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DIAGNOSTIC VALUE OF
SERUM ENZYMES
CARDIAC BIOMARKERS
CK-MB AST LDH
ENZYME PROFILE IN LIVER DISEASE
ALT
ALP
obstructiv
e
γGT
hepatobili
ary
ALT
 Alanine aminotransaminase
 ↑ in acute liver damage
ALP
 Alkaline phosphatase
 Bone & liver
↑in rickets, hyperparathyroidism, Paget disease, obstructive
jaundice, osteoblastic sarcoma.
γGT
Gamma glutamyl transpeptidase
↑ in hepatobiliary obstruction, alcohol induced liver disease
ALP ↑ in bone disease
ACID PHOSPHATASE ↑ in prostatic carcinoma with
metastasis
CREATINE KINASE(MM) ↑ in muscle disease
AMYLASE ↑ in parotitis, acute pancreatitis
Clinical uses of enzymes, diagnostic importance of enzymes
Clinical uses of enzymes, diagnostic importance of enzymes
Clinical uses of enzymes, diagnostic importance of enzymes
Clinical uses of enzymes, diagnostic importance of enzymes
Clinical uses of enzymes, diagnostic importance of enzymes
Clinical uses of enzymes, diagnostic importance of enzymes
Clinical uses of enzymes, diagnostic importance of enzymes
Clinical uses of enzymes, diagnostic importance of enzymes
Clinical uses of enzymes, diagnostic importance of enzymes
Clinical uses of enzymes, diagnostic importance of enzymes

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Clinical uses of enzymes, diagnostic importance of enzymes

  • 1.
  • 4. ENZYME PROFILE IN LIVER DISEASE ALT ALP obstructiv e γGT hepatobili ary
  • 5. ALT  Alanine aminotransaminase  ↑ in acute liver damage ALP  Alkaline phosphatase  Bone & liver ↑in rickets, hyperparathyroidism, Paget disease, obstructive jaundice, osteoblastic sarcoma. γGT Gamma glutamyl transpeptidase ↑ in hepatobiliary obstruction, alcohol induced liver disease
  • 6. ALP ↑ in bone disease ACID PHOSPHATASE ↑ in prostatic carcinoma with metastasis CREATINE KINASE(MM) ↑ in muscle disease AMYLASE ↑ in parotitis, acute pancreatitis