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Radiological Findings of
2019-nCoV Pneumonia
PMH Experience
Prepared by Dr SK Li and & Dr YC Lee
Department of Radiology
Caritas Medical Centre/ North Lantau Hospital/ Princess
Margaret Hospital/ Yan Chai Hospital
10 Feb 2020
For internal circulation only
by COC(Rad)
• Reviewed the first 9 thoracic CXR and CT scans of the confirmed
patients with 2019-nCoV pneumonia
• Summarized the findings and observed a pattern
2
CXR findings are non-specific
3
Findings in common:
• Bilateral air-space opacities/ infiltrates
• No pleural effusion
4
The Key +ve CT Findings
1. Ground-glass opacities (100%)
2. Involvement of multiple lobes (100%)
3. Subpleural or peripheral distribution (often central-sparing) (100%)
4. Consolidations (77.8%)
5. Septal thickening (55.6%)
6. Bronchial dilation and wall thickening (55.6%)
5
The Important –ve CT Findings
1. Pleural effusion (0%)
2. Lymphadenopathy (0%)
3. Lung nodule (0%)
4. Specific zonal predominance (variable)
6
Patient demographics and imaging features
Total scans included 9
Age 63.7 (39-75)
Sex
Male 6
Female 3
Days from diagnosis to CT 2.8 (39-75)
CT technique
HRCT 7
Conventional CT 2
CT findings
GGO 9 (100%)
All lobes involvement 8 (88.9%)
Upper lobes sparing 1
Peripheral subpleural distribution 9 (100%)
Zonal predominance
Upper 3 (33.3%)
Basal 3 (33.3%)
Diffuse 3 (33.3%)
Interlobular/ intralobular septal thickening 5 (55.6%)
Consolidation 7 (77.8%)
Bronchial wall thickening or dilatation 5 (55.6%)
Centrilobular nodule 0 (0%)
Pleural effusion 0 (0%)
Lymph node enlargement 0 (0%)
Age and days expressed in means with range in brackets
CT findings expressed in case number with proportions in brackets
7
Examples
8
Ground-glass opacities (GGO)
9
Ground-glass opacities (GGO)
10
Ground-glass opacities (GGO)
11
Ground-glass opacities (GGO)
12
Involvement of multiple lobes
• Often more than one lobes (if not all) show GGO +/- consolidations
13
Involvement of multiple lobes
14
Involvement of multiple lobes
15
Peripheral/ subpleural distribution
• Peripheral/ subpleural regions are
almost invariably involved
• Central regions are often spared/ or
involved in a later stage
16
Peripheral/ subpleural distribution
• Peripheral/ subpleural regions are
almost invariably involved
• Central regions are often spared/ or
involved in a later stage
17
Peripheral/ subpleural distribution
• Peripheral/ subpleural regions are
almost invariably involved
• Central regions are often spared/ or
involved in a later stage
18
Peripheral/ subpleural distribution
19
Consolidations
20
Consolidations
21
Consolidations
22
Consolidations
23
Septal thickening
24
Septal thickening
25
Septal thickening + GGO  crazy-paving pattern
26
Septal thickening + GGO  crazy-paving pattern
27
Bronchial dilatation + wall thickening
28
Bronchial dilatation + wall thickening
29
The Important –ve CT Findings
1. Pleural effusion (0%)
2. Lymphadenopathy (0%)
3. Lung nodule (0%)
4. Specific zonal predominance (variable, upper/basal/diffuse
distribution each 33.3%)
30
Why imaging is important
• There have been reports of cases with serial –ve PCR test results
ending up +ve later
• Typical CT findings in combination of suspicious clinical findings probably
warrant management as potential carriers even if PCR tests show –ve results
• Community outbreak is inevitable
• Some outpatient/ routine scans may be performed for other indications
• If typical nCoV CT findings are seen, these reports require early attention and
possible further investigations ASAP
31
What’s next for Radiology
• Progress CT findings for different clinical courses including improving,
worsening, critical cases
• Follow-up CT findings for patients with prior infection to monitor
pulmonary sequalae
• Work in close collaboration with clinicians down the road
32
Special thanks
• To our PMH Infectious Disease team members who are working under
