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Essentials of Human Anatomy & Physiology
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
Seventh Edition
Elaine N. Marieb
Chapter 14
The Digestive System
and Body Metabolism
The Digestive System and Body
Metabolism
Slide 14.1
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
 Digestion
Breakdown of ingested food
 Absorption
Passage of nutrients into the blood
 Metabolism
Production of cellular energy (ATP)
Organs of the Digestive System
Slide
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
 Two main groups
 Alimentary canal – continuous coiled hollow
tube
 Accessory digestive organs
Organs of the Digestive System
Slide
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
Figure 14.1
Organs of the Alimentary Canal
Slide 14.3
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
 Mouth
 Pharynx
 Esophagus
 Stomach
 Small intestine
 Large intestine
 Anus
Mouth (Oral Cavity) Anatomy
Slide 14.4
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
 Lips (labia) – protect
the anterior opening
 Cheeks – form the
lateral walls
 Hard palate – forms
the anterior roof
 Soft palate – forms
the posterior roof
 Uvula – fleshy
projection of the
soft palate
Figure 14.2a
Mouth (Oral Cavity) Anatomy
Slide 14.5
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
 Vestibule – space
between lips
externally and teeth
and gums internally
 Oral cavity – area
contained by the
teeth
 Tongue – attached at
hyoid and styloid
processes of the
skull, and by the
lingual frenulum Figure 14.2a
Mouth (Oral Cavity) Anatomy
Slide 14.6
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
 Tonsils
Palatine tonsils
Lingual tonsil
Figure 14.2a
Processes of the Mouth
Slide 14.7
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
 Mastication (chewing) of food
 Mixing masticated food with saliva
 Initiation of swallowing by the tongue
 Allowing for the sense of taste
Pharynx Anatomy
Slide 14.8
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
 Nasopharynx –
not part of the
digestive system
 Oropharynx –
posterior to oral
cavity
 Laryngopharynx –
below the oropharynx
and connected to
the esophagus Figure 14.2a
Pharynx Function
Slide 14.9
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
 Serves as a passageway for air and
food
 Food is propelled to the esophagus by
two muscle layers
Longitudinal inner layer
Circular outer layer
 Food movement is by alternating
contractions of the muscle layers
(peristalsis)
Esophagus
Slide
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
 Runs from pharynx to stomach through
the diaphragm
 Conducts food by peristalsis
(slow rhythmic squeezing)
 Passageway for food only (respiratory
system branches off after the pharynx)
Layers of Alimentary Canal Organs
Slide
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
 Mucosa
Innermost layer
Moist membrane
Surface epithelium
Small amount of connective tissue
(lamina propria)
Small smooth muscle layer
Layers of Alimentary Canal Organs
Slide
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
 Submucosa
Just beneath the mucosa
Soft connective tissue with blood vessels,
nerve endings, and lymphatics
Layers of Alimentary Canal Organs
Slide
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
 Muscularis externa – smooth muscle
Inner circular layer
Outer longitudinal layer
 Serosa
Outermost layer – visceral peritoneum
Layer of serous fluid-producing cells
Layers of Alimentary Canal Organs
Slide
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
Figure 14.3
Stomach Anatomy
Slide
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
 Located on the left side of the
abdominal cavity
 Food enters at the cardioesophageal
sphincter
Stomach Anatomy
Slide
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
 Regions of the stomach
Cardiac region – near the heart
Fundus
Body
Phylorus – funnel-shaped terminal end
 Food empties into the small intestine at
the pyloric sphincter
Stomach Anatomy
Slide
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
 Rugae – internal folds of the mucosa
 External regions
Lesser curvature
Greater curvature
Stomach Anatomy
Slide
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
 Layers of peritoneum attached to the
stomach
Lesser omentum – attaches the liver to the
lesser curvature
Greater omentum – attaches the greater
curvature to the posterior body wall
Contains fat to insulate, cushion, and
protect abdominal organs
Stomach Anatomy
Slide
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
Figure 14.4a
Stomach Functions
Slide
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
 Acts as a storage tank for food
 Site of food breakdown
 Chemical breakdown of protein begins
 Delivers chyme (processed food) to the
small intestine
Specialized Mucosa of the
Stomach
Slide
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
 Simple columnar epithelium
Mucous neck cells – produce a sticky
alkaline mucus
Gastric glands – secrete gastric juice
Chief cells – produce protein-digesting
enzymes (pepsinogens)
Parietal cells – produce hydrochloric acid
Endocrine cells – produce gastrin
Structure of the Stomach Mucosa
Slide
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
 Gastric pits formed by folded mucosa
 Glands and specialized cells are in the
gastric gland region
Structure of the Stomach Mucosa
Slide
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
Figure 14.4b, c
Small Intestine
Slide
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
 The body’s major digestive organ
 Site of nutrient absorption into the blood
 Muscular tube extending form the
pyloric sphincter to the ileocecal valve
 Suspended from the posterior
abdominal wall by the mesentery
Subdivisions of the Small Intestine
“Dogs Just Itch!
