5. • Some degenerative changes in bones and joints make the
elderly suffer for long period of time, especially knee
pain.
• Although there are numerous causes of knee pain,
Osteoarthritis becomes an increasing and highly
prevalent problem.
• Affects not only on older persons, also on everyone.
• For the patients suffering from knee pain, generally,
plain X-ray examination is the first investigation
method.
1. Introduction
6. • On the AP projection of knee joint, the standard
radiological signs of osteoarthritis;
-joint space narrowing
-sclerosis of subchondral bone
-osteophytes and
-subchondral cyst formation
7. • This presentation focuses on-
(1) the sharpening degrees of the tubercles of the
intercondylar eminence of the tibial plateau
(2) the changes in the ratios of tubercle height to width
of tibial plateau in osteoarthritic knee
• According to sex distribution, age distribution and on the
affected side in Myanmar
8. Largest synovial joint in the body
Kind of weight bearing joint
Two condylar joints between femur and tibia
A sellar (saddle) joint between patella and femur
Major surfaces –(1)two femoral condyles
(2)the adjacent surfaces of the superior
aspect of the tibial condyles
2. Gross Anatomy of Knee Joint
9. Upper end of the tibia consists of two large condyles with
joint surface superiorly for articulation with the femur
Larger medial tibial condyle - superior surface is concave
in all directions
Smaller lateral tibial condyle - convex anteroposteriorly
10. 3. Osteoarthritis @ Osteoarthrosis
Most common degenerative disease
Caused by cartilage breakdown and
subsequent bony changes of the joints
A leading cause of disability among the elderly, even to
young age
Most Common in Women
11. Joints Commonly Affected by Osteoarthritis
Ref: Francesco Priolo. (2002). Bones and Joint Imaging in Rheumatic and Orthopedic
Diseases. Italy: GPAnet,
12. Types of Osteoarthritis
Primary OA - Idiopathic Secondary OA - Posttraumatic
Some Factors:
genetic factors,
hormonal factors,
nutritional factors
biological age
•Developmental, e.g. hip dysplasia,
unequal leg lengths, etc.
•Inflammatory, e.g. rheumatoid
arthritis , spondyloarthropathies
•Infective, e.g. septic arthritis
•Metabolic, e.g. gout, pseudo-gout
•Traumatic or neuropathic
•Occupational (miners, sportsmen)
•Hypermobility syndrome
•Endocrine, e.g. acromegaly
13. OA Risk Factors
Excess weight
Injury
Certain occupations (Farmers, jackhammer operators,
and mill workers)
Congenital or developmental deformities
Hormonal Changes
14. Weak thigh muscles (Weak Quadriceps)
Genetic factors
Other diseases changing cartilage structure (RA, gout,
pseudogout, and hemochromatosis)
Low intake of Vitamin C and D
16. Standard Radiological Signs of Osteoarthritis
Joint space narrowing
Spiking of the tibial tubercles
Sclerosis of subchondral bone
Osteophytes
Subchondral cyst formation
18. 4. Knee Joint (AP)Imaging Procedure
Patient Position
supine on the table, the legs fully extended
without rotation of pelvis
Internal Rotation 3 to 5 degrees for a true AP knee
19. Central Ray
Central ray parallel to articular facets (tibial
plateau)
Perpendicular to image receptor
Center to a point 0.5 inches (1.25 cm) distal
to apex of patella
Source to image receptor (SID)
Minimum SID - 40 inches
Collimation
Four-sided collimation to the area of interest
22. Criteria for Data Collection
Inclusion Criteria Exclusion Criteria
OA knee patients over
the age of 40-year
Patients with operative
knee joint and history of
trauma
Patients with knee pain
due to infection
23. 5. Measuring Methods
To measure the spiking of the tubercles of the
intercondylar eminence of tibial plateau
M° = the angle between the lines intersecting at
the tip of the medial tubercle
L° = the angle between the lines intersecting at
the tip of the lateral tubercle
24. To calculate the ratios of height of tubercle to
width of tibial plateau
