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CELLULAR CYCLECELLULAR CYCLE
By: Juan José Garcés Ortiz
2015
Third semestre
Cell Cycle is a very
importan process in
which cell are able to
self- reproduce and
preserve their
genetic material
The Cell Cycle is
composed by 5
phases,
G1,S,G2,Mitosis and
G0
SMALL SIGNALING
MOLECULES GIVES GREEN
LIGHT FOR CELL DIVISION
Universität Basel.
(2015, May 7)
SMALL SIGNALING MOLECULESSMALL SIGNALING MOLECULES
GIVES GREEN LIGHT FOR CELLGIVES GREEN LIGHT FOR CELL
DIVISIONDIVISION
1. c-di-GMP controls the cell
cycle in a similar way as a
traffic light works. In the
absence of c-di-GMP in the
cell, the light shows red. This
indicates that the cell will have
to remain in the first phase of
the cell cycle.
SMALL SIGNALING MOLECULESSMALL SIGNALING MOLECULES
GIVES GREEN LIGHT FOR CELLGIVES GREEN LIGHT FOR CELL
DIVISIONDIVISION
If the c-di-GMP level
increases, the light
switches to green and
the cell enters the
next phase.
SMALL SIGNALING MOLECULESSMALL SIGNALING MOLECULES
GIVES GREEN LIGHT FOR CELLGIVES GREEN LIGHT FOR CELL
DIVISIONDIVISION
However, as soon as c-di-GMP is
produced, it binds to the enzyme,
thus altering its structure and mode
of action. Subsequently, this
blockade is lifted and the bacterial
chromosome can be copied.
SMALL SIGNALING MOLECULESSMALL SIGNALING MOLECULES
GIVES GREEN LIGHT FOR CELLGIVES GREEN LIGHT FOR CELL
DIVISIONDIVISION
Student opinion.Student opinion.
I think this is important
because, they are many thing
´s that are still a mystery,
regarding all this process ,
and discovering this new
molecules will help us reach
the goal of understanding
this whole process
How dividing cells end up the
same size.
Duke University
(June 4, 2015)
How dividing cells end up the sameHow dividing cells end up the same
sizesize
This finding goes against
recent publications
suggesting cells always
add the same amount of
mass, with some random
fluctuations, before
beginning division.
How dividing cells end up the sameHow dividing cells end up the same
sizesize
The team was looking at
how genes on circular
pieces of DNA called
plasmids segregate
when cells divide by
tagging the genes with
different fluorescent
colors.
How dividing cells end up the sameHow dividing cells end up the same
sizesize
The setup allows
researchers to watch
hundreds of cells go
through divisions
over dozens of
generations and was
key in seeing the
baffling oscillations.
How dividing cells end up the sameHow dividing cells end up the same
sizesize
Student Opinion
This investigation is
import because will help
us, in a better
understanding of the cell
reproductive system and
how mom cells, are a
main fact for future
studies.
MEDICAL UTILITYMEDICAL UTILITY
Medical UtilityMedical Utility
These studies represent a
good advance to reveal
new data, about the
process of cell
reproduction, that may
be used for future studies
of their main related
pathology, the cancer.
Medical UtilityMedical Utility
Discovering new
molecules that are
involved in the process
is very important
because, ass better we
know the mechanism ,
we will be able to repair
it and make it better.
Medical UtilityMedical Utility
Most of the cancer start
during the cell cycle, and the
oportunity to repair this is by
studying this process and
keep discovering new
information, that will lead us
to the cure.
BIBLIOGRAPHYBIBLIOGRAPHY
 Universität Basel. (2015, May 7). Small signaling molecule gives
green light for cell division. ScienceDaily. Retrieved July 26, 2015
from
www.sciencedaily.com/releases/2015/05/150507082437.htm
 Duke University. (2015, June 4). How dividing cells end up the
same size.ScienceDaily. Retrieved July 26, 2015 from
www.sciencedaily.com/releases/2015/06/150604141828.htm
 Martinez Sanchez, Lina Maria. Biologia Molecular.7.ed.Medellin:
UPB. Fac.Medicina.
