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LARYNGITIS
Dr.Sayed Muddasir Shah
LARYNGITIS
 Inflammation of the larynx
 Can impair swallowing, phonating and breathing
ACUTE LARYNGITIS
 Phonotrauma
 Viral Laryngitis
 Acute Bacterial Laryngitis
 Acute Fungal Laryngitis
 Supepithelial hemorrhage from phonotrauma
 Supepithelial hemorrhage of R VC polyp
ACUTE LARYNGITIS
 Phonotrauma
 Viral Laryngitis
 Acute Bacterial Laryngitis
 Acute Fungal Laryngitis
VIRAL LARYNGITIS
 Pathogens: rhinovirus,
parainfluenza, RSV, adenovirus,
influenza, adenovirus…
 SSx: dysphonia, hoarse voice,
cough
 Rx: supportive care: hydration,
anti-inflam, voice rest, PPI +/-
steroids
 Croup: laryngotracheobronchitis
 Typically parainfluenza 1,3
 Steeple sign
ACUTE LARYNGITIS
 Phonotrauma
 Viral Laryngitis
 Acute Bacterial Laryngitis
 Acute Fungal Laryngitis
ACUTE BACTERIAL LARYNGITIS
 Supraglottitis (Acute epiglottitis)
 Pathogens: H influenza, Strep PNA,
Staph Aureus, Beta hemolytic strep
 Decreased incidence with h flu B vaccine
 Rx: airway control. Humid air, IV
antibiotics, monitored bed, steroids
ACUTE BACTERIAL LARYNGITIS
 Whooping cough
 bordetella pertusis
 Vaccine protects ~ 3 yrs
 Rx: erythromycin to prevent spread
 Diptheria
 Corynebacterium diptheria
 SSx: acetone breath, thick
grey membranous and friable
plaque
 Rx: airway via trach, diptheria
anti toxins, PCN & clinda
ACUTE LARYNGITIS
 Phonotrauma
 Viral Laryngitis
 Acute Bacterial Laryngitis
 Acute Fungal Laryngitis
ACUTE FUNGAL LARYNGITIS
 Candiasis (moniliasis)
 usually seen with oral/esophageal sx or in a pt taking
oral inhaled steroids
 White sessile plaques on erythematous base
 Rx: Fluconazole
CHRONIC LARYNGITIS
 Bacterial
 Fungal
 Mycobacterial
 Non infectious
CHRONIC BACTERIAL LARYNGITIS
 Rhinoscleroma
 Klebsiella rhinoscleromatosis
 Path: Mikulicz Cells
 Rx: fluouroquinolones/
 Syphillis
 Secondary: painless edema
 Tertiary: gummas + cartil destruction
CHRONIC BACTERIAL LARYNGITIS
 Actinomycosis
 Actinomycosis israelii
 Chronic suppurative infxn, rarely involves layrnx
 Histo:
 Sulfur Granules
CHRONIC LARYNGITIS
 Bacterial
 Fungal
 Histoplasmosis
 Blastomycosis
 Cryptococcus
 Coccidiomycosis
 Mycobacterial
 Non infectious
CHRONIC LARYNGITIS
 Bacterial
 Fungal
 Mycobacterial
 Non infectious
MYCOBACTERIAL LARYNGITIS
 Tubercolosis
 Direct from lungs or via blood
 Dx: PPD/Quant/AFB
 Tx: INH/Rifampin/voice rest
 Leprosy (Hansen’s)
 AFB and granulomas
 Ulcerative supraglottis
 Dx: foamy leprous cells
 Rx: dapsone & CS
CHRONIC LARYNGITIS
 Bacterial
 Fungal
 Mycobacterial
 Non infectious
NON INFECTIOUS LARYNGITIS
 Smoking
 Pollution
 Vocal Abuse
 Rhinosinusitis
 Laryngopharyngeal Reflux
 Wegener’s
Granulomatosis
 Relapsing
Polychondritis
 Sarcoidosis
 Rheumatoid Arthritis
 Pemphigus/pemphigoid
 Amyloidosis
THANKS

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Laryngitis

Editor's Notes

  1. Rx: voice rest and voice therapy, anti inflammatories (ibuprofen)
  2. Pathogens: most common is rhinovirus, but many viruses can cause Croup typically caused by parainfluenza, but also influenza, RSV. Steroids shorten hospitalization. Brassy barky cough, gradual onset. “steeple sign.”
  3. Epiglottitis develops more rapidly and due to a ball-valve effect of the epiglottis, can lead to respiratory failure. Gag can precipitate obstruction -take children to the OR for controlled intubation with possible trach. -usually OK to NP scope adults
  4. Whooping cough: admit kids because they can become apeneic during cough Diptheria: intubation can dislodge membrane into lung, Clinda decreases toxin production (neurotoxin)
  5. DDx for white lesions of the vocal cord: leukoplakia/hyperkeratosis/malignancy/thick mucous/candida Nystatin swish and spit/swallow usually ineffective for the TVC
  6. Mikulicz cells: Gram negative coccobacillus in foamy appearing Macrophages
  7. Histo: branching anaerobic/microaerophillic GN bacteria with sulfur granules Image: before and after PCN
  8. TB lesion: typically posterior glottis (interarytenoid, laryngeal surface of epiglottis, VF) and appears nodular/exophytic/ulcerative Test for HIV