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Immunity
• Immunity referred to the resistance exhibited by
the host towards injury cauesd by microorganism
and their products.
• Protection against dieases is only one of the
many consequence of immune response.
• There are two types of immunity :
1:Innate immunity
2:Acquired immunity,
Funtionally, an immune response can be divides
into two related activites –recognition and
response.
Innate immunity
• It is inborn capacity of the body to resist pathog-
ens.
It eliminates them before development of any
disease
It is also called non specific or natural immunity,
although its efficacy improves when pathogens
enters in the body.
The cell that mediate immunity are neutrophils,
macrophage, natural killer and large lymphocyte.
Acquired immunity
• It acquires during life and clear from innate
immunity.
• It is of two types-Active and Passive immunity
• Active –It is resistance developed by an
individual as a result of an antigenic stimulus.
It is either natural or artificial.
• Passive - the resistance that is transmitted to a
recipient in a readymade form
Humoral (acquired)
• It is expressed through circulating proteins
called antibody
• Antibodies are gammaglobulins and are
developed by B lymlphocytes.
• The mloecule that induced antibody called
anitgens .
Cell mediated (acquired)
• It is generally invoked for dealing with
organism which prefers to stay with in the
host cells.
• It is expressed by large lymphocytes known as
T lymphocytes.
• There are two mechanism by which CMI
operates
1-By helping phagocytosis
• 2-By releasing cytotoxic substances
Acquired
• Produced actively by host .
• Immunologic memory.
• Negative phase
Passive
• No host required.
• No memory.
• No negative phase .

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Immunity

  • 2. • Immunity referred to the resistance exhibited by the host towards injury cauesd by microorganism and their products. • Protection against dieases is only one of the many consequence of immune response. • There are two types of immunity : 1:Innate immunity 2:Acquired immunity, Funtionally, an immune response can be divides into two related activites –recognition and response.
  • 3. Innate immunity • It is inborn capacity of the body to resist pathog- ens. It eliminates them before development of any disease It is also called non specific or natural immunity, although its efficacy improves when pathogens enters in the body. The cell that mediate immunity are neutrophils, macrophage, natural killer and large lymphocyte.
  • 4. Acquired immunity • It acquires during life and clear from innate immunity. • It is of two types-Active and Passive immunity • Active –It is resistance developed by an individual as a result of an antigenic stimulus. It is either natural or artificial. • Passive - the resistance that is transmitted to a recipient in a readymade form
  • 5. Humoral (acquired) • It is expressed through circulating proteins called antibody • Antibodies are gammaglobulins and are developed by B lymlphocytes. • The mloecule that induced antibody called anitgens .
  • 6. Cell mediated (acquired) • It is generally invoked for dealing with organism which prefers to stay with in the host cells. • It is expressed by large lymphocytes known as T lymphocytes. • There are two mechanism by which CMI operates 1-By helping phagocytosis
  • 7. • 2-By releasing cytotoxic substances
  • 8. Acquired • Produced actively by host . • Immunologic memory. • Negative phase Passive • No host required. • No memory. • No negative phase .