for OD students .

2. Central Retinal Vein Occlusion
PRESENTED TO
OD students of 5
semester
pef university college
by kausar Ali

3.  When blood vessels to the retina are
blocked it is known as a retinal vein occlusion
or ‘eye stroke’,
 A retinal vein occlusion is a blockage of the
blood vessels that feed the retina, and can
result in sudden and serious vision problems.

4.  The central retinal vein is the venous
equivalent of the central retinal artery and, like
that blood vessel, it can suffer
from occlusion (central retinal vein occlusion,
also CRVO), similar to that seen in ocular
ischemic syndrome. Since the central retinal
artery and vein are the sole source of blood
supply and drainage for the retina, such
occlusion can lead to severe damage to the
retina and blindness, due
to ischemia (restriction in blood supply)
and edema(swelling).

5.  It can also cause
 glaucoma.
 sudden blindness.
 Nonischemic CRVO is the milder form of the
disease. It may progress to the more severe
ischemic type

6.  Treatment consists of Anti-VEGF ( Vascular
endothelial growth factor )drugs
like Lucentis or intravitreal steroid implant
(Ozurdex) and Pan-Retinal Laser
Photocoagulation usually. Underlying
conditions also require treatment. Non-
Ischemic CRVO has better visual prognosis
than Ischemic CRVO.

7.  A systematic review studied the effectiveness
of the anti-VEGF drugs
ranibizumab and pagatanib sodium for
patients suffering from non-ischemic CRVO.
Though there was a limited sample size,
participants in both treatment groups showed
improved visual acuity over 6 month periods,
with no safety concerns.