Medial Ratio (MR) = MH : w
Lateral Ratio (LR) = LH : w
25. 6. Bony Measurements in OA Knee
Mean SD Minimum Median Maximum
M° 88.00 16.95 51 88 138
L° 96.07 18.58 50 95 141
Angulations of Tubercles
Ratio of Tubercle Height to Tibial Width
Mean SD Minimum Median Maximum
MR 0.15 0.10 0.01 0.14 0.90
LR 0.13 0.02 0.07 0.13 0.18
Mean Age of Osteoarthritic Knee
Mean SD Maximum Minimum
Age 55.07 12.75 90 40
26. Angulation in Age Distribution
Age Group M° L°
40-49years 90.74° 90.26°
50-59years 94.33° 101.10°
60-69years 77.07° 98.80°
70-80years 84.47° 94.94°
0
50
100
150
40-49
years
50-59
years
60-69
years
70-80
years
DegreeofTubercle
Spiking
Age Group
Angulation in Age Distribution
M°
L°
27. Ratio of Tubercle Height to Tibial Width in Age Distribution
Age Group MR LR
40-49years 0.13 0.12
50-59years 0.13 0.12
60-69years 0.15 0.13
70-80years 0.24 0.14
0.1
0.15
0.2
0.25
0.3
40-49 years 50-59 years 60-69 years 70-80 years
Ratio of Tubercle Height to Tibial Width in
Age Distribution
MR
LR
28. Osteoarthritis in Sex Distribution
Sex No of Patient Percentage
Male 20 29.9
Female 47 70.1
Total 67 100.0
Male,
29.90%
Female,
70.10%
Osteoarthritic Knee in Sex Distribution
29. Osteoarthritis in Age Distribution
Age Group No of Patient Percentage
40-49years 23 34.3
50-59years 21 31.3
60-69years 15 22.4
70-80years 8 12.0
Total 67 100.0 P=0.954
34%
31%
23%
12%
Osteoarthritis in Age Distribution
40-49years
50-59years
60-69years
70-80years
30. Affected Side in Sex Distribution
Sex Left Percentage Right Percentage
Male 11 33.33 9 26.47
Female 22 66.67 25 73.53
Total 33 100 34 100
33.33%
26.47%
66.67%
73.53%
Left Right
Affected Side in Sex Distribution
Male Female
31. 7. Conclusion
In osteoarthritic knee joint,
• Medial tubercle spike - 88.00 ± 16.95°
• Lateral tubercle spike - 96.07 ± 18.58°
• Medial ratio - 0.15
• Lateral ratio - 0.13
• Medial tubercle and Lateral Ratio is more affected by OA
changes
• Greatest incidence - 40-49 years of age
• Mean Age - 55.07 ± 12.75
32. • Disease occurrence - Higher in Female
• Affected Side - Right in Female
- Left in Male
• the sharpening of tubercles of the intercondylar eminence
of the tibial plateau
• the ratio changes of tubercle height to tibial width are
Radiological Features in Osteoarthritis of the Knee Joint
33. Ahlback, S. (1968) Osteoarthritis of the knee: a radiographic investigation. Acta
Radiologica-Supplementum, 277, p. 7-72.
Alexander, C. J. (1990) Osteoarthritis: a review of old myths and current concepts.
Skeletal Radiology, 19, p. 327-333.
Bontrager, K.L. and Lampignano, J.P. (2010) Text book of radiographic positioning
and related anatomy. 7th ed. Mosby: Jeanne Olson, p. 242.
Brant, KD. (2005). Osteoarthritis, In: Harrison’s Principles of Internal medicine,
16th Edition, 312: 2036 – 2045.
Brooks, P. (2003). Inflammation as an important feature of osteoarthritis. Bull
World Health Organ 81:689 – 690.
8. References
34. Browener, W.S., Newman, T.B., Cummings, S.R., and Hulley, S. B. (2001) Designing
Clinical Research: An Epidemiologic Approach. 2nd ed. Philadelphia: Lippincott Willams &
Wilkins, pp. 65-94.
Cooper (1995). Generalized Osteoarthritis In Women: Pattern of Joint Involvement and
Approach to Definition, MRC Environmental Epidemiology and Rheumatology Unit, St
Thomas Hospital, London, SEI 7EH.
Creamer P & Hochberg MC (1997). Osteoarthritis. Lancet 350:503 – 508.
Ehrlich GE (2003). The rise of osteoarthritis. Bull World Health Organ 81: 630.
Francesco Priolo. (2002). Bones and Joint Imaging in Rheumatic and Orthopedic
Diseases. Italy: GPAnet, p. 67.
Felson DT (1997). Epidemiology of the Rheumatic diseases. In: Arthritis and allied
conditions: A Textbook of Rheumatology. 13th edition. Ed: WJ.Koopman, Williams &
Wilkins, Baltimore.
Felson DT, McLaughlin S & Goggins J (2003). Bone marrow edema and its relation o
progression of knee osteoarthritis. Ann Intern Med 139:330 – 336.
