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Impact of a Pandemic Triage Tool
                                                 on Intensive Care Admissions
                CANBERRA                                       A Bailey, I A Leditschke, J Ranse, K Grove
                H O S P I TA L
         A division of ACT Health                            Intensive	Care	Unit,	Canberra	Hospital,	Canberra,	Australia.


InTRoduCTIon
During	a	pandemic,	health	care	services	are	likely	to	become	quickly	overwhelmed.	                       Figure 2: Initial SOFA score assessment
Emergency	departments	will	need	to	triage	patients	on	presentation	to	ensure	that	the	
greatest good is achieved for the greatest number of patients. This triage principle also                 Traige code                     Criteria                                                           Action or priority
applies	to	other	hospital	services	that	may	experience	a	demand	for	their	services,	such	                                                                                                                    Highest	priority
as	the	intensive	care	unit	[ICU].	Recently	there	has	been	increased	interest	in	pandemic	                 Red                             SOFA score ≤7 or single-organ failure
preparedness	and	the	use	of	critical	care	resources	during	a	pandemic1.
                                                                                                          Yellow                          SOFA	score	8	–	11                                                  Intermediate	priority
Various	triage	tools	have	been	developed	to	assist	in	the	clinical	decision	making	of	ICU	
                                                                                                                                                                                                             ·Defer	or	discharge
resource	provision	for	critically	unwell	patients	during	a	pandemic2,3.	However,	to	date	                 GReen                           No significant organ faiure
                                                                                                                                                                                                             ·Reassess	as	needed
these	tools	have	not	been	applied	to	a	‘real’	patient	population.
                                                                                                                                                                                                             ·Manage	medically
                                                                                                          Blue                            Exlusion	criteria	met	or	SOFA	score	>11                            ·Provide	palliative	care	as	needed
                                                                                                                                                                                                             ·Discharge	from	critical	care
Figure 1: Inclusion / Exclusion criteria

     Inclusion criteria                           Exclusion Criteria
                                                                                                         Figure 3: 48-hour and 120- hour assessments
  A.	 Requirement	for	invasive	ventilatory	       A.	Severe	trauma
      support                                     B.	Severe	burns	of	patient	with	any	2	of	the	           Traige code                     Criteria                                                           Action or priority
       I.	 Refactory	hypoxemia	(SpO2		                 following:
             <	90%	on	non-rebreather	mask	             •	 Age	>	60	yr
                                                                                                          Red                             SOFA	score	<11	and	decreasing	                                     Highest	priority
             or	FiO2	>0.85)                            •	 >	40%	of	total	body	surface	area	
       II.	 Respiratory	acidosis	(pH	<	7.2)                 affected
       III.	 Clinical	evidence	of	impending	           •	 Inhalation	injury                               Yellow                          SOFA	score	stable	at	<8	with	no	change                             Intermediate	priority
             respiratory	failure	                 C.	Cardiac	arrest
       IV.	 Inability	to	protect	own	airway            •	 Unwitnessed	cardiac	arrest                      GReen                           No	longer	dependent	on	ventilator                                  ·Discharge	from	critical	care
                                                       •	 Witnessed	cardiac	arrest,	not	responsive	
  B.	 Hypotension	(systolic	blood	pressure	                 to electrical therapy (defibrillation or      Blue                            Exclusion	criteria	met	or	SOFA	score	>11	or	 ·Provide	palliative	care	as	needed
      <	90	mm	Hg	or	relative	hypotension)	                  pacing)                                       (48-houR)                       SOFA	score	stable	at	8-11	with	no	change ·Discharge	from	critical	care
      with	clinical	evidence	of	shock	(altered	        •	 Recurrent	cardiac	arrest
      level	of	consciousness,	decreased	          D.	Severe	baseline	cognitive	impairment                 Blue                            Exlusion	criteria	met	or	SOFA	score	>11	or	                        •	Provide	palliative	care	as	needed
      urine	output	or	other	evidence	of	end-      E.	Advanced	untreatable	neuromuscular	disease           (120-houR)                      SOFA	score	<8	with	no	change                                       •	Discharge	from	critical	care