Slide
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
 Duodenum
Attached to the stomach
Curves around the head of the pancreas
 Jejunum
Attaches anteriorly to the duodenum
 Ileum
Extends from jejunum to large intestine
Chemical Digestion in the Small
Intestine
Slide
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
 Source of enzymes that are mixed with
chyme
Intestinal cells
Pancreas
 Bile enters from the gall bladder
Chemical Digestion in the Small
Intestine
Slide
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
Figure 14.6
Villi of the Small Intestine
Slide
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
 Fingerlike
structures formed
by the mucosa
 Give the small
intestine more
surface area
Figure 14.7a
Microvilli of the Small Intestine
Slide
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
 Small projections of the
plasma membrane
 Found on absorptive cells
Figure 14.7c
Structures Involved in Absorption of
Nutrients
Slide
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
 Absorptive cells
 Blood capillaries
 Lacteals (specialized
lymphatic capillaries)
Figure 14.7b
Folds of the Small Intestine
Slide
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
 Called circular folds or plicae circulares
 Deep folds of the mucosa and
submucosa
 Do not disappear when filled with food
 The submucosa has Peyer’s patches
(collections of lymphatic tissue)
Digestion in the Small Intestine
Slide
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
 Enzymes from the brush border
Break double sugars into simple sugars
Complete some protein digestion
 Pancreatic enzymes play the major
digestive function
Help complete digestion of starch
(pancreatic amylase)
Carry out about half of all protein digestion
(trypsin, etc.)
Digestion in the Small Intestine
Slide
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
 Pancreatic enzymes play the major
digestive function (continued)
Responsible for fat digestion (lipase)
Digest nucleic acids (nucleases)
Alkaline content neutralizes acidic chyme
Absorption in the Small Intestine
Slide
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
 Water is absorbed along the length of
the small intestine
 End products of digestion
Most substances are absorbed by active
transport through cell membranes
Lipids are absorbed by diffusion
 Substances are transported to the liver
by the hepatic portal vein or lymph
Propulsion in the Small Intestine
Slide
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
 Peristalsis is the major means of
moving food
 Segmental movements
Mix chyme with digestive juices
Aid in propelling food
Large Intestine
Slide
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
 Larger in diameter, but shorter than the
small intestine
 Frames the internal abdomen
Large Intestine
Slide
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
Figure 14.8
Functions of the Large Intestine
Slide
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
 Absorption of water
 Eliminates indigestible food from the
body as feces
 Does not participate in digestion of food
 Goblet cells produce mucus to act as a
lubricant
Structures of the Large Intestine
Slide
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
 Cecum – saclike first part of the large
intestine
 Appendix
Accumulation of lymphatic tissue that
sometimes becomes inflamed
(appendicitis)
Hangs from the cecum
Structures of the Large Intestine
Slide
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
 Colon
Ascending
Transverse
Descending
S-shaped sigmoidal
 Rectum
 Anus – external body opening
Structures of the Large Intestine
Slide
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
 Colon
Ascending
Transverse
Descending
S-shaped sigmoidal
 Rectum
 Anus – external body opening
Food Breakdown and Absorption in
the Large Intestine
Slide
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
 No digestive enzymes are produced
 Resident bacteria digest remaining
nutrients
Produce some vitamin K and B
Release gases
 Water and vitamins K and B are absorbed
 Remaining materials are eliminated via
feces
Propulsion in the Large Intestine
Slide
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
 Sluggish peristalsis
 Mass movements
Slow, powerful movements
Occur three to four times per day
 Presence of feces in the rectum causes
a defecation reflex
Internal anal sphincter is relaxed
Defecation occurs with relaxation of the
voluntary (external) anal sphincter
Accessory Digestive Organs
Slide
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
 Salivary glands
 Teeth
 Pancreas
 Liver
 Gall bladder
Salivary Glands
Slide
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
