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University of Medical Technology
Yangon, Myanmar
1. Introduction
2. Gross Anatomy of Knee Joint
3. Osteoarthritis
4. Imaging Procedure
5. Measuring Methods
6. Bony Measurements in Osteoarthritic Knee
7. Conclusion
8. References
Are You Suffering from Knee Pain ?
Your Parents ?
Your Relatives ?
• Some degenerative changes in bones and joints make the
elderly suffer for long period of time, especially knee
pain.
• Although there are numerous causes of knee pain,
Osteoarthritis becomes an increasing and highly
prevalent problem.
• Affects not only on older persons, also on everyone.
• For the patients suffering from knee pain, generally,
plain X-ray examination is the first investigation
method.
1. Introduction
• On the AP projection of knee joint, the standard
radiological signs of osteoarthritis;
-joint space narrowing
-sclerosis of subchondral bone
-osteophytes and
-subchondral cyst formation
• This presentation focuses on-
(1) the sharpening degrees of the tubercles of the
intercondylar eminence of the tibial plateau
(2) the changes in the ratios of tubercle height to width
of tibial plateau in osteoarthritic knee
• According to sex distribution, age distribution and on the
affected side in Myanmar
 Largest synovial joint in the body
 Kind of weight bearing joint
 Two condylar joints between femur and tibia
 A sellar (saddle) joint between patella and femur
 Major surfaces –(1)two femoral condyles
(2)the adjacent surfaces of the superior
aspect of the tibial condyles
2. Gross Anatomy of Knee Joint
 Upper end of the tibia consists of two large condyles with
joint surface superiorly for articulation with the femur
 Larger medial tibial condyle - superior surface is concave
in all directions
 Smaller lateral tibial condyle - convex anteroposteriorly
3. Osteoarthritis @ Osteoarthrosis
 Most common degenerative disease
 Caused by cartilage breakdown and
subsequent bony changes of the joints
 A leading cause of disability among the elderly, even to
young age
 Most Common in Women
Joints Commonly Affected by Osteoarthritis
Ref: Francesco Priolo. (2002). Bones and Joint Imaging in Rheumatic and Orthopedic
Diseases. Italy: GPAnet,
Types of Osteoarthritis
Primary OA - Idiopathic Secondary OA - Posttraumatic
Some Factors:
genetic factors,
hormonal factors,
nutritional factors
biological age
•Developmental, e.g. hip dysplasia,
unequal leg lengths, etc.
•Inflammatory, e.g. rheumatoid
arthritis , spondyloarthropathies
•Infective, e.g. septic arthritis
•Metabolic, e.g. gout, pseudo-gout
•Traumatic or neuropathic
•Occupational (miners, sportsmen)
•Hypermobility syndrome
•Endocrine, e.g. acromegaly
OA Risk Factors
 Excess weight
 Injury
 Certain occupations (Farmers, jackhammer operators,
and mill workers)
 Congenital or developmental deformities
 Hormonal Changes
 Weak thigh muscles (Weak Quadriceps)
 Genetic factors
 Other diseases changing cartilage structure (RA, gout,
pseudogout, and hemochromatosis)
 Low intake of Vitamin C and D
Signs and Symptoms
Pain
Swelling
Decrease in motion at the joint
Stiffness
Formation of bone spurs
Loss of full knee extension
Standard Radiological Signs of Osteoarthritis
Joint space narrowing
Spiking of the tibial tubercles
Sclerosis of subchondral bone
Osteophytes
Subchondral cyst formation
Methods to Examine Knee Osteoarthritis
Physical examination
Imaging methods
 Conventional radiography
 Knee arthrography
 Ultrasound
 Radionuclide scintigraphy
 CT scan
 MRI
Laboratory tests
4. Knee Joint (AP)Imaging Procedure
 Patient Position
 supine on the table, the legs fully extended
