Anthropology 130- Makeup Exam Two Please answer four (4) of the following questions. You may use any sources that you like, including your text book. Please take note: This exam is an opportunity to demonstrate how much you have learned about each topic, not a chance to answer each question as quickly and superficially as possible. Each of your answers must be a minimum of one page, double spaced, 12 point font. You should provide relevant examples to illustrate concepts or areas of knowledge, key dates, persons, discoveries, and key evidence or data that support a concept or conclusion. You have one week to complete this assignment. Please use a word-processor, including a file format compatible with Microsoft Word. Please return your exam to me by email. (1) In what ways have changes in the economy and technology of the United States during the 20th Century changed marriage, family and sexual practices, according to the Anthropologist Marvin Harris? (2) What are some of the most important trends in marriage, family and child-bearing in the U.S. since the 1950s? Why do you think these have come about? (3) In economic anthropology, what is the basis of the debate between the formalists and the substantivists? (4) To what extent do you think that an interest in the occult and supernaturalism exist in modern society? Give examples. (5) At one time, some Anthropologists predicted that magic and religion would disappear from our society, particularly as science and technology advanced. How, in your view, has this prediction worked out? Give examples. (6) What functions do kinship systems provide in non-industrial societies? (7) Describe types of marriage and post-marital residence patterns found in various societies. (8) To what extent would you say that rites of intensification are found within societies today? Give examples. 1 Dr. Tamma BMS 687, Molecular Immunology. Exam 2 An 8 month old boy who had several major bacterial and viral infections over the past 3 months was recently referred to an immunologist by his pediatrician. Diagnostic tests revealed that this patient has a SCID immunodeficiency disease and negligible numbers of both B and T lymphocytes. Analysis of DNA obtained from the child’s peripheral B cells revealed that both heavy chain alleles were in the following configuration: V1 V2 V3 V4 Vn D1 D2 D3 Dn J1 J2 J3 Jn 1. The above gene configuration is representative of: A. The germline heavy chain locus B. The gemline kappa light chain locus C. The rearranged heavy chain locus D. The rearranged kappa light chain locus E. The rearranged lambda light chain locus 2. Which of the following statements is most likely correct? A. The patient is unable to rearrange his heavy chain genes only B. The patient is unable to re.

1. Anthropology 130- Makeup Exam Two
Please answer four (4) of the following questions. You may use
any sources that you
like, including your text book. Please take note: This exam is
an opportunity to
demonstrate how much you have learned about each topic, not a
chance to answer
each question as quickly and superficially as possible. Each of
your answers must
be a minimum of one page, double spaced, 12 point font. You
should provide
relevant examples to illustrate concepts or areas of knowledge,
key dates, persons,
discoveries, and key evidence or data that support a concept or
conclusion. You have
one week to complete this assignment. Please use a word-
processor, including a file
format compatible with Microsoft Word. Please return your
exam to me by email.
(1) In what ways have changes in the economy and technology

2. of the United States
during the 20th Century changed marriage, family and sexual
practices, according to the
Anthropologist Marvin Harris?
(2) What are some of the most important trends in marriage,
family and child-bearing in
the U.S. since the 1950s? Why do you think these have come
about?
(3) In economic anthropology, what is the basis of the debate
between the formalists
and the substantivists?
(4) To what extent do you think that an interest in the occult
and supernaturalism exist
in modern society? Give examples.
(5) At one time, some Anthropologists predicted that magic and
religion would
disappear from our society, particularly as science and
technology advanced. How, in
your view, has this prediction worked out? Give examples.

3. (6) What functions do kinship systems provide in non-industrial
societies?
(7) Describe types of marriage and post-marital residence
patterns found in various
societies.
(8) To what extent would you say that rites of intensification
are found within societies
today? Give examples.
1
Dr. Tamma BMS 687, Molecular Immunology. Exam 2
An 8 month old boy who had several major bacterial and viral
infections over the past 3 months
was recently referred to an immunologist by his pediatrician.
Diagnostic tests revealed that this
patient has a SCID immunodeficiency disease and negligible
numbers of both B and T
lymphocytes. Analysis of DNA obtained from the child’s
peripheral B cells revealed that both

4. heavy chain alleles were in the following configuration:
V1 V2 V3 V4 Vn D1 D2 D3 Dn
J1 J2 J3 Jn
1. The above gene configuration is representative of:
A. The germline heavy chain locus
B. The gemline kappa light chain locus
C. The rearranged heavy chain locus
D. The rearranged kappa light chain locus
E. The rearranged lambda light chain locus
2. Which of the following statements is most likely correct?
A. The patient is unable to rearrange his heavy chain genes
only
B. The patient is unable to rearrange his T cell receptor genes
only

5. C. The patient is unable to rearrange his heavy and light chain
genes only
D. The patient is unable to rearrange his immunoglobulin and T
cell receptor genes
3. The likely cause of this immunodeficiency is the following:
A. Jak 3 kinase deficiency
B. Adenosine deaminase deficiency
C. RAG2 deficiency
D. Btk deficiency
E. IL2-R alpha chain deficiency
4. The BEST type of treatment for this patient would be:
A. Bone marrow transplantation
B. Intravenous gamma globulin (IVGG)
2

