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ORIGINAL ARTICLE 
Mothers with Depression, Anxiety or Eating Disorders: Outcomes 
on Their Children and the Role of Paternal Psychological Profiles 
Silvia Cimino • Luca Cerniglia • Marinella Paciello 
! Springer Science+Business Media New York 2014 
Abstract The present paper aims to longitudinally assess 
the emotional functioning of children of mothers with 
depression, anxiety, or eating disorders and of mothers with 
no psychological disorders and to evaluate the possible 
mediating role of fathers’ psychological profiles on chil-dren’s 
internalizing/externalizing functioning using SCID 
I, SCL-90/R and CBCL/1!-5. The results showed maternal 
psychopathology to be strongly related to children’s mal-adaptive 
profiles. Children of mothers with depression and 
anxiety showed higher internalizing scores than children of 
other groups. These scores increased from T1 to T2. 
Children of mothers with eating disorders showed higher 
and increasing externalizing scores than children of other 
groups. The data showed that fathers’ interpersonal sensi-tivity, 
depression, anxiety and psychoticism significantly 
predicted internalizing problems of the children. Moreover, 
interpersonal sensitivity and psychoticism significantly 
predicted externalizing problems. Our results confirmed the 
impact of maternal psychopathology on maladaptive out-comes 
in their children, which suggests the importance of 
considering paternal psychological profiles. 
Keywords Infancy ! Maladaptive functioning ! Paternal 
psychological profile 
Introduction 
The international scientific literature points to parental 
psychopathology as a crucial risk factor for the develop-ment 
and maintenance of emotional and behavioral prob-lems 
in children in the first years of life [1]. Douglas [2] 
states that the more severe mothers’ and fathers’ mental 
issues are, the faster the child will develop behavioral 
problems. Additionally, Riahi Amini and Salehi Veisi [3] 
found a positive correlation between maternal symptoms 
and children’s behavioral problems. An intensification in 
maternal symptoms increases their children’s behavioral 
problems, especially when their fathers’ psychological 
profiles are at risk and the paternal involvement in child 
rearing is scarce. In particular, many studies have focused 
on the influence of maternal depression on internalizing 
problems in children, on the impact of maternal eating 
disorders (EDs) on children’s mental health [4, 5], and 
have considered the possible role of paternal psychopa-thology 
as a mediating variable [6]. 
Some studies have found that mothers afflicted by major 
depression or panic disorder most likely have children who 
suffer from emotional behavioral problems. Moreover, 
maternal depression is associated with depressive disorder, 
social phobia, disruptive behavior, separation anxiety, 
multiple anxiety disorder and compromised social function 
in children; maternal panic disorder is associated with 
panic disorder, acrophobia, separation anxiety and multiple 
anxiety disorder in children [7, 8]. It is suggested that these 
results are mediated by protective or risk factors related to 
paternal psychological functioning and/or the quality of 
father–infant attachment [9]. 
Murray et al. [10] demonstrated that maternal depres-sion 
in the early postpartum months was the best predictor 
of child behavioral problems, which were not influenced by 
S. Cimino 
Department of Dynamic and Clinical Psychology, ‘‘Sapienza’’ 
University of Rome, Rome, Italy 
e-mail: silvia.cimino@uniroma1.it 
L. Cerniglia (&) ! M. Paciello 
Department of Psychology, International Telematic University 
Uninettuno of Rome, Rome, Italy 
e-mail: l.cerniglia@uninettunouniversity.net 
M. Paciello 
e-mail: m.paciello@uninettunouniversity.net 
123 
Child Psychiatry Hum Dev 
DOI 10.1007/s10578-014-0462-6
current maternal depression but mediated by fathers’ 
involvement. Moreover, Luoma et al. [11] conducted a 
longitudinal analysis in Finland, and the results showed 
that prenatal maternal depression was associated with 
higher levels of child behavioral problems and that prenatal 
and recurrent maternal depressive symptoms led to the 
most negative child outcomes in absence of protective 
factors provided by the fathers. By the preschool years, 
children exposed to chronic maternal depression had higher 
levels of parent-reported internalizing and externalizing 
behavioral problems. 
A meta-analysis demonstrated that the relationship 
between maternal depression and conduct problems 
extends to adolescence. In addition, maternal depression 
has been shown to mediate the relationship between 
exposure to community violence and adolescent behavioral 
problems, which highlights its powerful effect on long-term 
child outcomes [12–17]. 
Regarding studies of maternal eating disorders, an 
increased incidence of early feeding disorders has been 
shown in children whose mothers were more intrusive and 
controlling in the feeding context and had difficulties rec-ognizing 
the child’s signals of hunger and satiety and 
regulation of the affective states of the child [18–23]. 
These results proved to be particularly severe in the pre-sence 
of psychopathological symptoms in the partners of 
women with EDs because they appear to facilitate the onset 
of emotional disorders in their children [24]. 
Indeed, Maldonado-Dura`n [25] found that caregivers 
(both mothers and fathers) had more difficulties in 
expressing positive affect in families with children with 
feeding disorders. These caregivers showed more negative 
affect and a lower ability to read the communication sig-nals 
of the child. Furthermore, the children revealed 
problematic characteristics in their feeding patterns, diffi-culty 
regulating their state during meals, temperamental 
difficulties, and behavioral problems such as opposition, 
negativity, and stubbornness. 
Although some researchers have found that children of 
depressed or anxious parents are themselves at a substan-tially 
increased risk (twofold to fivefold) of psychiatric 
disorders [26–29], there are currently few studies that focus 
on maternal anxiety disorder (not otherwise specified). 
Moreover, there are few longitudinal studies that examine 
the emotional-adaptive development of children with 
mothers and/or fathers with psychopathological difficulties. 
As shown above, the research that has examined pater-nal 
psychopathology has suggested that it may play a 
crucial role in the quality of caregiving by modulating and 
integrating with interactional mother–infant patterns. In 
particular, Elgar, Mills and McGrath [30] note that a father 
with psychopathologic symptoms who shows a low level of 
responsiveness to his children may be a risk factor for the 
Child Psychiatry Hum Dev 
onset of children’s maladaptive behavior. Indeed, Pinquart 
and Teubert [31] state that a combination of maternal and 
paternal psychopathologies may create a style of co-par-enting 
dominated by negative interactive cycles with the 
children. On the other hand, adaptive paternal psycholog-ical 
functioning may be a protective factor against the 
development of psychopathologies in children by facili-tating 
mothers’ understanding of their children’s needs 
[32]. However, although the role of fathers have been 
increasingly considered in recent years, it seems useful to 
deepen the study of paternal psychopathological risk as a 
possible mediating variable in the onset of impaired 
adjustment in children, especially in the presence of spe-cific 
maternal psychological difficulties [33]. 
Based on these theoretical premises, a longitudinal study 
is proposed here to assess the impact of specific maternal 
psychopathology on specific frameworks of child func-tioning 
that deepens the role of paternal psychopathologi-cal 
risk over time. 
In particular, the present prospective study has set the 
following specific objective: 
• to assess the adaptive emotional functioning (internal-izing, 
externalizing) of children of mothers with 
depression, anxiety, and eating disorders and of moth-ers 
with no psychological disorder considering the 
possible impact of the fathers’ psychological profiles 
over time on children’s internalizing/externalizing 
functioning. 