 without rotation of pelvis
 Internal Rotation 3 to 5 degrees for a true AP knee
Central Ray
Central ray parallel to articular facets (tibial
plateau)
Perpendicular to image receptor
Center to a point 0.5 inches (1.25 cm) distal
to apex of patella
Source to image receptor (SID)
 Minimum SID - 40 inches
Collimation
 Four-sided collimation to the area of interest
Shielding
Gonadal shielding over reproductive area
Knee Joint AP Radiographs
L
Criteria for Data Collection
Inclusion Criteria Exclusion Criteria
OA knee patients over
the age of 40-year
Patients with operative
knee joint and history of
trauma
Patients with knee pain
due to infection
5. Measuring Methods
To measure the spiking of the tubercles of the
intercondylar eminence of tibial plateau
M° = the angle between the lines intersecting at
the tip of the medial tubercle
L° = the angle between the lines intersecting at
the tip of the lateral tubercle
To calculate the ratios of height of tubercle to
width of tibial plateau
Medial Ratio (MR) = MH : w
Lateral Ratio (LR) = LH : w
6. Bony Measurements in OA Knee
Mean SD Minimum Median Maximum
M° 88.00 16.95 51 88 138
L° 96.07 18.58 50 95 141
Angulations of Tubercles
Ratio of Tubercle Height to Tibial Width
Mean SD Minimum Median Maximum
MR 0.15 0.10 0.01 0.14 0.90
LR 0.13 0.02 0.07 0.13 0.18
Mean Age of Osteoarthritic Knee
Mean SD Maximum Minimum
Age 55.07 12.75 90 40
Angulation in Age Distribution
Age Group M° L°
40-49years 90.74° 90.26°
50-59years 94.33° 101.10°
60-69years 77.07° 98.80°
70-80years 84.47° 94.94°
0
50
100
150
40-49
years
50-59
years
60-69
years
70-80
years
DegreeofTubercle
Spiking
Age Group
Angulation in Age Distribution
M°
L°
Ratio of Tubercle Height to Tibial Width in Age Distribution
Age Group MR LR
40-49years 0.13 0.12
50-59years 0.13 0.12
60-69years 0.15 0.13
70-80years 0.24 0.14
0.1
0.15
0.2
0.25
0.3
40-49 years 50-59 years 60-69 years 70-80 years
Ratio of Tubercle Height to Tibial Width in
Age Distribution
MR
LR
Osteoarthritis in Sex Distribution
Sex No of Patient Percentage
Male 20 29.9
Female 47 70.1
Total 67 100.0
Male,
29.90%
Female,
70.10%
Osteoarthritic Knee in Sex Distribution
Osteoarthritis in Age Distribution
Age Group No of Patient Percentage
40-49years 23 34.3
50-59years 21 31.3
60-69years 15 22.4
70-80years 8 12.0
Total 67 100.0 P=0.954
34%
31%
23%
12%
Osteoarthritis in Age Distribution
40-49years
50-59years
60-69years
70-80years
Affected Side in Sex Distribution
Sex Left Percentage Right Percentage
Male 11 33.33 9 26.47
Female 22 66.67 25 73.53
Total 33 100 34 100
33.33%
26.47%
66.67%
73.53%
Left Right
Affected Side in Sex Distribution
Male Female
7. Conclusion
In osteoarthritic knee joint,
• Medial tubercle spike - 88.00 ± 16.95°
• Lateral tubercle spike - 96.07 ± 18.58°
• Medial ratio - 0.15
• Lateral ratio - 0.13
• Medial tubercle and Lateral Ratio is more affected by OA
changes
• Greatest incidence - 40-49 years of age
• Mean Age - 55.07 ± 12.75
• Disease occurrence - Higher in Female
• Affected Side - Right in Female
- Left in Male
• the sharpening of tubercles of the intercondylar eminence
of the tibial plateau
• the ratio changes of tubercle height to tibial width are
Radiological Features in Osteoarthritis of the Knee Joint
 Ahlback, S. (1968) Osteoarthritis of the knee: a radiographic investigation. Acta
Radiologica-Supplementum, 277, p. 7-72.
 Alexander, C. J. (1990) Osteoarthritis: a review of old myths and current concepts.
Skeletal Radiology, 19, p. 327-333.
 Bontrager, K.L. and Lampignano, J.P. (2010) Text book of radiographic positioning
and related anatomy. 7th ed. Mosby: Jeanne Olson, p. 242.
