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Costella Resume June 2015


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Costella Resume June 2015

  1. 1. Lauren Costella 141 Brookwood Dr  Charlottesville, VA 22902  (804) 543-6755  ASSOCIATE SCIENTIST Biomaterials  Electrospinning  Wound Healing  Proposal Writing  Project Management Proven success obtaining funding and managing the technical aspects of early-stage research and development programs. Key achievements include:  Initiation of an electrospinning program: generating nanofibers for protein purification, sample stabilization, wound healing, and drug delivery purposes.  Generation of original research ideas in various areas of wound healing, tissue regeneration, drug delivery, and protein purification processing followed by successful submission of SBIR proposals and management of technical programs in these areas.  Successful communication with product end-users and technical collaborators to ensure development of commercially relevant wound-healing products. Education University of Virginia -- Charlottesville, VA Masters of Engineering, Materials Science and Engineering, 2015 Bachelors of Science, Biomedical Engineering, 2009 Experience LUNA INNOVATIONS -- Charlottesville, VA – 2009-present Biomedical Research Technician  Biomedical Research Associate  Biomedical Associate Scientist Program Management • Managed the technical aspects of programs in ocular wound healing, therapeutic drug delivery, adhesion prevention, and protein purification • Mentored summer interns and senior Capstone students Proposal Writing and Funding Generation • Generated original research ideas in response to both Department of Defense solicitations and recognized voids in the medical community • Won more than 50% of submitted proposals (national average ~12%) • Brought in over $2.6 million worth of federal funding Electrospinning • Established an electrospinning program at Luna, which has since led to more than $4 million worth of company funding • Mastered fabrication of nanofiber samples using the NanoSpider NS Lab System
  2. 2. Lauren Costella (804) 543-6755  Page 2 • Characterized loading and release profiles of encapsulated therapeutics in nanofiber-based dressings Wound Healing • Worked with practicing physicians to adapt a solid barrier film into a sprayable hydrogel for adhesion prevention • Initiated a group area of expertise in ocular wound healing, developing bandages for sutureless application and closure of open-globe injuries • Managed the technical efforts of a program delivering analgesics to burn wounds in a controlled manner Materials Science • Skilled in the functionalization and characterization of biopolymers • Experienced in biomaterial characterization, including FTIR, UV-Vis spectrophotometry, and viscometry Professional Communication • Wrote technical progress reports, proposals, and invention disclosures • Presented research efforts on the sprayable adhesion barrier to LifeCell Corporation • Conducted conference poster presentations on ocular wound healing and sprayable adhesion barrier research efforts • Assisted with the development, marketing, and sales of TrueClot®, a simulated blood product for medic training • Represented Luna Innovations at college research and career fairs • Managed IP for the entire Technology Development Division, serving as liaison between the lawyers and the researchers. Research Internships LUNA INNOVATIONS – Charlottesville, VA Capstone Thesis Project, 2008 – 2009 Developed a porous bone scaffold to prevent infection and promote natural bone growth in critically sized defects; Determined elution rates of simulated growth factors and antimicrobials from the scaffold. UNIVERSITY OF VIRGINIA HOSPITAL – Charlottesville, VA Research Intern – Department of Radiation Oncology, 2008 Wrote MATLAB and LabView programs using functions to mimic the motion of a lung tumor during a breathing cycle; Used the NI Motion Control program to execute and test various motion profiles ETHICON INC. -- Somerville, NJ Research Intern, Women’s Health Department, 2007 Assisted with laboratory testing and product development for the Gynecare ThermaChoice uterine ablation device; Performed simulated ablation treatments on beef tongue and calculated the resultant depth of necrosis using ImageJ; Developed a protocol to determine the flow rate in the uterine ablation catheter.
  3. 3. Lauren Costella (804) 543-6755  Page 3 Presentations Costella, L.A, Pineros-Fernandez, A.C, Rodeheaver, G.T, Danilich, M.J, Cottler, P.S. (2013). “The Efficacy of a Novel, Sprayable Biopolymer Barrier in the Prevention of Postoperative Adhesions.” Presented at the Society of American Gastrointestinal and Endoscopic Surgeons Annual Meeting, Salt Lake City, UT, April 2014. Costella, L.A, Eiseman, A., Tison, C.K. (2015). “Development of Biomimetic Materials for Sutureless Ocular Surface Repair.” Presented at the Society for Biomaterials Annual Meeting, Charlotte, NC, April 2015. Costella, L.A., Eiseman, A., Tison, C.K. (2015) “Nanofiber Reinforced Hydrogel Dressings for Ocular Wound Healing” Military Health Science Research Symposium. Poster. Fr. Lauderdale, FL. August 2015. Skills and Technology (extended list on request) Electrospinning, Cell Culture, SDS-PAGE, Tensile Testing, Viscometry, FTIR Characterization, Chemical Modification of Materials, Animal Tissue Testing Proficient in Excel, MATLAB, ImageJ; Experienced with LabView, MiniTab, and AUTOCAD Affiliations Society for Biomaterials  Materials Research Society  Biomedical Engineering Society Available for Nationwide or International Relocation