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Why Do Some Men
Get Prostate Cancer?
Mr Marc Laniado MD FEBU FRCS(Urol)
Consultant Urological Surgeon
Normal prostate cells can turn into an
uncontrolled growth of cancer cells
Normal cells Cancer cells
Age is the most important
risk factor for prostate cancer
Relatives with prostate or breast
cancer increase the risk
Pancreatic
Prostate
Prostate PancreaticBreast
Breast
ProstateProstate
Ovary
Colon
Some rare genes eg BRCA2
raise risk 7 x for important PCa
Affected: inherited faulty gene from 1 parentUnaffected: inherited 1 normal gene from each parent
`
`
Affected parentUnaffected parent
Gene pair: 1 of pair is faultyGene pair: both normal
`
`
`
`
Black men more likely to get
prostate cancer than Asians
Healthy diet and exercise can
reduce risk of prostate cancer
Why are some men at greater risk for prostate cancer?
Why are some men at greater risk for prostate cancer?

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Why are some men at greater risk for prostate cancer?

  • 1. Why Do Some Men Get Prostate Cancer? Mr Marc Laniado MD FEBU FRCS(Urol) Consultant Urological Surgeon
  • 2. Normal prostate cells can turn into an uncontrolled growth of cancer cells Normal cells Cancer cells
  • 3. Age is the most important risk factor for prostate cancer
  • 4. Relatives with prostate or breast cancer increase the risk Pancreatic Prostate Prostate PancreaticBreast Breast ProstateProstate Ovary Colon
  • 5. Some rare genes eg BRCA2 raise risk 7 x for important PCa Affected: inherited faulty gene from 1 parentUnaffected: inherited 1 normal gene from each parent ` ` Affected parentUnaffected parent Gene pair: 1 of pair is faultyGene pair: both normal ` ` ` `
  • 6. Black men more likely to get prostate cancer than Asians
  • 7. Healthy diet and exercise can reduce risk of prostate cancer