great risk in managing the isolated patients and providing us with
invaluable clinical information
33

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Radiological findings of 2019 n cov pneumonia

  • 1. Radiological Findings of 2019-nCoV Pneumonia PMH Experience Prepared by Dr SK Li and & Dr YC Lee Department of Radiology Caritas Medical Centre/ North Lantau Hospital/ Princess Margaret Hospital/ Yan Chai Hospital 10 Feb 2020 For internal circulation only by COC(Rad)
  • 2. • Reviewed the first 9 thoracic CXR and CT scans of the confirmed patients with 2019-nCoV pneumonia • Summarized the findings and observed a pattern 2
  • 3. CXR findings are non-specific 3
  • 4. Findings in common: • Bilateral air-space opacities/ infiltrates • No pleural effusion 4
  • 5. The Key +ve CT Findings 1. Ground-glass opacities (100%) 2. Involvement of multiple lobes (100%) 3. Subpleural or peripheral distribution (often central-sparing) (100%) 4. Consolidations (77.8%) 5. Septal thickening (55.6%) 6. Bronchial dilation and wall thickening (55.6%) 5
  • 6. The Important –ve CT Findings 1. Pleural effusion (0%) 2. Lymphadenopathy (0%) 3. Lung nodule (0%) 4. Specific zonal predominance (variable) 6
  • 7. Patient demographics and imaging features Total scans included 9 Age 63.7 (39-75) Sex Male 6 Female 3 Days from diagnosis to CT 2.8 (39-75) CT technique HRCT 7 Conventional CT 2 CT findings GGO 9 (100%) All lobes involvement 8 (88.9%) Upper lobes sparing 1 Peripheral subpleural distribution 9 (100%) Zonal predominance Upper 3 (33.3%) Basal 3 (33.3%) Diffuse 3 (33.3%) Interlobular/ intralobular septal thickening 5 (55.6%) Consolidation 7 (77.8%) Bronchial wall thickening or dilatation 5 (55.6%) Centrilobular nodule 0 (0%) Pleural effusion 0 (0%) Lymph node enlargement 0 (0%) Age and days expressed in means with range in brackets CT findings expressed in case number with proportions in brackets 7
  • 13. Involvement of multiple lobes • Often more than one lobes (if not all) show GGO +/- consolidations 13
  • 16. Peripheral/ subpleural distribution • Peripheral/ subpleural regions are almost invariably involved • Central regions are often spared/ or involved in a later stage 16
  • 17. Peripheral/ subpleural distribution • Peripheral/ subpleural regions are almost invariably involved • Central regions are often spared/ or involved in a later stage 17
  • 18. Peripheral/ subpleural distribution • Peripheral/ subpleural regions are almost invariably involved • Central regions are often spared/ or involved in a later stage 18
  • 26. Septal thickening + GGO  crazy-paving pattern 26
  • 27. Septal thickening + GGO  crazy-paving pattern 27
  • 28. Bronchial dilatation + wall thickening 28
  • 29. Bronchial dilatation + wall thickening 29
  • 30. The Important –ve CT Findings 1. Pleural effusion (0%) 2. Lymphadenopathy (0%) 3. Lung nodule (0%) 4. Specific zonal predominance (variable, upper/basal/diffuse distribution each 33.3%) 30
  • 31. Why imaging is important • There have been reports of cases with serial –ve PCR test results ending up +ve later • Typical CT findings in combination of suspicious clinical findings probably warrant management as potential carriers even if PCR tests show –ve results • Community outbreak is inevitable • Some outpatient/ routine scans may be performed for other indications • If typical nCoV CT findings are seen, these reports require early attention and possible further investigations ASAP 31
  • 32. What’s next for Radiology • Progress CT findings for different clinical courses including improving, worsening, critical cases • Follow-up CT findings for patients with prior infection to monitor pulmonary sequalae • Work in close collaboration with clinicians down the road 32
  • 33. Special thanks • To our PMH Infectious Disease team members who are working under great risk in managing the isolated patients and providing us with invaluable clinical information 33