Methods 
Sample 
To recruit the sample for our study, we planned two sub-sequent 
sessions of assessment. In a period of 1 year (T1), 
N = 251 families were recruited through nurseries, pri-mary 
schools (N = 146) and mental health clinics 
(N = 105) in Central Italy. Families with children in the 
first 3 years of life were contacted by a group of trained 
psychologists who described the purposes and methods of 
the study, gave explanations about the questionnaires to be 
administered and gathered an informant consent from all 
the participants. Thanks to the collaboration of teachers 
and mental health workers, all the parents in schools and 
clinics were informed of the possibility of participating in 
the research. We administered all the sections of the SCID I 
(Non-Patient Edition) [34] to the mothers. The SCID II, 
which assesses personality disorders, was not administered. 
Our sample is divided into four subgroups: (a) three clin-ical 
subgroups were composed by families in which the 
mothers suffered from Anxiety Disorder (N = 42), 
123
Depression Disorder (N = 39) or Eating Disorder 
(N = 44) without a comorbidity disorder and (b) families 
in which the mothers received no diagnosis (N = 126). We 
chose not to include mothers who were pursuing treatment 
to avoid the bias of the effect of a psychotherapeutic 
intervention over time on the families’ dynamics (N = 9). 
Consistent with several perspective studies [35], the 
drop-off rate in the sample at the second time point (T2, 
3 years after) was *45 % of the original number of sub-jects. 
We excluded the families with missing data in their 
administered questionnaires (N = 54). Thus, at T2 we 
assessed N = 80 families. The four groups have been then 
paired by age of the children, age of the mothers and the 
families’ socio-economic status. 
The sample presented for the present study is composed 
of N = 80 families with firstborn children with a mean age 
of T1 = 2.3 years (SD = 1.1) and T2 = 5.1 (SD = .08). 
Most of the parents (87 %) were of middle socio-eco-nomic 
status (SES) [36]. Sixty-eight percent of the parents 
lived together; 88 % of the fathers and 71 % of the mothers 
worked; 83 % of the children went to nursery or kinder-garten; 
88 % of the children have been breast-fed. All the 
partners of the mothers recruited for the present study were 
the biological fathers of the children, and all parents were 
Caucasian. The mean age of the fathers at T1 was 
35.3 years of age (SD = 2.5), and the mean age of the 
mothers at T1 was 33.2 years of age (SD = 3.1). 
Tools and Procedures 
The assessment was administered face-to-face by a group 
of trained psychologists who visited the families at their 
home or at mental health clinics. During these visits, a set 
of self-report and report-form tools were administered, and 
all the parents signed an informed consent for all the 
procedures. 
At the evaluation times (T1 and T2), the parents of both 
the Clinical Groups and the Non Clinical Group were 
administered the following tools: 
SCL-90-R: The Symptom Checklist-90-Revised (SCL- 
90-R) is a 90-item self-report symptom 
inventory aimed to measure psychological 
symptoms and psychological distress [37]. 
The main symptom dimensions are 
Somatization, Obsessive–Compulsive, Inter-personal 
Sensitivity, Depression, Anxiety, 
Hostility, Phobic Anxiety, Paranoid Ideation 
and Psychoticism. The internal coherence 
tested within a sample of adolescent and 
adults is satisfying (alpha between .70 and 
.96), and the clinical cut-off =1 [38] 
CBCL: The Child Behavior Checklist (CBCL) is a 
questionnaire filled out by parents and 
caregivers to assess a child’s abilities 
and his/her specific behavioral/emotional 
characteristics. The CBCL/1!-5 [39] is 
composed of 100 items. The Internalizing 
Problem Scale consists of the Emotionally 
Reactive, Anxious/Depressed, Somatic 
Complaints and Withdrawn Subscales. The 
Externalizing Problem Scale is composed of 
the Attention Problems and Aggressive 
Behavior subscales. The CBCL/1!-5 has a 
high test–retest reliability and a high internal 
consistency [39] (Italian validated version 
and Italian cut-offs, 40). Each parent 
independently completed the questionnaires 
at T1 and T2 
Analyses 
Before performing the analyses, the variables’ normality 
and the congruence between the mothers’ and fathers’ 
evaluations of the child’s internalizing and externalizing 
problems were preliminarily ascertained. All the variables 
were normally distributed, and the correlations among the 
mothers’ and fathers’ evaluations on the children’s CBCL 
dimensions were highly and significantly correlated ([.30). 
Thus, we decided to aggregate the mothers’ and fathers’ 
scores on the CBCL using mean scores. 
We began the analyses by examining the stability and 
change of the children’s internalizing and externalizing 
problems over time for each group of mothers with a 
specific disorder (anxiety, depression and eating disorders) 
and without diagnosis (normative group). Specifically, we 
examined the mean score differences from Time 1 to Time 
2 on the children’s problems by performing repeated 
measure analyses of variance using time as a within-subject 
factor and group as a between subject factor. Moreover, a 
one-way ANOVA was used to test the differences among 
the groups on internalizing and externalizing dimensions 
separately for each time. Then, we examined how the 
fathers’ psychological profiles at T1 were associated with 
the children’s internalizing and externalizing problems by 
performing correlation analyses and standard regressions 
with the fathers’ variables as predictors. Moreover, we 
examined whether and how the fathers’ SCL-90-R sub-scales 
were associated with the mothers’ disorders at Time 
1 by analyzing the point-biserial correlation coefficients. 
Finally, to test the influence of the mothers’ disorders and 
the fathers’ psychological risk on internalizing and exter-nalizing 
children’s problems, four hierarchical regression 
analyses were performed separately for the two assessment 
Child Psychiatry Hum Dev 
123
points (T1 and T2). In all the regression models, the pre-sence/ 
absence of each specific disorder of the mother was 
entered at step 1 and the fathers’ scores on the SCL-90-R 
subscales were entered at step 2. We also evaluated the 
influence of the interaction of the mothers’ and fathers’ 
characteristics on the children’s internalizing and exter-nalizing 
problems by entering the product of each mothers’ 
disorders and each fathers’ SCL-90-R subscale at T1 at 
step 3. These analyses revealed no statistically significant 
interactions. 
Results 
Mothers’ Disorders and Children’s Internalizing 
and Externalizing Problems 
The repeated analyses results indicated that the children’s 
internalizing and externalizing scores were not stable over 
time [F(1,80) = 74,42; p= at p.001 with an eta square 
of .48 and F(1,80) = 9,87; p= at p.01 with an eta square 
of .11, respectively] and that there were significant inter-action 
between time and group [F(1,80) = 12,31; p= at 
p.001 with eta square .32 and F(1,80) = 11,81; p= at 
p.001 with eta square .31, respectively]. More specifi-cally, 
the multiple comparison tests indicated that the 
internalizing problems tended to increase over time for all 
the children. This result was particularly strong in the 
group of mothers with depression, but the children’s 
externalizing problems tended to increase over time only in 
the group of mothers with an eating disorder (Table 1). 