      organ	failure)	refractory	to	volume	        F.	 Metastatic	malignant	disease
      resuscitation	requiring	vasopressor	        G.	Advanced	and	irreversible	
      or	inotrope	support	that	cannot	be	              immunocompromise
      managed	in	ward	setting                     H.	Severe	and	irreversible	neurological	event	or	
                                                       condition                                         Figure 4: Application of triage tool to ICU admissions
                                                  I.	 End-stage	organ	failure	meeting	the	following	
                                                       criteria:
                                                                                                             Total number of patients	
                                                       Heart
                                                       •	 NYHA	class	III	or	IV	heart	failure
                                                       Lungs
                                                       •	 COPD	with	FEV1	<	25%	predicted,	                   Meets	initial	inclusion	criteria
                                                            baseline	PaO2	<	55	mm	Hg,	or	
                                                            secondary	pulmonary	hypertension
                                                       • Cystic fibrosis with postbronchodilator             48	-hour	inclusion	criteria	re-assessment
                                                            FEV1	<	30%	or	baseline	PaO2	<	55	mm	
                                                            Hg
                                                       • Pulmonary fibrosis with VC or TLC
                                                            <	60%	predicted,	baseline	PaO2	<	                Meets	exclusion	criteria
                                                            55	mm	Hg,	or	secondary	pulmonary	
                                                            hypertension
                                                       •	 Primary	pulmonary	hypertension	with	               Initial	assessment
                                                            NYHA	class	III	or	IV	heart	failure,	right	
                                                            atrial	pressure	>	10	mm	Hg,	or	mean	
                                                            pulmonary	arterial	pressure	>	50	mm	Hg
                                                       Liver                                                 48-hour	assessment
                                                       • Child–Pugh score ≥ 7
                                                  J.	Age	>	85	yr
                                                  K.	Elective	palliative	surgery                             120-hour	assessment




MeThods                                                                                                  dIsCussIon
We	performed	a	retrospective	observational	study	of	the	application	of	the	pandemic	                     Use	of	this	triage	tool	creates	substantial	surge	capacity	when	applied	to	our	usual	
triage	tool	described	by	Christian	et	al2	[Fig.	1],	to	all	admissions	to	our	14	bed	general	             ICU patients. However, whether the tool will provide sufficient surge capacity in an
medical-surgical	ICU	over	a	4	week	period	in	February	2007.                                              actual	pandemic	is	untested.	Careful	management	of	community	expectations	may	be	
                                                                                                         required	to	implement	the	tool,	as	most	patients	currently	admitted	to	our	ICU	would	be	
                                                                                                         excluded.
ResulTs
                                                                                                         The tool aims to identify patients that will most benefit from admission to the ICU
119	patients	were	admitted	over	the	study	period	with	a	mean	age	of	60	years	(range	1-                   and	excludes	patients	considered	to	be	“too	well”,	“too	sick”	or	with	co-morbidities	
89) and a mean ± standard deviation APACHE II score of 14.88; ± of 7.95 (range 4-47).                    likely to limit survival in the shorter term2. The data we have presented generate
Figure	4	demonstrates	the	application	of	the	triage	tool	to	this	sample.                                 serious	questions	about	the	appropriateness	of	our	current	use	of	ICU	resources	and	
                                                                                                         are	consistent	with	the	health	care	spending	data	demonstrating	that	a	substantial	
On	admission	only	23.5%	(n=28)	met	the	triage	inclusion	criteria,	whilst	76.5%	(n=91)	                   proportion	of	health	care	resources	are	consumed	in	the	last	year	of	life4.
of these patients did not meet the triage inclusion criteria. The excluded patients were
reassessed	at	48	and	120	hours.	At	this	point	an	additional	1	patient	was	included.	                     Testing of the tool in other ICUs would be useful, as the data generated could be used
                                                                                                         to	facilitate	community	discussion	about	likely	differences	in	ICU	management	in	a	
The exclusion criterion was then applied to the included 24% (n=29) patients. Following                  pandemic situation and may also aid the identification and comparison of differences in
this, only 10% (n=12) patients from original 119 qualified for further application of the                resource	management	between	ICUs.
triage	tool.
