review of the efficacy and safety of
nanoparticle-based oral insulin delivery systems." American Journal of Physiology-
Gastrointestinal and Liver Physiology 301.6 (2011): G956-G967.

11. THANK YOU…