 Brant, KD. (2005). Osteoarthritis, In: Harrison’s Principles of Internal medicine,
16th Edition, 312: 2036 – 2045.
 Brooks, P. (2003). Inflammation as an important feature of osteoarthritis. Bull
World Health Organ 81:689 – 690.
8. References
Browener, W.S., Newman, T.B., Cummings, S.R., and Hulley, S. B. (2001) Designing
Clinical Research: An Epidemiologic Approach. 2nd ed. Philadelphia: Lippincott Willams &
Wilkins, pp. 65-94.
Cooper (1995). Generalized Osteoarthritis In Women: Pattern of Joint Involvement and
Approach to Definition, MRC Environmental Epidemiology and Rheumatology Unit, St
Thomas Hospital, London, SEI 7EH.
Creamer P & Hochberg MC (1997). Osteoarthritis. Lancet 350:503 – 508.
Ehrlich GE (2003). The rise of osteoarthritis. Bull World Health Organ 81: 630.
Francesco Priolo. (2002). Bones and Joint Imaging in Rheumatic and Orthopedic
Diseases. Italy: GPAnet, p. 67.
Felson DT (1997). Epidemiology of the Rheumatic diseases. In: Arthritis and allied
conditions: A Textbook of Rheumatology. 13th edition. Ed: WJ.Koopman, Williams &
Wilkins, Baltimore.
Felson DT, McLaughlin S & Goggins J (2003). Bone marrow edema and its relation o
progression of knee osteoarthritis. Ann Intern Med 139:330 – 336.
Handy JR (1996). Osteoarthritis in elderly knees. South Med J. 89:1031 – 1035.
 Helmick, C., Felson, D., Lawrence, R. and Gabriel, S. (2008) Estimates of the
Prevalence of Arthritis and Other Rheumatic conditions in the United States. Arthritis
and Rheumatism, 58(1), p. 15-25.
 Kellgren, J.K. and Lawrence, J.S. (1957) Radiological assessment of osteoarthosis.
Annals of Rheumatic Diseases, (16), p. 491-502.
 Keuttner and Goldberg. (1995) Osteoarthritis Disorders. American Academy of
Orthopaedic Surgeons, p. 21-25.
 Khin-Maung-Win Dr. (1987) Study of non-traumatic synovitis of the knee joint. M.
Sc. Dissertation. University of Medicine, Myanmar, p. 53-54.
 Khin-Thu-Zar-Myaing. (2010) Effectiveness of taping the patella in management of
osteoarthritis of the knee. M. Sc. Dissertation. University of Medical Technology,
Myanmar, p. 22 to 24.
 Lawrence, R. C., Helmick, C. G., Amett, F. C., Deyo, R. A., Felson, David T., Giannini,
E. H., Heyse, S. P. Hirsch, R., Hochberg, Marc C., Hunder, G. G., Liang, M. H.,
Pillemer, S. R., Steen, V. D., and Wolfe, F. (1998) Estimates of the prevalence of
arthritis and selected musculoskeletal disorders in the United States. Arthritis and
Rheumatism, 41(5), p. 778-799.
 Ledingham J, Refan M, Jones A & Doherty M (1993). Radiographic patterns and
associations of osteoarthritis of the knee in patients referred to hospital. Ann Rheum Dis;
2:1520-6.
 Machin, D., Capmbell, M., Fayers, P., and Pinol, A. (1997) Sample Size Tables for
Clinical Studies. 2nd ed. Blackwell Science. Malden, MA.
 McLeod, W. D., Moschi, A., Andrews, J. R. and Hughston, J. C. (1977) Tibial plateau
topography. American Journal of Sports Medicine, (5), p. 13-18.
 Netter, F. H. (1996) The Ciba Collection of Medical Illustration Volume 8. Part 1, 4th ed,
p. 94-96.
 Ohnmar Sein Myint. (2010) Plain Radiographic Study on Symphysis Pubis Width in
Children. M.Sc. Dissertation. University of Medical Technology, Myanmar, p. 16-19.
 Parmet, S. (2003) Osteoarthritic knee. The journals of American medical association,
289 (8), p. 1068.