                                                                                                         References
                                                                                                         1. Challen K, Bentley A, Bright J, Walter D. Clinical review: mass casualty triage-pandemic influenza and critical care. Critical Care 2007;11:212.
The remaining 10% had the sequential organ failure assessment [SOFA] score applied.                      2. Christian MD, Hawryluck L, Wax RS, et al. Development of a triage protocol for critical care during an influenza pandemic. CMAJ 2006;175:1377.
From	this,	1	of	the	12	patients	was	deemed	“too	sick”	and	recommended	for	palliation,	                   3. Talmor D, Jones A, Rubinson L, Howell MD, Shapiro NI. A simple triage scoring system predicting death and the need for critical care resources for use
                                                                                                            during epidemics. Crit Care Med 2007;35(5):1251-1256.
therefore	leaving	9.2%	(n=11)	patients	who	ICU	management	was	deemed	appropriate.                        4. Barnato A. End-of-life spending: can we rationalise costs? Critical Quarterly 2007; 49(3):84-92.

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Impact of a pandemic triage tool on intensive care admissions

  • 1. Impact of a Pandemic Triage Tool on Intensive Care Admissions CANBERRA A Bailey, I A Leditschke, J Ranse, K Grove H O S P I TA L A division of ACT Health Intensive Care Unit, Canberra Hospital, Canberra, Australia. InTRoduCTIon During a pandemic, health care services are likely to become quickly overwhelmed. Figure 2: Initial SOFA score assessment Emergency departments will need to triage patients on presentation to ensure that the greatest good is achieved for the greatest number of patients. This triage principle also Traige code Criteria Action or priority applies to other hospital services that may experience a demand for their services, such Highest priority as the intensive care unit [ICU]. Recently there has been increased interest in pandemic Red SOFA score ≤7 or single-organ failure preparedness and the use of critical care resources during a pandemic1. Yellow SOFA score 8 – 11 Intermediate priority Various triage tools have been developed to assist in the clinical decision making of ICU ·Defer or discharge resource provision for critically unwell patients during a pandemic2,3. However, to date GReen No significant organ faiure ·Reassess as needed these tools have not been applied to a ‘real’ patient population. ·Manage medically Blue Exlusion criteria met or SOFA score >11 ·Provide palliative care as needed ·Discharge from critical care Figure 1: Inclusion / Exclusion criteria Inclusion criteria Exclusion Criteria Figure 3: 48-hour and 120- hour assessments A. Requirement for invasive ventilatory A. Severe trauma support B. Severe burns of patient with any 2 of the Traige code Criteria Action or priority I. Refactory hypoxemia (SpO2 following: < 90% on non-rebreather mask • Age > 60 yr Red SOFA score <11 and decreasing Highest priority or FiO2 >0.85) • > 40% of total body surface area II. Respiratory acidosis (pH < 7.2) affected III. Clinical evidence of impending • Inhalation injury Yellow SOFA score stable at <8 with no change Intermediate priority respiratory failure C. Cardiac arrest IV. Inability to protect own airway • Unwitnessed cardiac arrest GReen No longer dependent on ventilator ·Discharge from critical care • Witnessed cardiac arrest, not responsive B. Hypotension (systolic blood pressure to electrical therapy (defibrillation or Blue Exclusion criteria met or SOFA score >11 or ·Provide palliative care as needed < 90 mm Hg or relative hypotension) pacing) (48-houR) SOFA score stable at 8-11 with no change ·Discharge from critical care with clinical evidence of shock (altered • Recurrent cardiac arrest level of consciousness, decreased D. Severe baseline cognitive impairment Blue Exlusion criteria met or SOFA score >11 or • Provide palliative care as needed urine output or other evidence of end- E. Advanced untreatable neuromuscular