This document provides a summary of qualifications and experience for Nadder D. Sahar, Ph.D. It includes her education, earning a Ph.D. in Biomedical Engineering from the University of Michigan focusing on the effects of aging and exercise on bone composition and mechanics. It also outlines her extensive experience in mechanical engineering, biomedical research, and working with laboratory animals.

1. Nadder D. Sahar, Ph.D.
11919 W. Verona Ct; Milwaukee, WI 53227 414-810-6233 nadder@gmail.com
SUMMARY OF QUALIFICATIONS
• Employed innovative problem-solving skills and initiative to independently expand techniques and knowledge
base towards mechanical design and biomedical research
• Extensive education and experience in mechanical engineering, statistics, physiology, micro- and nano-scale
material testing, spectroscopy and micro-computed tomography
• Seven years experience working with laboratory animals and animal/human tissues
• Managed collaborative research efforts and mentored numerous students in research techniques and
experimental design
EDUCATION
University of Michigan, Ann Arbor, MI
Ph.D. Biomedical Engineering February 2009
GPA: 3.91 / 4.00
Thesis Title: Investigating the Effects of Aging and Exercise on Bone Composition
and the Impact of Composition on Mechanical Integrity
Honors: • Regenerative Sciences Training Grant R90-DK071506, 2006-2008
• Best Poster Presentation, Midwest Biomedical Engineering Conference, 2006
M.S.E. Biomedical Engineering May 2004
GPA: 3.97 / 4.00; Specialization in Biomechanics
Research: Kinetic modeling of impact forces and moments at the knee during jump landings
Honors: Department Fellowship, 2002-2003
Northwestern University, Evanston, IL
B.S. Biomedical Engineering June 2000
GPA: 3.56 / 4.00; Specialization in Biomechanics
Honors: • Best Biomedical Engineering Senior Design Project, 2000
• 1st Place, 2000 Engineering Design Competition
• 2nd Place, 1999 Engineering Design Competition
EXPERIENCE
University of Michigan, Ann Arbor, MI
Research Fellow 2009
• Developed new collaborations to pursue studies proposed in my Ph.D. thesis (topics involving
bone adaptation, composition and mechanics)
• Mentored graduate students, guiding development of new hypotheses on bone adaptation
and associated experimental designs
Researcher (collaboration with University of California, Santa Barbara) 2007-2009
• Refined and validated a minimally invasive diagnostic instrument to measure
mechanical properties of bone through soft tissue
• Developed strategies for commercialization of the instrument
Regenerative Sciences Training Program Fellow 2006-2008
• Trained with a multidisciplinary team of engineers, biologists and clinicians in an
NIH-sponsored program designed to speed clinical translation of biomedical research
• Strengthened knowledge of intellectual property, technology transfer and patents; clinical trials and FDA
compliance; startup companies and funding sources
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2. Graduate Student Research Assistant 2003-2008
• Conducted thesis research on the influence of exercise and aging on bone’s biochemical
properties and mechanical integrity
• Trained and advised undergraduate and graduate students assisting with thesis-related projects
• Developed new experimental techniques; refined and automated time-consuming analyses
UOP, LLC., Des Plaines, IL
Design Engineer 2000-2002
• Independently designed reactors and internal components for petroleum refinement
• Analyzed flow, pressure distribution, stress and thermal expansion
• Devised novel designs for custom retrofitting of reactors
• Supervised international crew of 20 members during installation of components
Marquette University, Milwaukee, WI
Research Assistant 1999
• Designed and built a device for pressure distribution testing of knee implants at various flexion angles
ACTIVITIES
• Built a passive-dynamic walking robot, Medical University of South Carolina 2010
• Trekked to Mt. Everest Base Camp in Nepal 2009
• Incorporated a nonprofit company to raise funds for leukemia research 2009
• Graduate Student Mentor, University of Michigan 2005-2008
• Graduate Vice President, Biomedical Engineering Society, University of Michigan 2003-2004
• Chicago Cares Volunteer and Project Leader 2000-2002
• Hobbies: ice hockey, photography, adventure travel
SKILLS
• Wide-ranging laboratory experience, which includes mechanical testing, nanoindentation, laser scanning
confocal microscopy and micro-computed tomography
• Extensive experience working with laboratory mice and tissues: handling, injections, dissection, sterile
techniques and histological sample preparation
• SPSS and statistical techniques, including advanced regressions
• Programming: Matlab, Labview, C, C++, Visual Basic, Fortran, Pascal
• Drawing and image creation with AutoCAD, Microstation, Adobe Illustrator and Photoshop