 Pawa, S., Berry, M., Chowdhury, V., Mukhopadhyay, S. and Suri, S. (2005) Diagnostic
Radiology. 2nd ed. New Delhi: Jaypee Brothers, p. 170-198.
 Reiff, D. B., Heron, C. W. and Stoker, D. J. (1991) Spiking of the tubercles of the
intercondylar eminence of the tibial plateau in osteoarthritis. The British Journal of
Radiology, (64), p. 915-917.
 Resnick, D. and Niwayama, G. (1988) Diagnosis of bone and joint disorders. 2nd ed.
Philadelphia: WB Saunders Co, p. 1448.
 San-San-Nwe. (2005) A comparative study on effectiveness of isotonic versus isomeric
resistance exercise in management of osteoarthritis of the knee. M.Sc. Dissertation.
University of Medical Technology, Myanmar, p. 21.
 Sinnatamby, C. S. (2006) Last’s anatomy. 11th ed. London: Churchill Livingstone, p.
139-143.
 Sithu Dr (2003) A study of synovial fluid analysis in assessment of the diseases of the
knee joint. M.Sc Dissertation. University of Medicine, Myanmar, p. 39-52.
 Spector, T. D., Hart, D. J. and Doyle, D. V. (1996) Incidence and progression of
osteoarthritis in women with unilateral knee disease in the general population: the effect
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 Sutton, D. (2003) Textbook of radiology and imaging. 7th ed. Edinburgh: Churchill
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Radiological study of oa knee in mm

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Radiological study of oa knee in mm

  • 1.
  • 2. University of Medical Technology Yangon, Myanmar
  • 3. 1. Introduction 2. Gross Anatomy of Knee Joint 3. Osteoarthritis 4. Imaging Procedure 5. Measuring Methods 6. Bony Measurements in Osteoarthritic Knee 7. Conclusion 8. References
  • 4. Are You Suffering from Knee Pain ? Your Parents ? Your Relatives ?
  • 5. • Some degenerative changes in bones and joints make the elderly suffer for long period of time, especially knee pain. • Although there are numerous causes of knee pain, Osteoarthritis becomes an increasing and highly prevalent problem. • Affects not only on older persons, also on everyone. • For the patients suffering from knee pain, generally, plain X-ray examination is the first investigation method. 1. Introduction
  • 6. • On the AP projection of knee joint, the standard radiological signs of osteoarthritis; -joint space narrowing -sclerosis of subchondral bone -osteophytes and -subchondral cyst formation
  • 7. • This presentation focuses on- (1) the sharpening degrees of the tubercles of the intercondylar eminence of the tibial plateau (2) the changes in the ratios of tubercle height to width of tibial plateau in osteoarthritic knee • According to sex distribution, age distribution and on the affected side in Myanmar
  • 8.  Largest synovial joint in the body  Kind of weight bearing joint  Two condylar joints between femur and tibia  A sellar (saddle) joint between patella and femur  Major surfaces –(1)two femoral condyles (2)the adjacent surfaces of the superior aspect of the tibial condyles 2. Gross Anatomy of Knee Joint
  • 9.  Upper end of the tibia consists of two large condyles with joint surface superiorly for articulation with the femur  Larger medial tibial condyle - superior surface is concave in all directions  Smaller lateral tibial condyle - convex anteroposteriorly
  • 10. 3. Osteoarthritis @ Osteoarthrosis  Most common degenerative disease  Caused by cartilage breakdown and subsequent bony changes of the joints  A leading cause of disability among the elderly, even to young age  Most Common in Women
  • 11. Joints Commonly Affected by Osteoarthritis Ref: Francesco Priolo. (2002). Bones and Joint Imaging in Rheumatic and Orthopedic Diseases. Italy: GPAnet,