Analyses on the children’s psychological profile showed 
significant differences on both internalizing [Time 1: 
F(3,80) = 26,65; p= at p.001 with an eta square of .50; 
Time 2: F(3,80) = 30; p= at p.001 with an eta square of 
.53] and externalizing problems [Time 1: F(3,80) = 37,43; 
p= at p.001 with an eta square of .58; Time 2: 
F(3,80) = 34,27; p= at p.001 with an eta square of .56]. 
Child Psychiatry Hum Dev 
The significant differences are that (a) the children of 
mothers of the three clinical groups showed higher inter-nalizing 
scores than did those of the normative group that 
(b) the children of mothers with depression and eating 
disorders showed higher externalizing scores than did those 
of the normative group or anxiety group. More specifically, 
at Time 2, the children of mothers with depression showed 
higher internalizing scores than did other children, but the 
children of mothers with an eating disorder showed higher 
externalizing scores than did other children. The normative 
group showed the lowest internalizing and externalizing 
problems at both time points. 
Fathers’ Psychological Profile and Their Child’s 
Problems 
Regarding the possible associations between the fathers’ 
psychopathological risk and their children’s psychological 
problems at both T1 and T2, correlational analyses attested 
that (a) interpersonal sensitivity and depression dimensions 
were significantly and positively associated with both 
internalizing and externalizing problems, that (b) obses-sive– 
compulsive and anxiety dimensions were significantly 
and positively associated with internalizing problems and 
negatively associated with externalizing problems, and that 
(c) psychoticism and hostility dimensions were particularly 
associated with externalizing problems (Table 2). The 
results of the regression analyses also attested to the 
influence of the fathers’ psychological scores on their 
child’s problems, which confirmed some associations. The 
fathers’ interpersonal sensitivity, depression, anxiety and 
psychoticism significantly predicted internalizing problems 
of their child at both Time 1 (45 % of explained variance) 
and Time 2 (48 % of explained variance). Moreover, at T1, 
interpersonal sensitivity and psychoticism significantly 
predicted externalizing problems (51 % of explained vari-ance), 
and hostility and psychoticism significantly pre-dicted 
externalizing problems at Time 2. 
Table 1 Means (SD) of child’s internalizing and externalizing problems by mother’s group at Time 1 and Time 2 
Internalizing problems (clinical cut off[16) Externalizing problems (clinical cut off[21) 
T1 T2 T1–T2 T1 T2 T1–T2 
Anxiety disorder 19.6 (6.2) a 21.2 (5.6) a ** 6.31 (5.7) a 5.71 (3.5) a ns. 
Depression disorder 17.7 (5.5) a 23.1 (6.9) a *** 27.29 (13.0) b 26.54 (14.3) b ns. 
Eating disorder 17.93 (8.0) a 19.1 (8.0) a * 25.57 (12.5) b 30.20 (15.2) b *** 
Normative 5.24 (2.7) b 6.9 (3.1) b ** 2.98 (1.7) a 4.21 (2.1) a ns. 
Total sample 15.12 (8.18) 17.61 (8.8) 15.55 (14.47) 16.62 (15.73) 
The letters indicate significant differences among the group 
T1 Time 1, T2 Time 2, T1–T2 difference from Time 1 to Time 2, Fisher F ANOVA at each time, g2 eta square 
*** p.001; ** p.01; * p.05; ns not significant 
123
Child Psychiatry Hum Dev 
Table 2 Regressions and point-biserial correlations on fathers’ dimensions, child’s problems and mothers’ disorders 
Impact of Mothers’ Disorders and Fathers’ 
Psychological Profiles on Their Children’s Internalizing 
and Externalizing Problems 
The correlation results suggested that there were significant 
associations between the fathers’ dimensions and the 
mothers’ disorders. In particular, the fathers’ interpersonal 
sensitivity and depression were very significantly and 
positively related to the mothers’ depression disorder. The 
fathers’ anxiety and obsessive–compulsive symptoms were 
very significantly and positively related to the mothers’ 
anxiety disorder. Finally, the fathers’ hostility and psych-oticism 
were very significantly and positively related to the 
mothers’ eating disorder (Table 2). 
As shown in Table 3, all the regression models attested 
that the mothers’ disorder significantly predicts their chil-dren’s 
outcomes, concurrently (51 and 60 % of the 
explained variance for internalizing and externalizing 
problems, respectively) and longitudinally (54 and 66 % of 
the explained variance for internalizing and externalizing 
problems, respectively). In particular, the mothers’ eating 
disorders and depression significantly and positively 
influence their children’s externalizing and internalizing 
problems; instead, the mothers’ anxiety significantly and 
positively influences only their child’s internalizing prob-lems. 
Moreover, after controlling the mothers’ disorders, 
the fathers’ psychological profiles significantly predicted 
their children’s outcomes (explaining between 09 and 
12 % of the variance) with the only exception of exter-nalizing 
problems at Time 2. In particular, the fathers’ 
interpersonal sensitivity and anxiety are significantly and 
positively associated with their child’s internalizing prob-lems 
and mediate the influence of the mothers’ depression 
disorder, but the fathers’ obsessive–compulsive dimension 
is significantly and negatively related to their child’s 
externalizing problems at Time 1. 
Discussion 
The present paper aimed to assess the impact of specific 
maternal psychopathology on particular frameworks of 
their children’s functioning by considering the role of 
paternal psychopathological risk over time. 
Our results are in line with the international scientific 
literature that suggests that mothers’ psychopathology can 
foster their children’s emotional and behavioral problems, 
which increase in their severity during development [3]. In 
fact, in our study, the children of mothers with a diagnosis 
showed significantly higher scores on all internalizing and 
externalizing dimensions than did the healthy group chil-dren 
at both Time 1 and Time 2. In particular, the data 
show that specific diagnoses in the mothers are related to 
precise maladaptive emotional and behavioral patterns in 
their children. 
In Figs. 1, 2 and 3, we present a graphical representation 
of our main findings from regression analyses: 
As shown in Fig. 1, we did not find a significant and 
direct effect of maternal depression on their child’s emo-tional/ 
behavioral functioning if considered together with 
the paternal psychopathological risk. Rather, our results 
show that the fathers’ interpersonal sensitivity predicts 
their children’s internalizing problems. This result is con-sistent 
with Lovejoy and colleagues’ work [41] that sug-gested 
that, in specific family configurations, fathers’ 
psychopathological risk could have an even more severe 
Mean 
(SD) 
Internalizing problems Externalizing problems Mother disorder 
T1 T2 T1 T2 Anxiety Depression Eating 
R b r b r b r b r R r 
Somatization (F) .48 (29) .28** Ns .26** Ns .10 Ns .15* Ns -.04 .08 .07 
Obsessive– 
compulsive (F) 
1.0 (1.0) .35*** Ns .27** Ns -.39*** -.37? -.38*** Ns .80*** -.25* -.30* 
Interpersonal 
sensitivity (F) 
.86 (1.0) .24* .35* .40*** .36* .44*** .36* .37*** Ns -.33** .88*** -.32* 
Depression (F) .99 (.98) .28** .31* .44*** .43** .46*** Ns .39*** Ns -.25* .90*** -.32* 
Anxiety (F) .88 (.99) .40*** .57** .32** .56** -.34*** Ns -.33** Ns .79** -.24* -.28* 
Hostility (F) .88 (.94) .22* Ns .13 Ns .45*** Ns .56*** .31* -.36** -.16 .81*** 
Phobic anxiety (F) .32 (.37) .06 Ns .09 Ns .16 Ns .17 Ns -.16 .22* -.07 
Paranoid ideation (F) .53 (.42) .11 Ns .15 Ns .10 Ns .11 Ns -.20 .26* -.09 
Psychoticism (F) .81 (1.0) .22* .38* .13 .39* .41*** .51*** .52*** .51** -.29* -.25* .88*** 
b regression beta coefficients, F fathers’ dimensions at Time 1, T1 Time 1, T2 Time 2 
*** p.001; ** p.01; * p.05; ? p.06 
123
Table 3 Parents’ impact on their child’s internalizing and externalizing problems at Time 1 and Time 2 
Child Psychiatry Hum Dev 
Internalizing problems Externalizing problems 
Time 1 Time 2 Time 1 Time 2 
b1 b2 R Ch. b1 b2 R Ch. b1 b2 RCh. b1 b2 R Ch. 