6. C. Antibiotics
D. Corticosteroids
E. Co-stimulatory blockade
Your patient, who is a 36 year old woman with lupus, has
recently been found to have elevated
levels of protein and traces of blood in her urine. You suspect
that she may be developing
nephritis caused by the deposition of IgG antibodies and
immune complexes in her kidney and
have requested a kidney biopsy.
5. What assay would best help you detect the presence of IgG
antibody in a tissue biopsy
obtained from her kidney?
A. ELISA
B. Immunofluorescence microscopy
C. Western blot
D. FACS analysis
E. Coombs test
6. Which one of the following properties of antibodies is NOT

7. dependent on the structure of the
heavy-chain constant region? What would be the best answer?
A. Ability to cross the placenta
B. Isotype (class)
C. Ability to fix complement
D. Ability to promote opsonization
E. Affinity for antigen
7. The germinal centers in the lymph nodes and spleen are the
major sites of the following
EXCEPT:
A. B and T cell activation
B. Isotype switching
C. Somatic mutation
D. Lymphocyte development
E. Plasma cell formation
8. The membrane IgM and IgD on the surface of an individual

8. B-cell
A. Have identical heavy chains but different light chains
B. Are identical except for their CH regions
C. Are identical except for their VH regions
D. Have different VH and VL regions
9. An individual who is heterozygous for the gamma heavy
chain allotype (Gm) contains two
allelic forms of IgG in serum, but individual lymphocytes
produce only one of the two forms.
3
This phenomenon, known as allelic exclusion is consistent with:
A. functional rearrangement of a heavy chain gene on only
chromosome in a B- cell
B. Functional rearrangements of heavy chain genes on both
chromosomes in a B- cell
C. Functional rearrangements of light chain genes on both
chromosomes in a B- cell
D. Alternative RNA splicing of immunoglobulin heavy chain
genes in different B-cells

9. 10. Chronic passive immunoglobulin administration is a
reasonable therapy for all of the
following immunodeficiency disorders EXCEPT:
A. Bruton's type hypogammaglobulinemia
B. Transient hypogammaglobulinemia of infancy
C. IgG deficiency with high IgM
D. Hypogammaglobulinemia
E. Selective IgA deficiency
11. John, a 14-month-old boy with severe gram-positive
bacterial pneumonia, is referred to the
Children's Hospital by the family physician. This is his third
such infection In 4 months. He has
two healthy sisters aged 3 and 5 years. The family lost a boy at
10 months of age to bacterial
pneumonia 6 years ago. The family doctor has sent along some
blood test results that show low
serum immunoglobulin levels (all classes), few B cells, but
normal numbers and functioning of T
cells. Which one of the following is the most likely diagnosis?

10. A. X-linked hypogammaglobulinemia
B. Common variable hypogammaglobulinemia
C. Transient hypogammaglobulinemia of infancy
D. CD40 genetic defect
E. Severe combined immunodeficiency
12. A 25-year-old woman went to see her physician
complaining of being tired and run down.
Because of her lack of energy, she had given up her regular
exercise program, a routine she had
maintained for a number of years. Until a year ago she had
been very active and considered
herself in excellent physical condition. However, in the last
year she had experienced several
protracted colds and three vaginal yeast infections, which had
not previously been a problem.
During the physical examination the physician noted that
several of her lymph nodes were
enlarged, yet no present infection was evident. She admits to
multiple sexual partners, and since
she uses birth control pills she never uses condoms. The general
practitioner ordered a series of

11. tests to measure her immune system. Her tests revealed a lower
than normal CD4+ T cell count.
What type of infection would manifest in this manner?
A. HIV infection
B. Any virus
C. Bacterial
D. Fungal
E. Parasitic
4
13. A young mother living in Africa is HIV positive and has
just given birth to a baby girl. As
her physician you are to advise her whether to breast feed her
infant. Because this is a region in
Africa where many children die of gastrointestinal infections,
you are in a dilemma as to what
to advise. Furthermore, you know that breast feeding has been
shown to be protective for the
infant. Breast feeding protects the infant from infections

12. because the mother's following are
passively acquired by the nursing infant.
A. IgA antibodies (secretory IgA)
B. IgM antibodies
C. IgE antibodies
D. Natural killer cells
E. Hemagglutinins
14. Joan is a 17-year-old girl who comes to your emergency
department in the terminal stages of
delivery. You determine this to be an uneventful pregnancy (she
is now 39 weeks of gestation).
She has had essentially no antenatal care. She delivered a
healthy baby boy, and the delivery
itself is uncomplicated. You order the nurse to give Joan an
injection of RhoGam. The rationale
for this is that you are concerned that the
A. Mother is Rh- and the baby is Rh+
B. Father is Rh+ and the baby is Rh-
C. Mother is Rh+ and the baby is Rh-

13. D. Father is Rh— and the baby is Rh+
E. Father and the baby are both Rh-, while the mother is Rh+
15. Jane, a 15-month-old infant, was brought to her family
practice clinic for her routine well-
child examination. During the course of the office visit, Jane
received her first measles
immunization. For successful immunization leading to
formation of specific memory cells, all
the following cell types would need to be activated EXCEPT
A. T cells
B. B cells
C. Dendritic cells
D. Eosinophils