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a) What problems can result from each of these types of chromosome rearrangements? (SHOW
WORK & EXPLAIN)
b) Give examples of human aneuploidies including which chromosome has an extra copy, the
name of the resulting syndrome, symptoms, incidence and life expectancy. (SHOW WORK &
EXPLAIN)
c) Define continuous characteristic, polygenic characteristic, pleiotropy and multifactorial
characteristic.
Solution
a.
2.
Trisomy 21 - extra chromosome in the 21st chromosome causing downs syndrome.
Trisomy 18- extra chromosome in 18 th chromosome. Known as Edwards syndrome.
Trisomy 13 - Patau syndrome
Turners syndrome.
Klinefelters syndrome.

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