Step 1 
Anxiety disorder (M) .67*** .49*** .51*** .59*** .45** .54*** Ns .52*** .60*** Ns Ns .66*** 
Depression disorder (M) .76*** Ns. .87*** Ns .75*** .67*** .49*** Ns 
Eating disorder .68*** .66*** .57*** .59*** .73*** .51** .87*** .51*** 
Step 2 
Somatization (F) Ns. .12* Ns. .10* Ns .09* Ns. .06 
Obsessive–compulsive (F) Ns. Ns. -.45*** Ns. 
Interpersonal sensitivity (F) .40** .36* Ns Ns. 
Depression (F) Ns. Ns. Ns Ns. 
Anxiety (F) .37? .38* Ns Ns. 
Hostility (F) Ns. Ns. Ns Ns. 
Phobic anxiety (F) Ns. Ns. .15? Ns. 
Paranoid ideation (F) Ns. Ns. Ns Ns. 
Psychoticism (F) Ns. Ns. Ns Ns. 
R2 .62*** .64*** .69*** .73*** 
AR2 .57 .57 .64 .68 
R Ch R change, b1 beta at step 1, b2 beta at step 2, R2 = R square, AR adjusted R2, Ns not significant, M mother’s disorders at Time 1 
(1 = presence; 0 = absence), F fathers’ psychological dimensions at Time 1 
*** p.001; ** p.01; * p.05;? p.06 
Fig. 1 Conceptual model—mothers with depression Fig. 2 Conceptual model—mothers with anxiety 
impact on their children’s psychological functioning than 
does maternal depression. It is possible that the reciprocally 
influencing relationship we found between the mothers’ 
depression and the fathers’ interpersonal sensitivity might 
express a maladjustment in the couple functioning, which 
in turn could reflect on the fathers’ capacity for quality 
interactions with his son or daughter; poor caregiving has 
been widely recognized to be a predictor of infants’ 
internalizing (and externalizing) problems [42]. 
Figure 2 shows that the mothers’ and fathers’ anxiety 
significantly and directly predicts their children’s 
internalizing problems. It is important to note that psy-chological/ 
psychopathological difficulties of mothers and 
fathers are connected with a bidirectional influence in our 
sample; thus, we can hypothesize in agreement with the 
studies of Weissmann et al. [26] that parents often share a 
specific psychological difficulty whose cumulative weight 
impairs their child’s emotional and behavioral functioning 
in the direction of internalizing problems. 
Figure 3 shows that maternal eating disorders predict 
externalizing problems in children. Paternal psychoticism 
does not predict children’s problems, but it is reciprocally 
123
Child Psychiatry Hum Dev 
connected to maternal disorders. In this case, it is possible 
hypothesize that mothers’ eating disorders have such an 
intense impact on their children’s psychological function-ing 
that the weight of paternal psychopathological risk is 
lost. In line with the studies of Sarkadi and colleagues [43], 
we can suppose that the mother is most likely responsible 
for feeding the child (with fathers less often involved in the 
feeding of young children) and that this specific maternal 
disorder powerfully impacts the child’s emotional and 
behavioral functioning because the mother–infant dyad 
interacts every day in supposedly difficult interactions 
during meals. 
These results highlight the importance of assessing the 
whole family (mother, father and children) over time and 
the significance of an early intervention because our study 
indicates an increase in children’s maladaptive psycho-logical 
profiles from T1 to T2 that could be avoided with 
well-timed clinical work [25]. The interesting bidirectional 
relationship between maternal and paternal psychopatho-logical 
symptoms (as discussed above) must be more 
specifically addressed in a future study because we 
hypothesize that it influences the general functioning of the 
family and particularly the parents’ caregiving quality, 
which in turn is connected to possible maladaptive out-comes 
in their children. This issue is relevant for the 
organization of intervention practices that must involve the 
whole family and assess possible marital maladjustment 
[44] to better understand how various psychopathological 
maternal and paternal symptoms can interact and impact 
the psychological welfare of their children. 
Our study has several strengths. It considered various 
maternal diagnostic groups and their effects on their chil-dren’s 
emotional/behavioral functioning over time, but it 
also measured the possible mediating effect of paternal 
psychopathology. Both parents completed the CBCL, but 
many previous studies included self-report questionnaires 
completed only by the mother. Our study has some limi-tations. 
The study has a homogeneous sample, which 
included only Caucasians of middle socio-economic status 
with mainly two traditional working parents. Moreover, we 
did not administer the SCID-II to assess personality dis-orders 
in the mothers, and we did not evaluate the severity 
of the mothers’ diagnosis with a specific tool. We did not 
administer the SCID I to fathers but relied on the SCL-90- 
R self-report questionnaire, whose scores were not con-firmed 
by other tools and/or clinical interviews adminis-tered 
by trained psychologists. We did not directly observe 
the children’s behavior and characteristics but used a 
widely used and validated report-form questionnaire. We 
also did not address possible differences in the psycho-logical 
functioning of the sons or daughters of mothers 
with eating disorders or of mothers with other diagnoses as 
the international literature suggests [45]. These limitations 
constitute a motivation to continue our research and take 
samples of mothers with comorbidities into consideration. 
Summary 
Several authors suggest that parents’ psychopathology can 
foster the onset of maladaptive psychological profiles in 
their children. It has been demonstrated that children’s 
psychological difficulties tend to increase over time, par-ticularly 
in families in which the mother suffers from 
depression, anxiety or eating disorders. It has also been 
suggested that fathers’ psychopathological risk may be a 
risk factor for the onset of difficulties in their children. The 
present study focused on assessing the emotional func-tioning 
of the children of mothers with various diagnoses 
and of mothers with no psychological disorder while con-sidering 
the possible mediating role of the fathers’ psy-chological 
profiles on their children’s internalizing/ 
externalizing functioning. We used the SCID I [25], SCL- 
90/R [36], and CBCL/1!-5 [39]. The analyses showed that 
the children’s internalizing and externalizing scores tended 
to increase from T1 to T2. Maternal psychopathology 
proved to be strongly related to their children’s maladap-tive 
profiles. Specifically, the children of mothers with 
depression showed higher internalizing scores than did 
children of other groups, and these scores increased from 
T1 to T2; the children of mothers with eating disorders 
showed higher and increasing externalizing scores than did 
other children. The children of mothers with a diagnosis 
showed significantly higher scores in all internalizing and 
externalizing dimensions than did the healthy group chil-dren 
at both Time 1 and Time 2. In particular, the children 
showed specific maladaptive profiles depending on what 
diagnosis their mother received. Mothers with depression 
were more likely to have a withdrawn child, and mothers 
with eating disorders had a higher probability of having 
aggressive children. Furthermore, the fathers’ interpersonal 
Fig. 3 Conceptual model—mothers with eating disorders 
123
sensitivity, depression, anxiety and psychoticism signifi-cantly 
predicted internalizing problems of their children at 
both T1 and T2. Moreover, at T1, the fathers’ interpersonal 
sensitivity and psychoticism significantly predicted their 
child’s externalizing problems, and the fathers’ hostility 
and psychoticism significantly predicted their child’s 
externalizing problems at T2. 