  • 12. Types of Osteoarthritis Primary OA - Idiopathic Secondary OA - Posttraumatic Some Factors: genetic factors, hormonal factors, nutritional factors biological age •Developmental, e.g. hip dysplasia, unequal leg lengths, etc. •Inflammatory, e.g. rheumatoid arthritis , spondyloarthropathies •Infective, e.g. septic arthritis •Metabolic, e.g. gout, pseudo-gout •Traumatic or neuropathic •Occupational (miners, sportsmen) •Hypermobility syndrome •Endocrine, e.g. acromegaly
  • 13. OA Risk Factors  Excess weight  Injury  Certain occupations (Farmers, jackhammer operators, and mill workers)  Congenital or developmental deformities  Hormonal Changes
  • 14.  Weak thigh muscles (Weak Quadriceps)  Genetic factors  Other diseases changing cartilage structure (RA, gout, pseudogout, and hemochromatosis)  Low intake of Vitamin C and D
  • 15. Signs and Symptoms Pain Swelling Decrease in motion at the joint Stiffness Formation of bone spurs Loss of full knee extension
  • 16. Standard Radiological Signs of Osteoarthritis Joint space narrowing Spiking of the tibial tubercles Sclerosis of subchondral bone Osteophytes Subchondral cyst formation
  • 17. Methods to Examine Knee Osteoarthritis Physical examination Imaging methods  Conventional radiography  Knee arthrography  Ultrasound  Radionuclide scintigraphy  CT scan  MRI Laboratory tests
  • 18. 4. Knee Joint (AP)Imaging Procedure  Patient Position  supine on the table, the legs fully extended  without rotation of pelvis  Internal Rotation 3 to 5 degrees for a true AP knee
  • 19. Central Ray Central ray parallel to articular facets (tibial plateau) Perpendicular to image receptor Center to a point 0.5 inches (1.25 cm) distal to apex of patella Source to image receptor (SID)  Minimum SID - 40 inches Collimation  Four-sided collimation to the area of interest
  • 21. Knee Joint AP Radiographs L
  • 22. Criteria for Data Collection Inclusion Criteria Exclusion Criteria OA knee patients over the age of 40-year Patients with operative knee joint and history of trauma Patients with knee pain due to infection
  • 23. 5. Measuring Methods To measure the spiking of the tubercles of the intercondylar eminence of tibial plateau M° = the angle between the lines intersecting at the tip of the medial tubercle L° = the angle between the lines intersecting at the tip of the lateral tubercle
  • 24. To calculate the ratios of height of tubercle to width of tibial plateau Medial Ratio (MR) = MH : w Lateral Ratio (LR) = LH : w
  • 25. 6. Bony Measurements in OA Knee Mean SD Minimum Median Maximum M° 88.00 16.95 51 88 138 L° 96.07 18.58 50 95 141 Angulations of Tubercles Ratio of Tubercle Height to Tibial Width Mean SD Minimum Median Maximum MR 0.15 0.10 0.01 0.14 0.90 LR 0.13 0.02 0.07 0.13 0.18 Mean Age of Osteoarthritic Knee Mean SD Maximum Minimum Age 55.07 12.75 90 40
  • 26. Angulation in Age Distribution Age Group M° L° 40-49years 90.74° 90.26° 50-59years 94.33° 101.10° 60-69years 77.07° 98.80° 70-80years 84.47° 94.94° 0 50 100 150 40-49 years 50-59 years 60-69 years 70-80 years DegreeofTubercle Spiking Age Group Angulation in Age Distribution M° L°
  • 27. Ratio of Tubercle Height to Tibial Width in Age Distribution Age Group MR LR 40-49years 0.13 0.12 50-59years 0.13 0.12 60-69years 0.15 0.13 70-80years 0.24 0.14 0.1 0.15 0.2 0.25 0.3 40-49 years 50-59 years 60-69 years 70-80 years Ratio of Tubercle Height to Tibial Width in Age Distribution MR LR
  • 28. Osteoarthritis in Sex Distribution Sex No of Patient Percentage Male 20 29.9 Female 47 70.1 Total 67 100.0 Male, 29.90% Female, 70.10% Osteoarthritic Knee in Sex Distribution