 Saliva-producing glands
Parotid glands – located anterior to ears
Submandibular glands
Sublingual glands
Saliva
Slide
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
 Mixture of mucus and serous fluids
 Helps to form a food bolus
 Contains salivary amylase to begin
starch digestion
 Dissolves chemicals so they can be
tasted
Teeth
Slide
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
 The role is to masticate (chew) food
 Humans have two sets of teeth
Deciduous (baby or milk) teeth
20 teeth are fully formed by age two
Teeth
Slide
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
 Permanent teeth
Replace deciduous teeth beginning
between the ages of 6 to 12
A full set is 32 teeth, but some people do
not have wisdom teeth
Classification of Teeth
Slide
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
 Incisors
 Canines
 Premolars
 Molars
Classification of Teeth
Slide
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
Figure 14.9
Regions of a Tooth
Slide
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
 Crown – exposed
part
 Outer enamel
 Dentin
 Pulp cavity
 Neck
 Region in contact
with the gum
 Connects crown to
root
Figure 14.10
Regions of a Tooth
Slide
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
 Root
Periodontal
membrane
attached to the
bone
Root canal carrying
blood vessels and
nerves
Figure 14.10
Pancreas
Slide
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
 Produces a wide spectrum of digestive
enzymes that break down all categories of food
 Enzymes are secreted into the duodenum
 Alkaline fluid introduced with enzymes
neutralizes acidic chyme
 Endocrine products of pancreas
Insulin
Glucagons
Liver
Slide
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
 Largest gland in the body
 Located on the right side of the body
under the diaphragm
 Consists of four lobes suspended from
the diaphragm and abdominal wall by
the falciform ligament
 Connected to the gall bladder via the
common hepatic duct
Bile
Slide
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
 Produced by cells in the liver
 Composition
Bile salts
Bile pigment (mostly bilirubin from the
breakdown of hemoglobin)
Cholesterol
Phospholipids
Electrolytes
Role of the Liver in Metabolism
Slide
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
 Several roles in digestion
 Detoxifies drugs and alcohol
 Degrades hormones
 Produce cholesterol, blood proteins
(albumin and clotting proteins)
 Plays a central role in metabolism
Gall Bladder
Slide
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
 Sac found in hollow fossa of liver
 Stores bile from the liver by way of the
cystic duct
 Bile is introduced into the duodenum in
the presence of fatty food
 Gallstones can cause blockages
Processes of the Digestive System
Slide
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
 Ingestion – getting food into the mouth
 Propulsion – moving foods from one
region of the digestive system to
another
Processes of the Digestive System
Slide
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
Peristalsis – alternating
waves of contraction
Segmentation – moving
materials back and forth
to aid in mixing
Figure 14.12
Processes of the Digestive System
Slide
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
 Mechanical digestion
Mixing of food in the mouth by the tongue
Churning of food in the stomach
Segmentation in the small intestine
Processes of the Digestive System
Slide
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
 Chemical Digestion
Enzymes break down food molecules into
their building blocks
Each major food group uses different
enzymes
Carbohydrates are broken to simple sugars
Proteins are broken to amino acids
Fats are broken to fatty acids and alcohols
Processes of the Digestive System
Slide
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
 Absorption
End products of digestion are absorbed in
the blood or lymph
Food must enter mucosal cells and then
into blood or lymph capillaries
 Defecation
Elimination of indigestible substances as
feces
Processes of the Digestive System
Slide
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
Figure 14.11
Control of Digestive Activity
Slide
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
 Mostly controlled by reflexes via the
parasympathetic division
 Chemical and mechanical receptors are
located in organ walls that trigger
reflexes
Control of Digestive Activity
Slide
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
 Stimuli include:
Stretch of the organ
pH of the contents
Presence of breakdown products
 Reflexes include:
Activation or inhibition of glandular
secretions
Smooth muscle activity
Nutrition - Take a Class!
