There are several things fundamentally wrong in this illustration. Point out two of them. Point them out, describe why they are wrong, and what they were supposed to be. You can look up anything (especially the lecture 12). size or shape of illustration do not apply (e.g. RNA primer looks like only a few bases, but that is okay, or Helicase is triangular, but that is fine, too). Solution 1: Since lagging strand is discontinuously synthesized in form of Okazaki fragments, RNA primer serve to form primer for synthesis of each of these fragments. So, RNA primer should be located adjacent to the DNA pol at lagging strand. 2: DNA pol alpha serve to form RNA/DNA primers for lagging strand synthesis. These primers are then exptended by DNA pol delta. At lagging strand, only DNA pol alpha is shown..

1. There are several things fundamentally wrong in this illustration. Point out two of them. Point
them out, describe why they are wrong, and what they were supposed to be. You can look up
anything (especially the lecture 12). size or shape of illustration do not apply (e.g. RNA primer
looks like only a few bases, but that is okay, or Helicase is triangular, but that is fine, too).
Solution
1: Since lagging strand is discontinuously synthesized in form of Okazaki fragments, RNA
primer serve to form primer for synthesis of each of these fragments. So, RNA primer should be
located adjacent to the DNA pol at lagging strand.
2: DNA pol alpha serve to form RNA/DNA primers for lagging strand synthesis. These primers
are then exptended by DNA pol delta. At lagging strand, only DNA pol alpha is shown.