Over 30 pharmaceutical-standard clinical trials and studies prove FlexNow® with 100% SheaFlex70™ has a statistically significant and clinically meaningful impact on joint care and management. Our experience includes human, double-blind, placebo-controlled university hospital clinical trials. Studies you can trust, by professionals you can trust.

1. FlexNow ® with 100% SheaFlex70 TM FlexNowppt081509b brought to you by BSP Pharma Inc.

12. Joint Structure FlexNowppt081509b cartilage Joint capsule (ligaments) bone bone muscle synovial fluid tendon synovial tissue

13. Stages of Osteoarthritis FlexNowppt081509b

15. FlexNowppt081509b Cytokines drive inflammation in the body, can ramp up 1,000 fold when activated, often resulting in a destructive inflammation cascade

17. Joint Structure FlexNowppt081509b cartilage Joint capsule (ligaments) bone bone muscle synovial fluid tendon synovial tissue

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27. HTSNE and Dexamethasone ( steroid ) produce similar Arthritis Clinical Scores : Controls Arthritis FlexNowppt081509b High Triterpene Shea Nut Extract: Screening for Effect on Rat; Type II Collagen Arthritis. Jorgensen JD, Weidner MS. Unpublished pharmacological report. April 10, 2003 Level of statistical significance: * p<0.0001, Mann-Whitney U test

28. FlexNowppt081509b Level of statistical significance: * p<0.0001, Mann-Whitney U test *HTSNE = High Triterpene Shea Nut Extract HTSNE and Dexamethasone ( steroid ) exhibit similar infammation reduction properties: Reduces inflammation

29. HTSNE and Dexamethasone ( steroid ) exhibit similar infammation reduction properties: Reduces inflammation by 9-times FlexNowppt081509b Level of statistical significance: **** p<0.0001, Mann-Whitney U test BSP 201 Screening for Antiinflammatory effect in the Rat-carrageenin induced paw edema assay. Jorgensen JD, Weidner MS. Unpublished pharmacological report. Dec. 20, 2002

31. HTSNE and Ibuprofen produce differentiated Stomach and Intestinal Ulcers/Damage profiles: No gastrointestinal damage FlexNowppt081509b Level of statistical significance: * p<0.0001, Mann-Whitney U test *HTSNE = High Triterpene Shea Nut Extract

32. HTSNE : Exercise Induced Pain and Inflammation Trial with Visual Analog Scale (VAS): Significantly reduces pain and inflammation FlexNowppt081509b A Double-Blind Randomized Placebo Controlled Parallel Group Study Demonstrates Analgesic Effects of Sheanut Oil Extract [BSP-201] in Exercise Induced Muscle Tenderness. Srendt-Nielsen L, Rosetzsky A, Weidner MS. Sept 15, 2003 *HTSNE = High Triterpene Shea Nut Extract

33. HTSNE : Better than Analgesics and GS – Significantly reduces pain and inflammation FlexNowppt081509b A Double-Blind Randomized Placebo Controlled Parallel Group Study Demonstrates Analgesic Effects of Sheanut Oil Extract [BSP-201] in Exercise Induced Muscle Tenderness. Srendt-Nielsen L, Rosetzsky A, Weidner MS. Sept 15, 2003 *HTSNE = High Triterpene Shea Nut Extract

38. FlexNowppt081509b Shea nut harvesting in Burkina Faso, Ghana, and the Ivory Coast

39. FlexNowppt081509b