1. Lamyaa Al Saidi R2

2. Background
• ACEI have been the cornerstone for treatment
of heart failure and a reduced Ejection
Fraction for nearly 25 years.
• In previous studies, enalapril improved
survival in such patients

3. AIM
Prospective Comparison ARNI (Angiotensin
receptor neprilysin inhibitor LCZ696) with ACEI
(Angiotensin converting enzyme inhibitor) to
determine impact on global mortality and
morbidity in Heart Failure Trial