Plegable biomol 2

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Plegable biomol 2

  • 1. CELLULAR CYCLECELLULAR CYCLE By: Juan José Garcés Ortiz 2015 Third semestre
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  • 4. Cell Cycle is a very importan process in which cell are able to self- reproduce and preserve their genetic material The Cell Cycle is composed by 5 phases, G1,S,G2,Mitosis and G0
  • 5. SMALL SIGNALING MOLECULES GIVES GREEN LIGHT FOR CELL DIVISION Universität Basel. (2015, May 7)
  • 6. SMALL SIGNALING MOLECULESSMALL SIGNALING MOLECULES GIVES GREEN LIGHT FOR CELLGIVES GREEN LIGHT FOR CELL DIVISIONDIVISION 1. c-di-GMP controls the cell cycle in a similar way as a traffic light works. In the absence of c-di-GMP in the cell, the light shows red. This indicates that the cell will have to remain in the first phase of the cell cycle.
  • 7. SMALL SIGNALING MOLECULESSMALL SIGNALING MOLECULES GIVES GREEN LIGHT FOR CELLGIVES GREEN LIGHT FOR CELL DIVISIONDIVISION If the c-di-GMP level increases, the light switches to green and the cell enters the next phase.
  • 8. SMALL SIGNALING MOLECULESSMALL SIGNALING MOLECULES GIVES GREEN LIGHT FOR CELLGIVES GREEN LIGHT FOR CELL DIVISIONDIVISION However, as soon as c-di-GMP is produced, it binds to the enzyme, thus altering its structure and mode of action. Subsequently, this blockade is lifted and the bacterial chromosome can be copied.
  • 9. SMALL SIGNALING MOLECULESSMALL SIGNALING MOLECULES GIVES GREEN LIGHT FOR CELLGIVES GREEN LIGHT FOR CELL DIVISIONDIVISION Student opinion.Student opinion. I think this is important because, they are many thing ´s that are still a mystery, regarding all this process , and discovering this new molecules will help us reach the goal of understanding this whole process
  • 10. How dividing cells end up the same size. Duke University (June 4, 2015)
  • 11. How dividing cells end up the sameHow dividing cells end up the same sizesize This finding goes against recent publications suggesting cells always add the same amount of mass, with some random fluctuations, before beginning division.
  • 12. How dividing cells end up the sameHow dividing cells end up the same sizesize The team was looking at how genes on circular pieces of DNA called plasmids segregate when cells divide by tagging the genes with different fluorescent colors.
  • 13. How dividing cells end up the sameHow dividing cells end up the same sizesize The setup allows researchers to watch hundreds of cells go through divisions over dozens of generations and was key in seeing the baffling oscillations.
  • 14. How dividing cells end up the sameHow dividing cells end up the same sizesize Student Opinion This investigation is import because will help us, in a better understanding of the cell reproductive system and how mom cells, are a main fact for future studies.
  • 16. Medical UtilityMedical Utility These studies represent a good advance to reveal new data, about the process of cell reproduction, that may be used for future studies of their main related pathology, the cancer.
  • 17. Medical UtilityMedical Utility Discovering new molecules that are involved in the process is very important because, ass better we know the mechanism , we will be able to repair it and make it better.
  • 18. Medical UtilityMedical Utility Most of the cancer start during the cell cycle, and the oportunity to repair this is by studying this process and keep discovering new information, that will lead us to the cure.
  • 19. BIBLIOGRAPHYBIBLIOGRAPHY  Universität Basel. (2015, May 7). Small signaling molecule gives green light for cell division. ScienceDaily. Retrieved July 26, 2015 from www.sciencedaily.com/releases/2015/05/150507082437.htm  Duke University. (2015, June 4). How dividing cells end up the same size.ScienceDaily. Retrieved July 26, 2015 from www.sciencedaily.com/releases/2015/06/150604141828.htm  Martinez Sanchez, Lina Maria. Biologia Molecular.7.ed.Medellin: UPB. Fac.Medicina.