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Oncomine Myeloid GX NGS Solution Infographic
1.
Oncomine Myeloid Assay
GX One-day genomic profiling for myeloid samples For Research Use Only. Not for use in diagnostic procedures. © 2020 Thermo Fisher Scientific Inc. All rights reserved. All trademarks are the property of Thermo Fisher Scientific and its subsidiaries unless otherwise specified. COL013171 0920 * Specimen-to-report workflow will be available after the Ion Torrent™ Genexus™ Purification System and integrated reporting capabilities are added in 2021. Automated specimen-to-report workflow Key features ✓ Whole blood ✓ Peripheral blood leukocytes (PBLs) ✓ Bone marrow Rapid turnaround Results in 1 day to help provide critical answers fast Comprehensive panel of biomarkers DNA mutations and RNA fusion transcripts with one assay Highly automated 10 minutes of hands-on time, 2 user touchpoints Ability to detect challenging targets Dedicated software and excellent gene coverage Integrated reporting Fully annotated variant report Flexible batching Sequence 1–8 samples at once ✓ Automated specimen-to-report workflow, including library preparation, sequencing, variant calling, and reporting* Ion Torrent™ Genexus™ System Ion Torrent™ Oncomine™ Reporter ➡ ➡ ✓ Annotated variant report with biomarkers linked to relevant evidence from public data sources Simultaneously interrogate DNA mutations and RNA fusion transcripts covering all major myeloid disorders: AML, MPN, MDS, CMML, and JMML ✓ 40 total genes 23 hotspot genes 17 full genes ✓ 29 RNA fusion drivers 600 fusion isotypes ✓ 5 gene expression genes ✓ 5 gene expression control genes FLT3-ITD PML-RARA CEBPA IDH1/2 MLLT3 SETBP1 SH2B3 SF3B1 ZRSR2 BCOR TET2 CSF3R CBL NRAS MPL NF1 NPM1 FTL3-TKD PAX5-JAK2 CALR STAG2 ASXL1 TP53 JAK2 WT1 BCR-ABL RUNX1 NRAS U2AF1 PTPN11 RUNX1-RUNX1T1 ETV6 KRAS KIT KMT2A DNMT3A
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