References 
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Mothers with eating disorders, depression and anxietyArticolo diagnosi

  • 1. ORIGINAL ARTICLE Mothers with Depression, Anxiety or Eating Disorders: Outcomes on Their Children and the Role of Paternal Psychological Profiles Silvia Cimino • Luca Cerniglia • Marinella Paciello ! Springer Science+Business Media New York 2014 Abstract The present paper aims to longitudinally assess the emotional functioning of children of mothers with depression, anxiety, or eating disorders and of mothers with no psychological disorders and to evaluate the possible mediating role of fathers’ psychological profiles on chil-dren’s internalizing/externalizing functioning using SCID I, SCL-90/R and CBCL/1!-5. The results showed maternal psychopathology to be strongly related to children’s mal-adaptive profiles. Children of mothers with depression and anxiety showed higher internalizing scores than children of other groups. These scores increased from T1 to T2. Children of mothers with eating disorders showed higher and increasing externalizing scores than children of other groups. The data showed that fathers’ interpersonal sensi-tivity, depression, anxiety and psychoticism significantly predicted internalizing problems of the children. Moreover, interpersonal sensitivity and psychoticism significantly predicted externalizing problems. Our results confirmed the impact of maternal psychopathology on maladaptive out-comes in their children, which suggests the importance of considering paternal psychological profiles. Keywords Infancy ! Maladaptive functioning ! Paternal psychological profile Introduction The international scientific literature points to parental psychopathology as a crucial risk factor for the develop-ment and maintenance of emotional and behavioral prob-lems in children in the first years of life [1]. Douglas [2] states that the more severe mothers’ and fathers’ mental issues are, the faster the child will develop behavioral problems. Additionally, Riahi Amini and Salehi Veisi [3] found a positive correlation between maternal symptoms and children’s behavioral problems. An intensification in maternal symptoms increases their children’s behavioral problems, especially when their fathers’ psychological profiles are at risk and the paternal involvement in child rearing is scarce. In particular, many studies have focused on the influence of maternal depression on internalizing problems in children, on the impact of maternal eating disorders (EDs) on children’s mental health [4, 5], and have considered the possible role of paternal psychopa-thology as a mediating variable [6]. Some studies have found that mothers afflicted by major depression or panic disorder most likely have children who suffer from emotional behavioral problems. Moreover, maternal depression is associated with depressive disorder, social phobia, disruptive behavior, separation anxiety, multiple anxiety disorder and compromised social function in children; maternal panic disorder is associated with panic disorder, acrophobia, separation anxiety and multiple anxiety disorder in children [7, 8]. It is suggested that these results are mediated by protective or risk factors related to paternal psychological functioning and/or the quality of father–infant attachment [9]. Murray et al. [10] demonstrated that maternal depres-sion in the early postpartum months was the best predictor of child behavioral problems, which were not influenced by S. Cimino Department of Dynamic and Clinical Psychology, ‘‘Sapienza’’ University of Rome, Rome, Italy e-mail: silvia.cimino@uniroma1.it L. Cerniglia (&) ! M. Paciello Department of Psychology, International Telematic University Uninettuno of Rome, Rome, Italy e-mail: l.cerniglia@uninettunouniversity.net M. Paciello e-mail: m.paciello@uninettunouniversity.net 123 Child Psychiatry Hum Dev DOI 10.1007/s10578-014-0462-6
  • 2. current maternal depression but mediated by fathers’ involvement. Moreover, Luoma et al. [11] conducted a longitudinal analysis in Finland, and the results showed that prenatal maternal depression was associated with higher levels of child behavioral problems and that prenatal and recurrent maternal depressive symptoms led to the most negative child outcomes in absence of protective factors provided by the fathers. By the preschool years, children exposed to chronic maternal depression had higher levels of parent-reported internalizing and externalizing behavioral problems. A meta-analysis demonstrated that the relationship between maternal depression and conduct problems extends to adolescence. In addition, maternal depression has been shown to mediate the relationship between exposure to community violence and adolescent behavioral problems, which highlights its powerful effect on long-term child outcomes [12–17]. Regarding studies of maternal eating disorders, an increased incidence of early feeding disorders has been shown in children whose mothers were more intrusive and controlling in the feeding context and had difficulties rec-ognizing the child’s signals of hunger and satiety and regulation of the affective states of the child [18–23]. These results proved to be particularly severe in the pre-sence of psychopathological symptoms in the partners of women with EDs because they appear to facilitate the onset of emotional disorders in their children [24]. Indeed, Maldonado-Dura`n [25] found that caregivers (both mothers and fathers) had more difficulties in expressing positive affect in families with children with feeding disorders. These caregivers showed more negative affect and a lower ability to read the communication sig-nals of the child. Furthermore, the children revealed problematic characteristics in their feeding patterns, diffi-culty regulating their state during meals, temperamental difficulties, and behavioral problems such as opposition, negativity, and stubbornness. Although some researchers have found that children of depressed or anxious parents are themselves at a substan-tially increased risk (twofold to fivefold) of psychiatric disorders [26–29], there are currently few studies that focus on maternal anxiety disorder (not otherwise specified). Moreover, there are few longitudinal studies that examine the emotional-adaptive development of children with mothers and/or fathers with psychopathological difficulties. As shown above, the research that has examined pater-nal psychopathology has suggested that it may play a crucial role in the quality of caregiving by modulating and integrating with interactional mother–infant patterns. In particular, Elgar, Mills and McGrath [30] note that a father with psychopathologic symptoms who shows a low level of responsiveness to his children may be a risk factor for the Child Psychiatry Hum Dev onset of children’s maladaptive behavior. Indeed, Pinquart and Teubert [31] state that a combination of maternal and paternal psychopathologies may create a style of co-par-enting dominated by negative interactive cycles with the children. On the other hand, adaptive paternal psycholog-ical functioning may be a protective factor against the development of psychopathologies in children by facili-tating mothers’ understanding of their children’s needs [32]. However, although the role of fathers have been increasingly considered in recent years, it seems useful to deepen the study of paternal psychopathological risk as a possible mediating variable in the onset of impaired adjustment in children, especially in the presence of spe-cific maternal psychological difficulties [33]. Based on these theoretical premises, a longitudinal study is proposed here to assess the impact of specific maternal psychopathology on specific frameworks of child func-tioning that deepens the role of paternal psychopathologi-cal risk over time. In particular, the present prospective study has set the following specific objective: • to assess the adaptive emotional