  • 29. Osteoarthritis in Age Distribution Age Group No of Patient Percentage 40-49years 23 34.3 50-59years 21 31.3 60-69years 15 22.4 70-80years 8 12.0 Total 67 100.0 P=0.954 34% 31% 23% 12% Osteoarthritis in Age Distribution 40-49years 50-59years 60-69years 70-80years
  • 30. Affected Side in Sex Distribution Sex Left Percentage Right Percentage Male 11 33.33 9 26.47 Female 22 66.67 25 73.53 Total 33 100 34 100 33.33% 26.47% 66.67% 73.53% Left Right Affected Side in Sex Distribution Male Female
  • 31. 7. Conclusion In osteoarthritic knee joint, • Medial tubercle spike - 88.00 ± 16.95° • Lateral tubercle spike - 96.07 ± 18.58° • Medial ratio - 0.15 • Lateral ratio - 0.13 • Medial tubercle and Lateral Ratio is more affected by OA changes • Greatest incidence - 40-49 years of age • Mean Age - 55.07 ± 12.75
  • 32. • Disease occurrence - Higher in Female • Affected Side - Right in Female - Left in Male • the sharpening of tubercles of the intercondylar eminence of the tibial plateau • the ratio changes of tubercle height to tibial width are Radiological Features in Osteoarthritis of the Knee Joint
  • 33.  Ahlback, S. (1968) Osteoarthritis of the knee: a radiographic investigation. Acta Radiologica-Supplementum, 277, p. 7-72.  Alexander, C. J. (1990) Osteoarthritis: a review of old myths and current concepts. Skeletal Radiology, 19, p. 327-333.  Bontrager, K.L. and Lampignano, J.P. (2010) Text book of radiographic positioning and related anatomy. 7th ed. Mosby: Jeanne Olson, p. 242.  Brant, KD. (2005). Osteoarthritis, In: Harrison’s Principles of Internal medicine, 16th Edition, 312: 2036 – 2045.  Brooks, P. (2003). Inflammation as an important feature of osteoarthritis. Bull World Health Organ 81:689 – 690. 8. References
  • 34. Browener, W.S., Newman, T.B., Cummings, S.R., and Hulley, S. B. (2001) Designing Clinical Research: An Epidemiologic Approach. 2nd ed. Philadelphia: Lippincott Willams & Wilkins, pp. 65-94. Cooper (1995). Generalized Osteoarthritis In Women: Pattern of Joint Involvement and Approach to Definition, MRC Environmental Epidemiology and Rheumatology Unit, St Thomas Hospital, London, SEI 7EH. Creamer P & Hochberg MC (1997). Osteoarthritis. Lancet 350:503 – 508. Ehrlich GE (2003). The rise of osteoarthritis. Bull World Health Organ 81: 630. Francesco Priolo. (2002). Bones and Joint Imaging in Rheumatic and Orthopedic Diseases. Italy: GPAnet, p. 67. Felson DT (1997). Epidemiology of the Rheumatic diseases. In: Arthritis and allied conditions: A Textbook of Rheumatology. 13th edition. Ed: WJ.Koopman, Williams & Wilkins, Baltimore. Felson DT, McLaughlin S & Goggins J (2003). Bone marrow edema and its relation o progression of knee osteoarthritis. Ann Intern Med 139:330 – 336. Handy JR (1996). Osteoarthritis in elderly knees. South Med J. 89:1031 – 1035.
  • 35.  Helmick, C., Felson, D., Lawrence, R. and Gabriel, S. (2008) Estimates of the Prevalence of Arthritis and Other Rheumatic conditions in the United States. Arthritis and Rheumatism, 58(1), p. 15-25.  Kellgren, J.K. and Lawrence, J.S. (1957) Radiological assessment of osteoarthosis. Annals of Rheumatic Diseases, (16), p. 491-502.  Keuttner and Goldberg. (1995) Osteoarthritis Disorders. American Academy of Orthopaedic Surgeons, p. 21-25.  Khin-Maung-Win Dr. (1987) Study of non-traumatic synovitis of the knee joint. M. Sc. Dissertation. University of Medicine, Myanmar, p. 53-54.  Khin-Thu-Zar-Myaing. (2010) Effectiveness of taping the patella in management of osteoarthritis of the knee. M. Sc. Dissertation. University of Medical Technology, Myanmar, p. 22 to 24.
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