1. C urriculum Vitae
A llergan, Inc .
Formulation S c ientist
Small Molecule Produc t Development
2525 Dupont Drive
Irvine, C A 92612
Kumar_Sumit@Allergan.com
Sumit Kumar
EDUCATION
2009-2014: University of Connecticut, Storrs, CT — PhD (Pharmaceutics)
2006-2009: Southern Illinois University, Springfield, IL — Master of Science (Pharmacology)
2001-2005: College of Pharmacy, Delhi University, India— Bachelor of Pharmacy
PROFESSIONAL EXPERIENCE
Late Stage Formulation Scientist, Allergan, Inc. Irvine, CA — 04/2013 -CURRENT
Summer internship: Boehringer Ingelheim Pharmaceutical Inc. Ridgefield, CT — 05/2011~08/2011
RESEARCH EXPERIENCES
Industry Formulation/Product Experience:
1. Process and formulation development of ophthalmic nano-sized suspensions.
2. Process and formulation development of ophthalmic injectable sustained release formulation.
4. Development of spray drying process of highly viscous solutions and scale-up.
5. Process and product development of ophthalmic topical solution.
6. Formulation of pH-sensitive solid dispersion of poorly soluble drugs for oral bioavailability enhancement.
Ph.D. Research Experience:
1. Media milling for nano-crystalline suspensions.
2. Spray and freeze-drying of nano-crystalline suspensions.
3. Development of nano-amorphous spray-dried formulations of poorly soluble drugs and in vivo performance.
4. Development of pH-controlled oral dosage formulations (i.e. pH-susceptible solid dispersions) of poorly soluble drugs.
5. Formulation design and in vivo performance of amorphous and nano-crystal powders of poorly soluble drugs.
6. Development of dissolution method for nano-particles formulations using USP dissolution apparatus II & IV.
Equipment Familiar With
Netzsch media mill, microfluidizer, spray dryer, Lyostar smart II/III freeze dryer, FTIR, Raman spectrometer, AFM, HPLC, LC-MS,
USP apparatus I/II/IV, DSC, XRD spectroscopy, TGA, dynamic vapor sorption instrument, Karl-Fisher titrimeter, SEM, dynamic
light scattering instrument for particle size analysis, Zetasizer for zeta potential measurement, Brookfield rheometer, tensiometer,
FELLOWSHIPS & AWARDS
• 2012, American Association of Pharmaceutical Scientists (AAPS) Graduate Student IPEC Excipient Award
• 2005-2006, Graduate Fellowship, University Grants Commission (UGC), Delhi 2011
• 2001, Indira Gandhi Award for Excellence in Science, First Position, India
• 2001, Distinctive Performance in National Science Olympiad, India
PUBLICATIONS
Book chapters
1. Kumar, S., Burgess, D.J. Nanosuspensions- controlled release science and technology: In “Controlled Release Science and
Technology: Long Acting Injections and Implants”. Eds. Wright, J. and Burgess, D.J. CRS Press, Springer.
Publications
1. Kumar, S., Shen, J., Zolnik, B., Sadrieh, N., Burgess, D.J. Optimization an dissolution performance of spray-dried naproxen
nano-crystals. (Under review- European Journal of Pharmaceutics and Biopharmaceutics, July 2014).

2. 2. Kumar, S., Jog, R., Shen, J., Zolnik, B., Sadrieh, N., Burgess, D.J. In Vitro and In Vivo Performance of Different Sized Spray-
Dried Crystalline Itraconazole. (Journal of Pharmaceutical Sciences, June 2014).
3. Kumar, S., Jog, R., Shen, J., Zolnik, B., Sadrieh, N., Burgess, D.J. Formulation and Performance of Danazol Nano-crystalline
Suspensions and Spray Dried Powders. (Pharmaceutical Research, November 2014).
4. Kumar, S., Shen, J., Burgess, D.J. A DoE to formulate nano-amorphous spray-dried formulation of poorly soluble compound.
Journal of Controlled Release 2014; 192: 95-102.
5. Kumar, S., Ghokale, R., Burgess, D.J. Mechanistic study to understand the role of different sugars on spray drying of
crystalline nanosuspensions. Int J Pharm 2014; 471(1-2): 303-11.
6. Kumar, S., Lineham, B., Chao, Y.T. A new combination approach of CI jet and QESD to formulate pH-sensitive amorphous
solid dispersion. Int J Pharm 2014; 466(1-2): 368-74
7. Kumar, S., Ghokale, R., Burgess, D.J. QbD approach to spray drying processing of crystalline nanosuspensions. Int J Pharm
2014; 464(1-2): 234-242.
8. Kumar, S., Ghokale, R., Burgess, D.J. Formulation parameters of crystalline nanosuspensions on spray drying processing: A
DoE approach. Int J Pharm 2014; 464(1-2): 34-45.
9. Kumar, S., Burgess, D.J. Wet milling induced physical and chemical instabilities of naproxen nano-crystalline suspension. Int J
Pharm 2014; 466(1-2): 223-232.
10. Verma, S., Kumar, S., Gokhale, R., Burgess, D.J. Physical stability of nanosuspensions: Investigation of stabilizer role on
Ostwald ripening. International Journal of Pharmaceutics. 2011, 406 (1-2): 145-52.
11. Walia, V., Ding, M., Kumar, S., Nie, D., Premkumar, L.S., Elble. R.C. hCLCA2 is a p53-inducible inhibitor of breast cancer cell
proliferation. Cancer Research. 2009, 69(16): 6624-32.
