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ANATOMY AND PHYSIOLOGY OF
URINARY BLADDER
DR K R SHARMA
ANATOMY OF URINARY BLADDER
Introduction
• The urinary bladder is a muscular organ which
lies in the anterior part of pelvic cavity and helps in
the storage of urine.
• Shape, size and position of bladder varies according
to the amount of urine contained in it.
• An empty bladder lies entirely within the pelvis
but as it fills it extends into abdominal cavity.
• Empty bladder-tetrahedral
• Filled bladder- oval shaed
GROSS FEATURES
• An empty bladder is tetrahedral in shape &
has:
• 1. Apex
• 2. Base or fundus
• 3. Neck
• 4. 3 surfaces: superior, right & left
inferolateral.
• 5. 4 borders: anterior, posterior & 2 lateral
lateral borders.
In female: Vagina and cervix of
the uterus.
Neck: Inferior and most fixed part.
In male: Related to prostate.
Surrounded by smooth muscle fibres
which form preprostatic sphincter.
In female: Related to pelvic fascia.
Puboprostatic ligaments in male
& pubovesical ligaments in
female.
• The ureters open at the
posterolateral angle of the trigone.
• Uvula vesicae: It is a small
elevation on the trigone posterior
to the urethral orifice produced by
median lobe of prostate.
BLOOD SUPPLY OF URINARY BLADDER
• ARTERIAL-
- superior,
middle, and
inferior vesicle artery
branch of ant. trunk of internal iliac artery
-banches from obturator and inferior gluteal
artery
In females- uterine and vaginal artery also send
branches
Venous and lymphatics drainage
• Venous
Surrounding the bladder is a rich plexus of veins
that ultimately empties into internal iliac veins
lymhatics- drain into
-vesical
-external iliac
-internal iliac
-common iliac lymph node
PHYSIOLOGY OF URINARY BLADDER
NERVE SUPPLY
• SYMPATHETIC: CENTRE: T11-L2
SUPPLY THROUGH: • SYMPATHETIC CHAIN
GANGLIA-PREVERTEBRAL GANGLIA-HYPOGASTRIC
AND PELVIC PLEXUS – INFERIOR MESENTRIC
GANGLION –POST GANGLIONIC FIBRES FUNCTION:
• VIA Β3-ADRENERGIC RECEPTORS -INHIBITION
AND RELAXATION OF THE DETRUSSOR MUSCLE.
• VIA ALPHA1 RECEPTORS CAUSES CONTRACTION OF
INTERNAL SPHINCTER
• FACILITATE BLADDER STORAGE AND CONTINENCE
Conti..
PARASYMPATHETIC:
• • CENTRE: S2-S4
• • SUPPLY THROUGH: PELVIC SPLANCHNIC NERVES
• END IN : GANGLIA IN BLADDER WALL •
NEUROTRANSMITTER : ACH VIA M2, M3 •
FUNCTION: CHOLINERGIC TRANSMISSION IS THE
MAJOR EXCITATORY MECHANISM • M2 AND M3
ON DETRUSSOR SMOOTH MUSCLE INITIATES
BLADDER DETRUSSOR CONTRACTION
• AND INTERNAL SPHINCTER RELAXATION VIA
NITRIC OXIDE
SOMATIC :
• CENTRE: ONUF’S NUCLEUS S2-S4
• SUPPLY THROUGH: PUDENDAL
NERVES
• FUNCTION : CONTROLS THE
EXTERNAL SPHINCTER
Cortical and brain stem centre
• Cortical centre- 2nd frontal gyrus paracentral
lobule
- inhibitory to pontine centre
Brain stem centre- barrington nucleus
-coordinating centre
- facilitatory to micturition
-synchronization and maintanance of
sustained contraction to complete evacuation
filling
• Sympathetic stimulated-internal sphinctor
contracted
• Parasympathetic inhibited- detruser relaxed
voiding
• Afferent from bladder
mucosa –pain, touch, temprature
detruser ms and lamina propria –strech
receptor
these afferent passes via inferior
hypogastric plexus
Then spinal micturition reflex comes in play
controlled by higher centres.
THANK YOU ….