Slide
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
 Nutrient – substance used by the
body for growth, maintenance, and
repair
 Categories of nutrients
Carbohydrates: simple sugars, starches,
fiber
Lipids: triglycerides, phospholipids, fatty
acids
Proteins: amino acids
Vitamins
Body Energy Balance
Slide
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
 Energy intake = total energy output
(heat + work + energy storage)
Energy intake is liberated during food
oxidation
Energy output
Heat is usually about 60%
Storage energy is in the form of fat or
glycogen

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digestion system detail .ppt

  • 1. Essentials of Human Anatomy & Physiology Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Seventh Edition Elaine N. Marieb Chapter 14 The Digestive System and Body Metabolism
  • 2. The Digestive System and Body Metabolism Slide 14.1 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Digestion Breakdown of ingested food  Absorption Passage of nutrients into the blood  Metabolism Production of cellular energy (ATP)
  • 3. Organs of the Digestive System Slide Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Two main groups  Alimentary canal – continuous coiled hollow tube  Accessory digestive organs
  • 4. Organs of the Digestive System Slide Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Figure 14.1
  • 5. Organs of the Alimentary Canal Slide 14.3 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Mouth  Pharynx  Esophagus  Stomach  Small intestine  Large intestine  Anus
  • 6. Mouth (Oral Cavity) Anatomy Slide 14.4 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Lips (labia) – protect the anterior opening  Cheeks – form the lateral walls  Hard palate – forms the anterior roof  Soft palate – forms the posterior roof  Uvula – fleshy projection of the soft palate Figure 14.2a
  • 7. Mouth (Oral Cavity) Anatomy Slide 14.5 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Vestibule – space between lips externally and teeth and gums internally  Oral cavity – area contained by the teeth  Tongue – attached at hyoid and styloid processes of the skull, and by the lingual frenulum Figure 14.2a
  • 8. Mouth (Oral Cavity) Anatomy Slide 14.6 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Tonsils Palatine tonsils Lingual tonsil Figure 14.2a
  • 9. Processes of the Mouth Slide 14.7 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Mastication (chewing) of food  Mixing masticated food with saliva  Initiation of swallowing by the tongue  Allowing for the sense of taste
  • 10. Pharynx Anatomy Slide 14.8 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Nasopharynx – not part of the digestive system  Oropharynx – posterior to oral cavity  Laryngopharynx – below the oropharynx and connected to the esophagus Figure 14.2a
  • 11. Pharynx Function Slide 14.9 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Serves as a passageway for air and food  Food is propelled to the esophagus by two muscle layers Longitudinal inner layer Circular outer layer  Food movement is by alternating contractions of the muscle layers (peristalsis)
  • 12. Esophagus Slide Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Runs from pharynx to stomach through the diaphragm  Conducts food by peristalsis (slow rhythmic squeezing)  Passageway for food only (respiratory system branches off after the pharynx)
  • 13. Layers of Alimentary Canal Organs Slide Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Mucosa Innermost layer Moist membrane Surface epithelium Small amount of connective tissue (lamina propria) Small smooth muscle layer
  • 14. Layers of Alimentary Canal Organs Slide Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Submucosa Just beneath the mucosa Soft connective tissue with blood vessels, nerve endings, and lymphatics
  • 15. Layers of Alimentary Canal Organs Slide Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Muscularis externa – smooth muscle Inner circular layer Outer longitudinal layer  Serosa Outermost layer – visceral peritoneum Layer of serous fluid-producing cells
  • 16. Layers of Alimentary Canal Organs Slide Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Figure 14.3
  • 17. Stomach Anatomy Slide Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Located on the left side of the abdominal cavity  Food enters at the cardioesophageal sphincter
  • 18. Stomach Anatomy Slide Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Regions of the stomach Cardiac region – near the heart Fundus Body Phylorus – funnel-shaped terminal end  Food empties into the small intestine at the pyloric sphincter
  • 19. Stomach Anatomy Slide Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Rugae – internal folds of the mucosa  External regions Lesser curvature Greater curvature
  • 20. Stomach Anatomy Slide Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Layers of peritoneum attached to the stomach Lesser omentum – attaches the liver to the lesser curvature Greater omentum – attaches the greater curvature to the posterior body wall Contains fat to insulate, cushion, and protect abdominal organs
  • 21. Stomach Anatomy Slide Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Figure 14.4a
  • 22. Stomach Functions Slide Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Acts as a storage tank for food  Site of food breakdown  Chemical breakdown of protein begins  Delivers chyme (processed food) to the small intestine