functioning (internal-izing, externalizing) of children of mothers with depression, anxiety, and eating disorders and of moth-ers with no psychological disorder considering the possible impact of the fathers’ psychological profiles over time on children’s internalizing/externalizing functioning. Methods Sample To recruit the sample for our study, we planned two sub-sequent sessions of assessment. In a period of 1 year (T1), N = 251 families were recruited through nurseries, pri-mary schools (N = 146) and mental health clinics (N = 105) in Central Italy. Families with children in the first 3 years of life were contacted by a group of trained psychologists who described the purposes and methods of the study, gave explanations about the questionnaires to be administered and gathered an informant consent from all the participants. Thanks to the collaboration of teachers and mental health workers, all the parents in schools and clinics were informed of the possibility of participating in the research. We administered all the sections of the SCID I (Non-Patient Edition) [34] to the mothers. The SCID II, which assesses personality disorders, was not administered. Our sample is divided into four subgroups: (a) three clin-ical subgroups were composed by families in which the mothers suffered from Anxiety Disorder (N = 42), 123
  • 3. Depression Disorder (N = 39) or Eating Disorder (N = 44) without a comorbidity disorder and (b) families in which the mothers received no diagnosis (N = 126). We chose not to include mothers who were pursuing treatment to avoid the bias of the effect of a psychotherapeutic intervention over time on the families’ dynamics (N = 9). Consistent with several perspective studies [35], the drop-off rate in the sample at the second time point (T2, 3 years after) was *45 % of the original number of sub-jects. We excluded the families with missing data in their administered questionnaires (N = 54). Thus, at T2 we assessed N = 80 families. The four groups have been then paired by age of the children, age of the mothers and the families’ socio-economic status. The sample presented for the present study is composed of N = 80 families with firstborn children with a mean age of T1 = 2.3 years (SD = 1.1) and T2 = 5.1 (SD = .08). Most of the parents (87 %) were of middle socio-eco-nomic status (SES) [36]. Sixty-eight percent of the parents lived together; 88 % of the fathers and 71 % of the mothers worked; 83 % of the children went to nursery or kinder-garten; 88 % of the children have been breast-fed. All the partners of the mothers recruited for the present study were the biological fathers of the children, and all parents were Caucasian. The mean age of the fathers at T1 was 35.3 years of age (SD = 2.5), and the mean age of the mothers at T1 was 33.2 years of age (SD = 3.1). Tools and Procedures The assessment was administered face-to-face by a group of trained psychologists who visited the families at their home or at mental health clinics. During these visits, a set of self-report and report-form tools were administered, and all the parents signed an informed consent for all the procedures. At the evaluation times (T1 and T2), the parents of both the Clinical Groups and the Non Clinical Group were administered the following tools: SCL-90-R: The Symptom Checklist-90-Revised (SCL- 90-R) is a 90-item self-report symptom inventory aimed to measure psychological symptoms and psychological distress [37]. The main symptom dimensions are Somatization, Obsessive–Compulsive, Inter-personal Sensitivity, Depression, Anxiety, Hostility, Phobic Anxiety, Paranoid Ideation and Psychoticism. The internal coherence tested within a sample of adolescent and adults is satisfying (alpha between .70 and .96), and the clinical cut-off =1 [38] CBCL: The Child Behavior Checklist (CBCL) is a questionnaire filled out by parents and caregivers to assess a child’s abilities and his/her specific behavioral/emotional characteristics. The CBCL/1!-5 [39] is composed of 100 items. The Internalizing Problem Scale consists of the Emotionally Reactive, Anxious/Depressed, Somatic Complaints and Withdrawn Subscales. The Externalizing Problem Scale is composed of the Attention Problems and Aggressive Behavior subscales. The CBCL/1!-5 has a high test–retest reliability and a high internal consistency [39] (Italian validated version and Italian cut-offs, 40). Each parent independently completed the questionnaires at T1 and T2 Analyses Before performing the analyses, the variables’ normality and the congruence between the mothers’ and fathers’ evaluations of the child’s internalizing and externalizing problems were preliminarily ascertained. All the variables were normally distributed, and the correlations among the mothers’ and fathers’ evaluations on the children’s CBCL dimensions were highly and significantly correlated ([.30). Thus, we decided to aggregate the mothers’ and fathers’ scores on the CBCL using mean scores. We began the analyses by examining the stability and change of the children’s internalizing and externalizing problems over time for each group of mothers with a specific disorder (anxiety, depression and eating disorders) and without diagnosis (normative group). Specifically, we examined the mean score differences from Time 1 to Time 2 on the children’s problems by performing repeated measure analyses of variance using time as a within-subject factor and group as a between subject factor. Moreover, a one-way ANOVA was used to test the differences among the groups on internalizing and externalizing dimensions separately for each time. Then, we examined how the fathers’ psychological profiles at T1 were associated with the children’s internalizing and externalizing problems by performing correlation analyses and standard regressions with the fathers’ variables as predictors. Moreover, we examined whether and how the fathers’ SCL-90-R sub-scales were associated with the mothers’ disorders at Time 1 by analyzing the point-biserial correlation coefficients. Finally, to test the influence of the mothers’ disorders and the fathers’ psychological risk on internalizing and exter-nalizing children’s problems, four hierarchical regression analyses were performed separately for the two assessment Child Psychiatry Hum Dev 123
  • 4. points (T1 and T2). In all the regression models, the pre-sence/ absence of each specific disorder of the mother was entered at step 1 and the fathers’ scores on the SCL-90-R subscales were entered at step 2. We also evaluated the influence of the interaction of the mothers’ and fathers’ characteristics on the children’s internalizing and exter-nalizing problems by entering the product of each mothers’ disorders and each fathers’ SCL-90-R subscale at T1 at step 3. These analyses revealed no statistically significant interactions. Results Mothers’ Disorders and Children’s Internalizing and Externalizing Problems The repeated analyses results indicated that the children’s internalizing and externalizing scores were not stable over time [F(1,80) = 74,42; p= at p.001 with an eta square of .48 and F(1,80) = 9,87; p= at p.01 with an eta square of .11, respectively] and that there were significant inter-action between time and group [F(1,80) = 12,31; p= at p.001 with eta square .32 and F(1,80) = 11,81; p= at p.001 with eta square .31, respectively]. More specifi-cally, the multiple comparison tests indicated that the internalizing problems tended to increase over time for all the children. This result was particularly strong in the group of mothers with depression, but the children’s externalizing problems tended to increase over time only in the group of mothers with an eating disorder (Table 1). Analyses on the children’s psychological profile showed significant differences on both internalizing [Time 1: F(3,80) = 26,65; p= at p.001 with an eta square of .50; Time 2: F(3,80) = 30; p= at p.001 with an eta square of .53] and externalizing problems [Time 1: F(3,80) = 