disease (120-houR) SOFA score <8 with no change • Discharge from critical care organ failure) refractory to volume F. Metastatic malignant disease resuscitation requiring vasopressor G. Advanced and irreversible or inotrope support that cannot be immunocompromise managed in ward setting H. Severe and irreversible neurological event or condition Figure 4: Application of triage tool to ICU admissions I. End-stage organ failure meeting the following criteria: Total number of patients Heart • NYHA class III or IV heart failure Lungs • COPD with FEV1 < 25% predicted, Meets initial inclusion criteria baseline PaO2 < 55 mm Hg, or secondary pulmonary hypertension • Cystic fibrosis with postbronchodilator 48 -hour inclusion criteria re-assessment FEV1 < 30% or baseline PaO2 < 55 mm Hg • Pulmonary fibrosis with VC or TLC < 60% predicted, baseline PaO2 < Meets exclusion criteria 55 mm Hg, or secondary pulmonary hypertension • Primary pulmonary hypertension with Initial assessment NYHA class III or IV heart failure, right atrial pressure > 10 mm Hg, or mean pulmonary arterial pressure > 50 mm Hg Liver 48-hour assessment • Child–Pugh score ≥ 7 J. Age > 85 yr K. Elective palliative surgery 120-hour assessment MeThods dIsCussIon We performed a retrospective observational study of the application of the pandemic Use of this triage tool creates substantial surge capacity when applied to our usual triage tool described by Christian et al2 [Fig. 1], to all admissions to our 14 bed general ICU patients. However, whether the tool will provide sufficient surge capacity in an medical-surgical ICU over a 4 week period in February 2007. actual pandemic is untested. Careful management of community expectations may be required to implement the tool, as most patients currently admitted to our ICU would be excluded. ResulTs The tool aims to identify patients that will most benefit from admission to the ICU 119 patients were admitted over the study period with a mean age of 60 years (range 1- and excludes patients considered to be “too well”, “too sick” or with co-morbidities 89) and a mean ± standard deviation APACHE II score of 14.88; ± of 7.95 (range 4-47). likely to limit survival in the shorter term2. The data we have presented generate Figure 4 demonstrates the application of the triage tool to this sample. serious questions about the appropriateness of our current use of ICU resources and are consistent with the health care spending data demonstrating that a substantial On admission only 23.5% (n=28) met the triage inclusion criteria, whilst 76.5% (n=91) proportion of health care resources are consumed in the last year of life4. of these patients did not meet the triage inclusion criteria. The excluded patients were reassessed at 48 and 120 hours. At this point an additional 1 patient was included. Testing of the tool in other ICUs would be useful, as the data generated could be used to facilitate community discussion about likely differences in ICU management in a The exclusion criterion was then applied to the included 24% (n=29) patients. Following pandemic situation and may also aid the identification and comparison of differences in this, only 10% (n=12) patients from original 119 qualified for further application of the resource management between ICUs. triage tool. References 1. Challen K, Bentley A, Bright J, Walter D. Clinical review: mass casualty triage-pandemic influenza and critical care. Critical Care 2007;11:212. The remaining 10% had the sequential organ failure assessment [SOFA] score applied. 2. Christian MD, Hawryluck L, Wax RS, et al. Development of a triage protocol for critical care during an influenza pandemic. CMAJ 2006;175:1377. From this, 1 of the 12 patients was deemed “too sick” and recommended for palliation, 3. Talmor D, Jones A, Rubinson L, Howell MD, Shapiro NI. A simple triage scoring system predicting death and the need for critical care resources for use during epidemics. Crit Care Med 2007;35(5):1251-1256. therefore leaving 9.2% (n=11) patients who ICU management was deemed appropriate. 4. Barnato A. End-of-life spending: can we rationalise costs? Critical Quarterly 2007; 49(3):84-92.