  • 23. Specialized Mucosa of the Stomach Slide Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Simple columnar epithelium Mucous neck cells – produce a sticky alkaline mucus Gastric glands – secrete gastric juice Chief cells – produce protein-digesting enzymes (pepsinogens) Parietal cells – produce hydrochloric acid Endocrine cells – produce gastrin
  • 24. Structure of the Stomach Mucosa Slide Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Gastric pits formed by folded mucosa  Glands and specialized cells are in the gastric gland region
  • 25. Structure of the Stomach Mucosa Slide Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Figure 14.4b, c
  • 26. Small Intestine Slide Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  The body’s major digestive organ  Site of nutrient absorption into the blood  Muscular tube extending form the pyloric sphincter to the ileocecal valve  Suspended from the posterior abdominal wall by the mesentery
  • 27. Subdivisions of the Small Intestine “Dogs Just Itch! Slide Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Duodenum Attached to the stomach Curves around the head of the pancreas  Jejunum Attaches anteriorly to the duodenum  Ileum Extends from jejunum to large intestine
  • 28. Chemical Digestion in the Small Intestine Slide Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Source of enzymes that are mixed with chyme Intestinal cells Pancreas  Bile enters from the gall bladder
  • 29. Chemical Digestion in the Small Intestine Slide Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Figure 14.6
  • 30. Villi of the Small Intestine Slide Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Fingerlike structures formed by the mucosa  Give the small intestine more surface area Figure 14.7a
  • 31. Microvilli of the Small Intestine Slide Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Small projections of the plasma membrane  Found on absorptive cells Figure 14.7c
  • 32. Structures Involved in Absorption of Nutrients Slide Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Absorptive cells  Blood capillaries  Lacteals (specialized lymphatic capillaries) Figure 14.7b
  • 33. Folds of the Small Intestine Slide Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Called circular folds or plicae circulares  Deep folds of the mucosa and submucosa  Do not disappear when filled with food  The submucosa has Peyer’s patches (collections of lymphatic tissue)
  • 34. Digestion in the Small Intestine Slide Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Enzymes from the brush border Break double sugars into simple sugars Complete some protein digestion  Pancreatic enzymes play the major digestive function Help complete digestion of starch (pancreatic amylase) Carry out about half of all protein digestion (trypsin, etc.)
  • 35. Digestion in the Small Intestine Slide Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Pancreatic enzymes play the major digestive function (continued) Responsible for fat digestion (lipase) Digest nucleic acids (nucleases) Alkaline content neutralizes acidic chyme
  • 36. Absorption in the Small Intestine Slide Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Water is absorbed along the length of the small intestine  End products of digestion Most substances are absorbed by active transport through cell membranes Lipids are absorbed by diffusion  Substances are transported to the liver by the hepatic portal vein or lymph
  • 37. Propulsion in the Small Intestine Slide Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Peristalsis is the major means of moving food  Segmental movements Mix chyme with digestive juices Aid in propelling food
  • 38. Large Intestine Slide Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Larger in diameter, but shorter than the small intestine  Frames the internal abdomen
  • 39. Large Intestine Slide Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Figure 14.8
  • 40. Functions of the Large Intestine Slide Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Absorption of water  Eliminates indigestible food from the body as feces  Does not participate in digestion of food  Goblet cells produce mucus to act as a lubricant
  • 41. Structures of the Large Intestine Slide Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Cecum – saclike first part of the large intestine  Appendix Accumulation of lymphatic tissue that sometimes becomes inflamed (appendicitis) Hangs from the cecum
  • 42. Structures of the Large Intestine Slide Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Colon Ascending Transverse Descending S-shaped sigmoidal  Rectum  Anus – external body opening
  • 43. Structures of the Large Intestine Slide Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Colon Ascending Transverse Descending S-shaped sigmoidal  Rectum  Anus – external body opening
  • 44. Food Breakdown and Absorption in the Large Intestine Slide Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  No digestive enzymes are produced  Resident bacteria digest remaining nutrients Produce some vitamin K and B Release gases  Water and vitamins K and B are absorbed  Remaining materials are eliminated via feces
  • 45. Propulsion in the Large Intestine Slide Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Sluggish peristalsis  Mass movements Slow, powerful movements Occur three to four times per day  Presence of feces in the rectum causes a defecation reflex Internal anal sphincter is relaxed Defecation occurs with relaxation of the voluntary (external) anal sphincter