37,43; p= at p.001 with an eta square of .58; Time 2: F(3,80) = 34,27; p= at p.001 with an eta square of .56]. Child Psychiatry Hum Dev The significant differences are that (a) the children of mothers of the three clinical groups showed higher inter-nalizing scores than did those of the normative group that (b) the children of mothers with depression and eating disorders showed higher externalizing scores than did those of the normative group or anxiety group. More specifically, at Time 2, the children of mothers with depression showed higher internalizing scores than did other children, but the children of mothers with an eating disorder showed higher externalizing scores than did other children. The normative group showed the lowest internalizing and externalizing problems at both time points. Fathers’ Psychological Profile and Their Child’s Problems Regarding the possible associations between the fathers’ psychopathological risk and their children’s psychological problems at both T1 and T2, correlational analyses attested that (a) interpersonal sensitivity and depression dimensions were significantly and positively associated with both internalizing and externalizing problems, that (b) obses-sive– compulsive and anxiety dimensions were significantly and positively associated with internalizing problems and negatively associated with externalizing problems, and that (c) psychoticism and hostility dimensions were particularly associated with externalizing problems (Table 2). The results of the regression analyses also attested to the influence of the fathers’ psychological scores on their child’s problems, which confirmed some associations. The fathers’ interpersonal sensitivity, depression, anxiety and psychoticism significantly predicted internalizing problems of their child at both Time 1 (45 % of explained variance) and Time 2 (48 % of explained variance). Moreover, at T1, interpersonal sensitivity and psychoticism significantly predicted externalizing problems (51 % of explained vari-ance), and hostility and psychoticism significantly pre-dicted externalizing problems at Time 2. Table 1 Means (SD) of child’s internalizing and externalizing problems by mother’s group at Time 1 and Time 2 Internalizing problems (clinical cut off[16) Externalizing problems (clinical cut off[21) T1 T2 T1–T2 T1 T2 T1–T2 Anxiety disorder 19.6 (6.2) a 21.2 (5.6) a ** 6.31 (5.7) a 5.71 (3.5) a ns. Depression disorder 17.7 (5.5) a 23.1 (6.9) a *** 27.29 (13.0) b 26.54 (14.3) b ns. Eating disorder 17.93 (8.0) a 19.1 (8.0) a * 25.57 (12.5) b 30.20 (15.2) b *** Normative 5.24 (2.7) b 6.9 (3.1) b ** 2.98 (1.7) a 4.21 (2.1) a ns. Total sample 15.12 (8.18) 17.61 (8.8) 15.55 (14.47) 16.62 (15.73) The letters indicate significant differences among the group T1 Time 1, T2 Time 2, T1–T2 difference from Time 1 to Time 2, Fisher F ANOVA at each time, g2 eta square *** p.001; ** p.01; * p.05; ns not significant 123
  • 5. Child Psychiatry Hum Dev Table 2 Regressions and point-biserial correlations on fathers’ dimensions, child’s problems and mothers’ disorders Impact of Mothers’ Disorders and Fathers’ Psychological Profiles on Their Children’s Internalizing and Externalizing Problems The correlation results suggested that there were significant associations between the fathers’ dimensions and the mothers’ disorders. In particular, the fathers’ interpersonal sensitivity and depression were very significantly and positively related to the mothers’ depression disorder. The fathers’ anxiety and obsessive–compulsive symptoms were very significantly and positively related to the mothers’ anxiety disorder. Finally, the fathers’ hostility and psych-oticism were very significantly and positively related to the mothers’ eating disorder (Table 2). As shown in Table 3, all the regression models attested that the mothers’ disorder significantly predicts their chil-dren’s outcomes, concurrently (51 and 60 % of the explained variance for internalizing and externalizing problems, respectively) and longitudinally (54 and 66 % of the explained variance for internalizing and externalizing problems, respectively). In particular, the mothers’ eating disorders and depression significantly and positively influence their children’s externalizing and internalizing problems; instead, the mothers’ anxiety significantly and positively influences only their child’s internalizing prob-lems. Moreover, after controlling the mothers’ disorders, the fathers’ psychological profiles significantly predicted their children’s outcomes (explaining between 09 and 12 % of the variance) with the only exception of exter-nalizing problems at Time 2. In particular, the fathers’ interpersonal sensitivity and anxiety are significantly and positively associated with their child’s internalizing prob-lems and mediate the influence of the mothers’ depression disorder, but the fathers’ obsessive–compulsive dimension is significantly and negatively related to their child’s externalizing problems at Time 1. Discussion The present paper aimed to assess the impact of specific maternal psychopathology on particular frameworks of their children’s functioning by considering the role of paternal psychopathological risk over time. Our results are in line with the international scientific literature that suggests that mothers’ psychopathology can foster their children’s emotional and behavioral problems, which increase in their severity during development [3]. In fact, in our study, the children of mothers with a diagnosis showed significantly higher scores on all internalizing and externalizing dimensions than did the healthy group chil-dren at both Time 1 and Time 2. In particular, the data show that specific diagnoses in the mothers are related to precise maladaptive emotional and behavioral patterns in their children. In Figs. 1, 2 and 3, we present a graphical representation of our main findings from regression analyses: As shown in Fig. 1, we did not find a significant and direct effect of maternal depression on their child’s emo-tional/ behavioral functioning if considered together with the paternal psychopathological risk. Rather, our results show that the fathers’ interpersonal sensitivity predicts their children’s internalizing problems. This result is con-sistent with Lovejoy and colleagues’ work [41] that sug-gested that, in specific family configurations, fathers’ psychopathological risk could have an even more severe Mean (SD) Internalizing problems Externalizing problems Mother disorder T1 T2 T1 T2 Anxiety Depression Eating R b r b r b r b r R r Somatization (F) .48 (29) .28** Ns .26** Ns .10 Ns .15* Ns -.04 .08 .07 Obsessive– compulsive (F) 1.0 (1.0) .35*** Ns .27** Ns -.39*** -.37? -.38*** Ns .80*** -.25* -.30* Interpersonal sensitivity (F) .86 (1.0) .24* .35* .40*** .36* .44*** .36* .37*** Ns -.33** .88*** -.32* Depression (F) .99 (.98) .28** .31* .44*** .43** .46*** Ns .39*** Ns -.25* .90*** -.32* Anxiety (F) .88 (.99) .40*** .57** .32** .56** -.34*** Ns -.33** Ns .79** -.24* -.28* Hostility (F) .88 (.94) .22* Ns .13 Ns .45*** Ns .56*** .31* -.36** -.16 .81*** Phobic anxiety (F) .32 (.37) .06 Ns .09 Ns .16 Ns .17 Ns -.16 .22* -.07 Paranoid ideation (F) .53 (.42) .11 Ns .15 Ns .10 Ns .11 Ns -.20 .26* -.09 Psychoticism (F) .81 (1.0) .22* .38* .13 .39* .41*** .51*** .52*** .51** -.29* -.25* .88*** b regression beta coefficients, F fathers’ dimensions at Time 1, T1 Time 1, T2 Time 2 *** p.001; ** p.01; * p.05; ? p.06 123
