HD Genome One Research Edition is a powerful and intuitive software which enables the visualization, analysis, and interpretation of data obtained from Next-generation Sequencing (NGS).

1. Gonzalo R. Ordóñez, PhD
VP & Chief Science Officer
gonzalo.ordonez@dreamgenics.com
Juan Ron
Senior Account Executive
juan.ron@dreamgenics.com
+34 600 000 968
+34 902 423 023
info@dreamgenics.com
www.dreamgenics.com
Research Edition
HD GENOME ONE

2. Research Edition
HD GENOME ONE
Research Explorer
· Different advanced visualizations by output type.
· Each visualization offering customizable configurations.
· Advanced filter of results.
· Different formats for data exportation.
Research Edition
HD GENOME ONE
Web Manager
HD Genome One Research Station
DREAMgenics provides a data analysis station based
on NGS technologies with our pre-installed and ready
to use HD Genome One Research Edition.
This integrated HARDWARE/SOFTWARE
product provides all the answers to your
laboratory’s needs, both in processing
terms and storage.
All with the high power and quality of the analysis
offered by our HD Genome One Research Edition.
HD Genome One Research Edition is available in two
versions:
· Desktop Tower: for installation in your lab or office.
· Rack: enabling our solutions to be integrated into
your existing infrastructure.
[4] Quesada et al. (2011)
Exome sequencing identifies recurrent
mutations of the splicing factor SF3B1
gene in chronic lymphocytic leukemia.
Nature Genetics 44: 47-52.
[2] Ramsay AJ et al. (2013)
POT1 mutations cause telomere
dysfunction in CLL.
Nature Genetics 45(5):526-30
[1] Robles-Espinoza CD et al. (2014)
POT1 loss-of-function variants predispose
to familial melanoma.
Nature Genetics 46: 478-481
References
HD Genome One Research Edition
HD Genome One Research Edition is a powerful and intuitive software which enables the visualization,
analysis, and interpretation of data obtained from Next-generation Sequencing (NGS).
It is a flexible solution which allows automated analysis of
data depending on the specific needs of each researcher,
providing personalized and visually enriched results.
Main characteristics:
· Supports various input formats.
· Allows different pipelines* to be implemented.
· Personalized analysis parameters.
· Configurable visualization of results.
* Exome, Transcriptome, Gene panels…
About DREAMgenics
Our aim at DREAMgenics is the
clinical application of
g e n o m i c a n d
b i o i n f o r m a t i c
advances.
Our services and
products have been
designed and developed along with
highly prestigious international
research groups and doctors,
including Dr. Carlos López Otín, from
the University of Oviedo.
DREAMgenics scientific division has
taken part in international genome
and sequencing consortiums, being
responsible for the sequencing and
characterization of non-previously
described genomes. DREAMgenics
analyses are then supported by its
research experience, displayed in
numerous scientist publications
(Nature, Nature Genetics, AJHG, etc).
[5] Puente et al. (2011)
Exome sequencing and functional analysis
identifies BANF1 mutation as the cause
of a hereditary progeroid syndrome.
Am. J. Hum. Genet. 88: 650-656.
[3] Puente et al. (2011)
Whole-genome sequencing identifies
recurrent mutations in chronic
lymphocytic leukaemia.
Nature 475: 101-105.
FINAL
REPORT
QUALITY
CONTROL
+
FILTERING
VARIANTS
DETECTION
VARIANTS
FILTERING
ANNOTATION OF
HIGH QUALITY
VARIANTS
MULTIPLE
PLATFORMS
Research Edition
HD GENOME ONE
Pipeline Server
· Design and execution of pipelines.
· Control and parallelization of processes.
· Access to and storage of results.
· Multiple annotation databases.
· Remote control of the analysis process through the web.
· Visual management of pipelines offering multiple
parameter configurations.
· Visualization of execution’s results.
PROPRIETARY
DATABASES
STORAGE
[6] Valdés-Mas et al. (2012)
Estimation of copy number alterations
from exome sequencing data.
PLoS One. 7(12):e51422
Research Edition
HD GENOME ONE
Research Explorer
Research Edition
HD GENOME ONE
Web Manager
BACKUP
Research Station
HD GENOME ONE
STORAGE SYSTEM
Technical specifications :
· CPU: 4 x 10C E5-4650V2 2.4G 25M 8GT/s
· RAM: 256 GB (Up to 1 TB)
· STORAGE: 36 TB (Up to 180 TB)
· OPERATING SYSTEM: 64bit Linux
HDGenome
One Research
Station
·C
O
NNECT AND A
N
ALYZE·