• Design and fabrication of devices for use in research
PEER-REVIEWED PUBLICATIONS
Sahar, ND, K Golcuk, MS Ron, SR Obreiter, DH Kohn, “Exercise Improved Tissue Strength, Fatigue Resistance,
and Mineral Composition of Pre-Existing Tissue in Murine Tibiae,” (in review)
Raghavan, M, ND Sahar, RH Wilson, M Mycek, N Pleshko, DH Kohn, MD Morris, “Quantitative Polarized
Raman Spectroscopy in Highly Turbid Bone Tissue,” (in review)
Sahar, ND, K Golcuk, MD Morris, LA Winkel, DH Kohn, “Aging Decreased Mechanical Properties of Bone by
Compromising Tissue Quality, not Quantity, in Murine Tibiae,” (in review)
Sahar, ND, M Raghavan, MD Morris, DH Kohn, “Compositional Changes of Bone Mineral and Matrix Have
Correlations with Mechanical Properties that May Depend on Bone Age and Initial Composition,” (in review)
Xu, J, P Zhu, Z Gan, N Sahar, M Tecklenburg, M Morris, D Kohn, A Ramamoorthy, “Natural-Abundance 43Ca
NMR and Raman Spectroscopy of Bone,” (in review)
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3. Raghavana, M, ND Sahar, RH Wilson, M Mycek, N Pleshko, DH Kohn, MD Morris, “Polarized Raman
Spectroscopy of Bone Tissue: Watch the Scattering,” (in review)
Ramamoorthy, A, J Xu, P Zhu, Z Gan, N Sahar, M Morris, M Tecklenburg, D Kohn, “Probing the Structure of
Calcium Sites in Bone Mineral by Natural-Abundance 43Ca Solid-State NMR Spectroscopy,” (in review)
Randall, C, P Mathews, E Yurtsev, N Sahar, D Kohn, P Hansma, “The Bone Diagnostic Instrument III: Testing
Mouse Femora,” Review of Scientific Instrumentation 80(6): 065108 (2009)
Zhu, P, J Xu, M Morris, N Sahar, D Kohn, A Ramamoorthy, “Quantum Dots as Mineral- and Matrix-Specific
Strain Gauges for Bone Biomechanical Studies,” Proceedings of SPIE 7166: 71660F (2009)
Kohn, DH, ND Sahar, JM Wallace, K Golcuk, MD Morris, “Exercise Alters Mineral and Matrix Composition in
the Absence of Adding New Bone,” Cells Tissues Organs 189: 33-37 (2009)
Raghavan, M, MD Morris, ND Sahar, DH Kohn, “Polarized Raman Spectroscopy: Application to Bone
Biomechanics,” Proceedings of SPIE 6853: 68530W (2008)
Hansma P, P Turner, B Drake, E Yurtsev, A Proctor, P Mathews, J Lelujian, C Randall, J Adams, R Jungmann, F
Garza-de-Leon, G Fantner, H Mkrtchyan, M Pontin, A Weaver, MB Brown, N Sahar, R Rossello, D Kohn, “The
Bone Diagnostic Instrument II: Indentation Distance Increase,” Review of Scientific Instrumentation 79(6): 064303
(2008)
Golcuk, K, GS Mandair, AF Callender, WF Finney, ND Sahar, DH Kohn, MD Morris, “Rapid Raman
Spectroscopy of Musculoskeletal Tissue Using a Visible Laser and an Electron-Multiplying CCD (EMCCD)
Detector,” Proceedings of SPIE 6093: 609314 (2006)
Golcuk, K, GS Mandair, AF Callender, ND Sahar, DH Kohn, MD Morris, “Is Photobleaching Necessary for
Raman Imaging of Bone Tissue Using a Green Laser?” Biochim. Biophys. Acta 1758: 868-873 (2006)
Kohn, DH, ND Sahar, SI Hong, K Golcuk, MD. Morris, “Local Mineral and Matrix Changes Associated with
Bone Adaptation and Microdamage,” Proceedings of the Materials Research Society 898E: 1-11 (2006)
Sahar, ND, SI Hong, DH Kohn, “Micro- and Nano-Structural Analyses of Damage in Bone,” Micron 36: 617-629
(2005)
Callender, AF, WF Finney, MD Morris, ND Sahar, DH Kohn, KM Kozloff, SA Goldstein, “Dynamic Mechanical
Testing System for Raman Microscopy of Bone Tissue Specimens,” Vibrational Spectroscopy 38: 101-105 (2005)
PRESENTATIONS
Sahar, ND, M Raghavan, M Morris, DH Kohn, “Compositional Changes of Bone Mineral and Matrix Have
Correlations with Mechanical Properties that May Depend on Bone Age,” Annual Meeting of the Orthopaedic
Research Society, New Orleans, LA (March 2010)
Sahar, ND, K Golcuk, MD Morris, DH Kohn, “Bone Composition as the Primary Mechanism for Increased
Skeletal Fragility and Decreased Adaptation in Old Mice,” Annual Meeting of the Orthopaedic Research Society,
San Francisco, CA (February 2008)
Sahar, ND, SR Obreiter, MS Ron, LA Winkel, DH Kohn, “Effects of Exercise and Age on Bone Tissue Quality,”
Midwest Tissue Engineering Consortium, Ann Arbor, MI (April 2007)
Golcuk, K, ND Sahar, MD Morris, DH Kohn, “Raman Mircrospectroscopic Study of Compositional Changes in
Microdamaged Bone,” Annual Meeting of the Orthopaedic Research Society, San Diego, CA (February 2007)
Sahar, ND, MS Ron, SR Obreiter, DH Kohn, “Exercise Improves Composition and Mechanical Integrity in
Murine Tibiae,” Midwest Biomedical Engineering Conference, Ann Arbor, MI (March 2006)
Sahar, ND, DH Kohn, K Golcuk, MD Morris, “Effects of Exercise on Bone Quality as Shown by Raman
Microspectroscopy,” Annual Meeting of the Orthopaedic Research Society, Chicago, IL (February 2006)
Sahar, ND, MS Ron, SR Obreiter, DH Kohn, “Exercise Increases Pre-Yield Mechanical Properties and Damage
Resistance in Murine Tibiae,” Annual Meeting of the Orthopaedic Research Society, Chicago, IL (February 2006)
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