  • 6. Table 3 Parents’ impact on their child’s internalizing and externalizing problems at Time 1 and Time 2 Child Psychiatry Hum Dev Internalizing problems Externalizing problems Time 1 Time 2 Time 1 Time 2 b1 b2 R Ch. b1 b2 R Ch. b1 b2 RCh. b1 b2 R Ch. Step 1 Anxiety disorder (M) .67*** .49*** .51*** .59*** .45** .54*** Ns .52*** .60*** Ns Ns .66*** Depression disorder (M) .76*** Ns. .87*** Ns .75*** .67*** .49*** Ns Eating disorder .68*** .66*** .57*** .59*** .73*** .51** .87*** .51*** Step 2 Somatization (F) Ns. .12* Ns. .10* Ns .09* Ns. .06 Obsessive–compulsive (F) Ns. Ns. -.45*** Ns. Interpersonal sensitivity (F) .40** .36* Ns Ns. Depression (F) Ns. Ns. Ns Ns. Anxiety (F) .37? .38* Ns Ns. Hostility (F) Ns. Ns. Ns Ns. Phobic anxiety (F) Ns. Ns. .15? Ns. Paranoid ideation (F) Ns. Ns. Ns Ns. Psychoticism (F) Ns. Ns. Ns Ns. R2 .62*** .64*** .69*** .73*** AR2 .57 .57 .64 .68 R Ch R change, b1 beta at step 1, b2 beta at step 2, R2 = R square, AR adjusted R2, Ns not significant, M mother’s disorders at Time 1 (1 = presence; 0 = absence), F fathers’ psychological dimensions at Time 1 *** p.001; ** p.01; * p.05;? p.06 Fig. 1 Conceptual model—mothers with depression Fig. 2 Conceptual model—mothers with anxiety impact on their children’s psychological functioning than does maternal depression. It is possible that the reciprocally influencing relationship we found between the mothers’ depression and the fathers’ interpersonal sensitivity might express a maladjustment in the couple functioning, which in turn could reflect on the fathers’ capacity for quality interactions with his son or daughter; poor caregiving has been widely recognized to be a predictor of infants’ internalizing (and externalizing) problems [42]. Figure 2 shows that the mothers’ and fathers’ anxiety significantly and directly predicts their children’s internalizing problems. It is important to note that psy-chological/ psychopathological difficulties of mothers and fathers are connected with a bidirectional influence in our sample; thus, we can hypothesize in agreement with the studies of Weissmann et al. [26] that parents often share a specific psychological difficulty whose cumulative weight impairs their child’s emotional and behavioral functioning in the direction of internalizing problems. Figure 3 shows that maternal eating disorders predict externalizing problems in children. Paternal psychoticism does not predict children’s problems, but it is reciprocally 123
  • 7. Child Psychiatry Hum Dev connected to maternal disorders. In this case, it is possible hypothesize that mothers’ eating disorders have such an intense impact on their children’s psychological function-ing that the weight of paternal psychopathological risk is lost. In line with the studies of Sarkadi and colleagues [43], we can suppose that the mother is most likely responsible for feeding the child (with fathers less often involved in the feeding of young children) and that this specific maternal disorder powerfully impacts the child’s emotional and behavioral functioning because the mother–infant dyad interacts every day in supposedly difficult interactions during meals. These results highlight the importance of assessing the whole family (mother, father and children) over time and the significance of an early intervention because our study indicates an increase in children’s maladaptive psycho-logical profiles from T1 to T2 that could be avoided with well-timed clinical work [25]. The interesting bidirectional relationship between maternal and paternal psychopatho-logical symptoms (as discussed above) must be more specifically addressed in a future study because we hypothesize that it influences the general functioning of the family and particularly the parents’ caregiving quality, which in turn is connected to possible maladaptive out-comes in their children. This issue is relevant for the organization of intervention practices that must involve the whole family and assess possible marital maladjustment [44] to better understand how various psychopathological maternal and paternal symptoms can interact and impact the psychological welfare of their children. Our study has several strengths. It considered various maternal diagnostic groups and their effects on their chil-dren’s emotional/behavioral functioning over time, but it also measured the possible mediating effect of paternal psychopathology. Both parents completed the CBCL, but many previous studies included self-report questionnaires completed only by the mother. Our study has some limi-tations. The study has a homogeneous sample, which included only Caucasians of middle socio-economic status with mainly two traditional working parents. Moreover, we did not administer the SCID-II to assess personality dis-orders in the mothers, and we did not evaluate the severity of the mothers’ diagnosis with a specific tool. We did not administer the SCID I to fathers but relied on the SCL-90- R self-report questionnaire, whose scores were not con-firmed by other tools and/or clinical interviews adminis-tered by trained psychologists. We did not directly observe the children’s behavior and characteristics but used a widely used and validated report-form questionnaire. We also did not address possible differences in the psycho-logical functioning of the sons or daughters of mothers with eating disorders or of mothers with other diagnoses as the international literature suggests [45]. These limitations constitute a motivation to continue our research and take samples of mothers with comorbidities into consideration. Summary Several authors suggest that parents’ psychopathology can foster the onset of maladaptive psychological profiles in their children. It has been demonstrated that children’s psychological difficulties tend to increase over time, par-ticularly in families in which the mother suffers from depression, anxiety or eating disorders. It has also been suggested that fathers’ psychopathological risk may be a risk factor for the onset of difficulties in their children. The present study focused on assessing the emotional func-tioning of the children of mothers with various diagnoses and of mothers with no psychological disorder while con-sidering the possible mediating role of the fathers’ psy-chological profiles on their children’s internalizing/ externalizing functioning. We used the SCID I [25], SCL- 90/R [36], and CBCL/1!-5 [39]. The analyses showed that the children’s internalizing and externalizing scores tended to increase from T1 to T2. Maternal psychopathology proved to be strongly related to their children’s maladap-tive profiles. Specifically, the children of mothers with depression showed higher internalizing scores than did children of other groups, and these scores increased from T1 to T2; the children of mothers with eating disorders showed higher and increasing externalizing scores than did other children. The children of mothers with a diagnosis showed significantly higher scores in all internalizing and externalizing dimensions than did the healthy group chil-dren at both Time 1 and Time 2. In particular, the children showed specific maladaptive profiles depending on what diagnosis their mother received. Mothers with depression were more likely to have a withdrawn child, and mothers with eating disorders had a higher probability of having aggressive children. Furthermore, the fathers’ interpersonal Fig. 3 Conceptual model—mothers with eating disorders 123
  • 8. sensitivity, depression, anxiety and psychoticism signifi-cantly predicted internalizing problems of their children at both T1 and T2. Moreover, at T1, the fathers’ interpersonal sensitivity and psychoticism significantly predicted their child’s externalizing problems, and the fathers’ hostility and psychoticism significantly predicted their child’s externalizing problems at T2. References 1. Sanders MR (2002) Parenting interventions and the prevention of serious mental health problems in children. Med J Aust 177(7): S87–S92 2. Douglas J (1995) Behavioral problems in children. Trans. Yasaei M. Tehran: Markaze Nashr Publ, 38 3. Rihai F, Amini F, Salehi Veisi M (2012) Children’s behavioral problems and their relationship with maternal mental health. JJUMS 10:1 4. Bagner DM, Pettit JW, Lewinsohn PM, Seeley JR (2010) Effect of maternal depression on child behavior: a sensitive period? J Am Acad Child Psychiatry 49(7):699–707. doi:10.1016/j.jaac. 2010.03.012 5. 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