case study presentation - icfai

1. Pfizer - Lipitor
The issue
The track record
Common practice?
Remedies

2. Pfizer – Lipitor The Issue
FDA Approved for cholesterol
above 160 mg
Off label Marketing
Cholesterol >130 mg
Seminars Lipitor Sale
15
(Pfizer sponsored?) research 10
article 5
Sponsored? Research? 0
2000 2001 2002 2003 2004 2005 2006

3. Pfizer – Lipitor The Track record
• Neurontin 1993
– Seizures (original)
– Headaches, Psychiatric
conditions
• In 2009, Paid 1.8 Billion
USD as fines for
– Bextra
– Geodon
– Zyvox
– Lyrica

4. Pfizer - Lipitor Common Practice?
2009 - Pfizer – 1.8 billion USD (4
drugs)
2007 – Astrazeneca – 520 million
USD
seroquel – anti psychotic drug for
children – leads to weight gain and
diabetes
2001 – Eli Lilly – 1.4 billion USD
Zyprexa – anti psychotic drug for
elderly
Promoted off label for dementia
and children in primary care

5. Pfizer – Lipitor - Remedies
Orange book
Corporate Integrity
agreement