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The Regulation of Gut Function and Motility Antonia Jameson Jordan, D.V.M., Ph.D.
Lecture outline: ,[object Object],[object Object],[object Object],[object Object]
GI functions: ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
input output
GI motor activity: ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Propulsion: ,[object Object]
Peristalsis: http://www.wzw.tum.de/humanbiology/data/motility/35/?alt=english
Mixing: ,[object Object],[object Object]
Segmenting contractions: http://www.wzw.tum.de/humanbiology/data/motility/35/?alt=english
Schematic of gastric emptying:
Gastric emptying: http://www.wzw.tum.de/humanbiology/motvid01/movie_04_1mot01.wmv
Control of gut motility: ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Intrinsic rhythmic contractility of GI smooth muscle: ,[object Object],[object Object],[object Object],[object Object]
Interstitial cells of Cajal (ICC) serve as pacemakers for GI muscles: Horowitz et al.   Annu. Rev. Physiol.  1999. 61: 19-43
Enteric nervous system: ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],http://www.udel.edu/biology/Wags/histopage/colorpage/cne/cnemap.GIF
Targets of enteric neurons: ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Extrinsic nervous regulation: ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Central Autonomic Neural Network Effector Systems (muscle, secretory epithelium, endocrine cells, vasculature) Enteric Nervous System (myenteric plexus, submucous plexus) Parasympathetic  Nervous System Intermediate cells Parasympathetic ganglia Sympathetic ganglia Nodose ganglia Dorsal-root ganglia Sympathetic  Nervous System Central Nervous System
GI reflexes: ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Peristaltic reflex: ,[object Object],[object Object],[object Object],[object Object],[object Object]
Gastrointestinal motility disorders: ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Congenital aganglionosis: ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Postoperative ileus in horses:
Postoperative ileus (POI) in horses: ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Pathophysiology of POI: ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Prevention and treatment of POI: ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Bugs Bunny: ,[object Object],[object Object],[object Object],[object Object],[object Object]
Physical exam: ,[object Object],[object Object],[object Object]
JAVMA, Vol 225, No. 5, September 1, 2004
Gastrointestinal stasis syndrome: ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Gastrointestinal stasis syndrome: ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Key points: ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Vomiting: http://www.wzw.tum.de/humanbiology/data/motility/35/?alt=english

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Gut motility lecture

Editor's Notes

  1. Your schedule says the title of this lecture is the regulation of gut function and motility, But I will be focusing on the gi motility this is in itself a huge topic so I will be thinking of it from the perspective of clinical relevance THIS IS NOT THE MOST Palatable subject in veterinary medicine, but it may be one of the most relevant. Motility disorders can result diarrhea, constipation, vomiting, heartburn.