12. Sachdeva, M., Zhu, S., Wu, F., Wu, H., Walia, V., Kumar, S., Elble, R.C., Watabe, K., Mo, Y.Y. p53 represses c-Myc through
induction of the tumor suppressor miR-145. Proceedings of the National Academy of Sciences. 2009, 106(9): 3207-12.
13. Kumar, S., Walia, V., Ray, M., Elble, R.C. p53 in breast cancer: mutation and countermeasures. Frontier Bioscience 2007,
12:4168-78.
Posters
1. Kumar, S., Jog, R., Shen, J., Zolnik, B., Sadrieh, N., and Burgess, D.J. In vitro and in vivo performance of different sized spray-dried
crystalline itraconazole. AAPS Annual Meeting and Exposition 2014, California.
2. Kumar, S., Jog, R., Shen, J., Zolnik, B., Sadrieh, N., and Burgess, D.J. Formulation and performance of danazol Nano-crystalline
suspensions and spray dried powders.
3. Kumar, S., Burgess, D.J. Quality by Design (QbD) approach to formulate nano-amorphous spray dried formulation of poorly
soluble drugs. AAPS Annual Meeting and Exposition 2013, Texas.
4. Kumar, S., Shen, J., Zolnik, B., Sadrieh, N., and Burgess, D.J. Design of experiment (DoE) approach to formulate
nanocrystalline spray dried formulation of poorly soluble drugs. AAPS Annual Meeting and Exposition 2013, Texas.
5. Kumar, S., Burgess, D.J. Physical and Chemical Instability of Poorly Soluble Drugs during Media Milling. A Case Study of
Naproxen-HPMC E15 Nanosuspension. AAPS Annual Meeting and Exposition 2013, Texas.
6. Kumar, S., Burgess, D.J. Mechanistic approach to understand aggregation of nanoparticles during spray drying of
nanosuspensions. AAPS Annual Meeting and Exposition 2012, Chicago.
7. Kumar, S., Linehan, B., Tseng, Y.C. A novel approach to formulate pH-susceptible amorphous microparticles for dissolution
enhancement of BI5906, Chicago. AAPS Annual Meeting and Exposition 2012, Chicago.
8. Kumar, S., Burgess, D.J. Effect of different stabilizers in spray drying of nanosuspensions. AAPS Annual Meeting and
Exposition 2011, Washington D.C.
9. Kumar, S., Burgess D.J. Quality by Design (QbD) approach to understand spray drying of nanosuspensions. AAPS Annual
Meeting and Exposition 2011, Washington D.C.
10. Kumar, S., Burgess D.J. Role of different stabilizers/excipients in spray drying of nanosuspensions. Center for Pharmaceutical
Processing Research 2011, Minneapolis.
11. Verma, S., Kumar, S., Ghokale, R., Burgess D.J. Phsical stability of nanosuspensions: Investigation of the role of stabilizers on
Ostwald ripening. 2010 AAPS Annual Meeting and Exposition, New Orleans.
12. Kumar, S., Burgess, D.J. Quality by design approach to understand the factors involved in dialysis sac method of dissolution.
Center for Pharmaceutical Processing Research 2010, Indianapolis.
13. Kumar, S., Burgess, D.J. Critical parameters involved in spray drying of nanosuspensions. Center for Pharmaceutical
Processing Research 2010, Indianapolis.
14. Walia, V., Kumar, S., Ding, M., Elble, R.C. p53-target gene hCLCA2 inhibits breast cancer cell proliferation. 9th Annual Science
symposium 2009, Southern Illinois University, Springfield, IL.
15. Kumar, S., Elble, R.C. Regulation of hCLCA2 by the PI3K-AKT pathway and its role in anoikis. AACR Meeting 2008.
16. Walia, V., Kumar, S., Ding, M., Elble R.C. p53 is a direct transcriptional regulator of pro-apoptotic hCLCA2. AACR Meeting
2008.
17. Walia, V., Kumar, S., Elble, R.C. Breast cancer tumor suppressor hCLCA2 is induced by p53 and multiple forms of stress.
AACR Meeting 2007.
TEACHING EXPERIENCE
• 2009-2011, Teaching assistant (University of Connecticut)
• Fall 2005, Teaching assistant (College of Pharmacy, Delhi University)

3. EXTRACURRICULAR ACTIVITIES & SERVICE
• Reviewer, International Journal of Pharmaceutics, since 2009 (32 completed assignments)
• Reviewer, BioMed Research International, since 2014 (1 completed assignment)
• Reviewer, Journal of Pharmaceutical Sciences, since 2014 (1 completed assignment)
• Steering committee member, AAPS-Quality by Design and Product Performance Focus group, since 2012
• Editor and Student representative, AAPS-Quality by Design and Product Performance Focus group, Mach’12- Feb’14
• President, AAPS UConn Student Chapter, 2011-2012
• Treasurer, AAPS UConn Student Chapter, 2010-2011
PROFESSIONAL ORGANIZATIONS
• American Association of Pharmaceutical Scientists (AAPS), 2009-to date
KEY GRADUATE COURSES
• Colloid Chemistry and Interfacial Phenomenon
• Kinetics and Mechanism of Drug Degradation: Concepts in Stability and Kinetics of Drugs with emphasis of Proteins
• Transport Processes: Concepts in Diffusion and Flux in Drug Delivery Systems
• Freeze Drying of Pharmaceuticals: Science and Technology of Freeze-Drying with emphasis on Proteins
• Design of Experiment: Statistics
REFERENCES
Available on request