  • 46. Accessory Digestive Organs Slide Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Salivary glands  Teeth  Pancreas  Liver  Gall bladder
  • 47. Salivary Glands Slide Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Saliva-producing glands Parotid glands – located anterior to ears Submandibular glands Sublingual glands
  • 48. Saliva Slide Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Mixture of mucus and serous fluids  Helps to form a food bolus  Contains salivary amylase to begin starch digestion  Dissolves chemicals so they can be tasted
  • 49. Teeth Slide Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  The role is to masticate (chew) food  Humans have two sets of teeth Deciduous (baby or milk) teeth 20 teeth are fully formed by age two
  • 50. Teeth Slide Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Permanent teeth Replace deciduous teeth beginning between the ages of 6 to 12 A full set is 32 teeth, but some people do not have wisdom teeth
  • 51. Classification of Teeth Slide Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Incisors  Canines  Premolars  Molars
  • 52. Classification of Teeth Slide Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Figure 14.9
  • 53. Regions of a Tooth Slide Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Crown – exposed part  Outer enamel  Dentin  Pulp cavity  Neck  Region in contact with the gum  Connects crown to root Figure 14.10
  • 54. Regions of a Tooth Slide Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Root Periodontal membrane attached to the bone Root canal carrying blood vessels and nerves Figure 14.10
  • 55. Pancreas Slide Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Produces a wide spectrum of digestive enzymes that break down all categories of food  Enzymes are secreted into the duodenum  Alkaline fluid introduced with enzymes neutralizes acidic chyme  Endocrine products of pancreas Insulin Glucagons
  • 56. Liver Slide Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Largest gland in the body  Located on the right side of the body under the diaphragm  Consists of four lobes suspended from the diaphragm and abdominal wall by the falciform ligament  Connected to the gall bladder via the common hepatic duct
  • 57. Bile Slide Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Produced by cells in the liver  Composition Bile salts Bile pigment (mostly bilirubin from the breakdown of hemoglobin) Cholesterol Phospholipids Electrolytes
  • 58. Role of the Liver in Metabolism Slide Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Several roles in digestion  Detoxifies drugs and alcohol  Degrades hormones  Produce cholesterol, blood proteins (albumin and clotting proteins)  Plays a central role in metabolism
  • 59. Gall Bladder Slide Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Sac found in hollow fossa of liver  Stores bile from the liver by way of the cystic duct  Bile is introduced into the duodenum in the presence of fatty food  Gallstones can cause blockages
  • 60. Processes of the Digestive System Slide Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Ingestion – getting food into the mouth  Propulsion – moving foods from one region of the digestive system to another
  • 61. Processes of the Digestive System Slide Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Peristalsis – alternating waves of contraction Segmentation – moving materials back and forth to aid in mixing Figure 14.12
  • 62. Processes of the Digestive System Slide Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Mechanical digestion Mixing of food in the mouth by the tongue Churning of food in the stomach Segmentation in the small intestine
  • 63. Processes of the Digestive System Slide Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Chemical Digestion Enzymes break down food molecules into their building blocks Each major food group uses different enzymes Carbohydrates are broken to simple sugars Proteins are broken to amino acids Fats are broken to fatty acids and alcohols
  • 64. Processes of the Digestive System Slide Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Absorption End products of digestion are absorbed in the blood or lymph Food must enter mucosal cells and then into blood or lymph capillaries  Defecation Elimination of indigestible substances as feces
  • 65. Processes of the Digestive System Slide Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings Figure 14.11
  • 66. Control of Digestive Activity Slide Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Mostly controlled by reflexes via the parasympathetic division  Chemical and mechanical receptors are located in organ walls that trigger reflexes
  • 67. Control of Digestive Activity Slide Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Stimuli include: Stretch of the organ pH of the contents Presence of breakdown products  Reflexes include: Activation or inhibition of glandular secretions Smooth muscle activity
  • 68. Nutrition - Take a Class! Slide Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Nutrient – substance used by the body for growth, maintenance, and repair  Categories of nutrients Carbohydrates: simple sugars, starches, fiber Lipids: triglycerides, phospholipids, fatty acids Proteins: amino acids Vitamins
  • 69. Body Energy Balance Slide Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings  Energy intake = total energy output (heat + work + energy storage) Energy intake is liberated during food oxidation Energy output Heat is usually about 60% Storage energy is in the form of fat or glycogen