Handy JR (1996). Osteoarthritis in elderly knees. South Med J. 89:1031 – 1035.
35. Helmick, C., Felson, D., Lawrence, R. and Gabriel, S. (2008) Estimates of the
Prevalence of Arthritis and Other Rheumatic conditions in the United States. Arthritis
and Rheumatism, 58(1), p. 15-25.
Kellgren, J.K. and Lawrence, J.S. (1957) Radiological assessment of osteoarthosis.
Annals of Rheumatic Diseases, (16), p. 491-502.
Keuttner and Goldberg. (1995) Osteoarthritis Disorders. American Academy of
Orthopaedic Surgeons, p. 21-25.
Khin-Maung-Win Dr. (1987) Study of non-traumatic synovitis of the knee joint. M.
Sc. Dissertation. University of Medicine, Myanmar, p. 53-54.
Khin-Thu-Zar-Myaing. (2010) Effectiveness of taping the patella in management of
osteoarthritis of the knee. M. Sc. Dissertation. University of Medical Technology,
Myanmar, p. 22 to 24.
36. Lawrence, R. C., Helmick, C. G., Amett, F. C., Deyo, R. A., Felson, David T., Giannini,
E. H., Heyse, S. P. Hirsch, R., Hochberg, Marc C., Hunder, G. G., Liang, M. H.,
Pillemer, S. R., Steen, V. D., and Wolfe, F. (1998) Estimates of the prevalence of
arthritis and selected musculoskeletal disorders in the United States. Arthritis and
Rheumatism, 41(5), p. 778-799.
Ledingham J, Refan M, Jones A & Doherty M (1993). Radiographic patterns and
associations of osteoarthritis of the knee in patients referred to hospital. Ann Rheum Dis;
2:1520-6.
Machin, D., Capmbell, M., Fayers, P., and Pinol, A. (1997) Sample Size Tables for
Clinical Studies. 2nd ed. Blackwell Science. Malden, MA.
McLeod, W. D., Moschi, A., Andrews, J. R. and Hughston, J. C. (1977) Tibial plateau
topography. American Journal of Sports Medicine, (5), p. 13-18.
Netter, F. H. (1996) The Ciba Collection of Medical Illustration Volume 8. Part 1, 4th ed,
p. 94-96.
37. Ohnmar Sein Myint. (2010) Plain Radiographic Study on Symphysis Pubis Width in
Children. M.Sc. Dissertation. University of Medical Technology, Myanmar, p. 16-19.
Parmet, S. (2003) Osteoarthritic knee. The journals of American medical association,
289 (8), p. 1068.
Pawa, S., Berry, M., Chowdhury, V., Mukhopadhyay, S. and Suri, S. (2005) Diagnostic
Radiology. 2nd ed. New Delhi: Jaypee Brothers, p. 170-198.
Reiff, D. B., Heron, C. W. and Stoker, D. J. (1991) Spiking of the tubercles of the
intercondylar eminence of the tibial plateau in osteoarthritis. The British Journal of
Radiology, (64), p. 915-917.
Resnick, D. and Niwayama, G. (1988) Diagnosis of bone and joint disorders. 2nd ed.
Philadelphia: WB Saunders Co, p. 1448.
San-San-Nwe. (2005) A comparative study on effectiveness of isotonic versus isomeric
resistance exercise in management of osteoarthritis of the knee. M.Sc. Dissertation.
University of Medical Technology, Myanmar, p. 21.
38. Sinnatamby, C. S. (2006) Last’s anatomy. 11th ed. London: Churchill Livingstone, p.
139-143.
Sithu Dr (2003) A study of synovial fluid analysis in assessment of the diseases of the
knee joint. M.Sc Dissertation. University of Medicine, Myanmar, p. 39-52.
Spector, T. D., Hart, D. J. and Doyle, D. V. (1996) Incidence and progression of
osteoarthritis in women with unilateral knee disease in the general population: the effect
of obesity. Annals of Rheumatic Diseases, (53), p. 565-568.
Sutton, D. (2003) Textbook of radiology and imaging. 7th ed. Edinburgh: Churchill
Livingstone, p. 1225.
Tardieu, C. (1981) Morpho-functional analysis of the articular surfaces of the knee joint
in primates. In Primate Evolutionary Biology. p. 68-80. [n.p.]
Thitinan, S. (2009) Osteoarthritis. American College of Rheumatology. p. 3.