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Anatomy and Physiology of the Urinary Bladder

  • 1. ANATOMY AND PHYSIOLOGY OF URINARY BLADDER DR K R SHARMA
  • 3. Introduction • The urinary bladder is a muscular organ which lies in the anterior part of pelvic cavity and helps in the storage of urine. • Shape, size and position of bladder varies according to the amount of urine contained in it. • An empty bladder lies entirely within the pelvis but as it fills it extends into abdominal cavity. • Empty bladder-tetrahedral • Filled bladder- oval shaed
  • 4. GROSS FEATURES • An empty bladder is tetrahedral in shape & has: • 1. Apex • 2. Base or fundus • 3. Neck • 4. 3 surfaces: superior, right & left inferolateral. • 5. 4 borders: anterior, posterior & 2 lateral lateral borders.
  • 5.
  • 6. In female: Vagina and cervix of the uterus.
  • 7. Neck: Inferior and most fixed part. In male: Related to prostate. Surrounded by smooth muscle fibres which form preprostatic sphincter. In female: Related to pelvic fascia.
  • 8. Puboprostatic ligaments in male & pubovesical ligaments in female.
  • 9.
  • 10. • The ureters open at the posterolateral angle of the trigone. • Uvula vesicae: It is a small elevation on the trigone posterior to the urethral orifice produced by median lobe of prostate.
  • 11.
  • 12.
  • 13.
  • 14.
  • 15. BLOOD SUPPLY OF URINARY BLADDER • ARTERIAL- - superior, middle, and inferior vesicle artery branch of ant. trunk of internal iliac artery -banches from obturator and inferior gluteal artery In females- uterine and vaginal artery also send branches
  • 16. Venous and lymphatics drainage • Venous Surrounding the bladder is a rich plexus of veins that ultimately empties into internal iliac veins lymhatics- drain into -vesical -external iliac -internal iliac -common iliac lymph node
  • 18. NERVE SUPPLY • SYMPATHETIC: CENTRE: T11-L2 SUPPLY THROUGH: • SYMPATHETIC CHAIN GANGLIA-PREVERTEBRAL GANGLIA-HYPOGASTRIC AND PELVIC PLEXUS – INFERIOR MESENTRIC GANGLION –POST GANGLIONIC FIBRES FUNCTION: • VIA Β3-ADRENERGIC RECEPTORS -INHIBITION AND RELAXATION OF THE DETRUSSOR MUSCLE. • VIA ALPHA1 RECEPTORS CAUSES CONTRACTION OF INTERNAL SPHINCTER • FACILITATE BLADDER STORAGE AND CONTINENCE
  • 19. Conti.. PARASYMPATHETIC: • • CENTRE: S2-S4 • • SUPPLY THROUGH: PELVIC SPLANCHNIC NERVES • END IN : GANGLIA IN BLADDER WALL • NEUROTRANSMITTER : ACH VIA M2, M3 • FUNCTION: CHOLINERGIC TRANSMISSION IS THE MAJOR EXCITATORY MECHANISM • M2 AND M3 ON DETRUSSOR SMOOTH MUSCLE INITIATES BLADDER DETRUSSOR CONTRACTION • AND INTERNAL SPHINCTER RELAXATION VIA NITRIC OXIDE
  • 20. SOMATIC : • CENTRE: ONUF’S NUCLEUS S2-S4 • SUPPLY THROUGH: PUDENDAL NERVES • FUNCTION : CONTROLS THE EXTERNAL SPHINCTER
  • 21.
  • 22. Cortical and brain stem centre • Cortical centre- 2nd frontal gyrus paracentral lobule - inhibitory to pontine centre Brain stem centre- barrington nucleus -coordinating centre - facilitatory to micturition -synchronization and maintanance of sustained contraction to complete evacuation
  • 23. filling • Sympathetic stimulated-internal sphinctor contracted • Parasympathetic inhibited- detruser relaxed
  • 24. voiding • Afferent from bladder mucosa –pain, touch, temprature detruser ms and lamina propria –strech receptor these afferent passes via inferior hypogastric plexus Then spinal micturition reflex comes in play controlled by higher centres.