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Describe 5 key traits the lung cancer cells within the primary tumor acquire and why they are
significant.
•As genetic stability is lost and genetic mutations accumulate some of these mutation result in
advantageous changes to cellular function. As a result, lung cancer cells acquire traits effective
for growth and development of tumors and invasion into surrounding tissue. Describe five of the
traits lung cancer cells have that are advantageous and justify why you chose those traits.
Solution
Thanks for the question
1. self-sufficiency in growth signals- the cell can keep growing by itself
2. insensitivity to growth-inhibitory (antigrowth) signals - the cell looses the ability to restrict its
unrestricted growth
3. evasion of programmed cell death (apoptosis),- the cell looses the ability of the body to evade
death and discard.
4. limitless replicative potential - the cell can keep on multiplying as much as it can without any
blocks or barriers
5. sustained angiogenesis- there is a constant and adequate emergence of blood supply for the
new grown tissues and cells
6. tissue invasion and metastasis. - the cancer cells are able to spread themselves into other
tissues physically and through blood
Each of these physiologic changes cause the successful transformation of non cancer cells to
cancer cells and make ineffective the anticancer defense mechanism present in the cells. These
six capabilities are shared in common by most and perhaps all types of human tumors.
Regards

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Describe 5 key traits the lung cancer cells within the primary tumor.pdf

  • 1. Describe 5 key traits the lung cancer cells within the primary tumor acquire and why they are significant. •As genetic stability is lost and genetic mutations accumulate some of these mutation result in advantageous changes to cellular function. As a result, lung cancer cells acquire traits effective for growth and development of tumors and invasion into surrounding tissue. Describe five of the traits lung cancer cells have that are advantageous and justify why you chose those traits. Solution Thanks for the question 1. self-sufficiency in growth signals- the cell can keep growing by itself 2. insensitivity to growth-inhibitory (antigrowth) signals - the cell looses the ability to restrict its unrestricted growth 3. evasion of programmed cell death (apoptosis),- the cell looses the ability of the body to evade death and discard. 4. limitless replicative potential - the cell can keep on multiplying as much as it can without any blocks or barriers 5. sustained angiogenesis- there is a constant and adequate emergence of blood supply for the new grown tissues and cells 6. tissue invasion and metastasis. - the cancer cells are able to spread themselves into other tissues physically and through blood Each of these physiologic changes cause the successful transformation of non cancer cells to cancer cells and make ineffective the anticancer defense mechanism present in the cells. These six capabilities are shared in common by most and perhaps all types of human tumors. Regards