Keynote delivered at the occasion of the WDP event "Trends in logistics 2020. Opportunities or threats?" ("Logistieke trends 2020. Kans of bedreiging?") on October 16th, 2013 during the "Transport & Logistics 2013" fair in Antwerp (Belgium). The presentation was intended to tease the audience to assess future challenges. It built upon a series of examples of today's changing world in view of challenging futures.