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Medicinens verden
Hvor biologien møder kemien
Anders og Jannick
“As far as the law is concerned, the dividing line is defined
in black and white
“As far as the party going teenager is concerned the law is
an ass”
Lægemidler vs. Narkotika
Hvad er kemi?
Hvad er kemi?
Hvad er biologi?
Blodtryk
Astma
Hovedpine
Hvad er biokemi?
Biologisk effekt
Medicin
Celle
Eksempel: Morfin
Morfins kemi
Morfins biologi og biokemi
Morfin
Isoleret i 1804
Diamorfin
Syntetiseret i 1874
Optimeret morfin
Øget optagelse i tarm
Øget smertestillende effekt
Øget optagelse i hjernen
= Heroin
Diamorfin
Kodein
Isoleret i 1832
Morfin
Isoleret i 1804
Heroin
Syntetiseret i 1874
Kodein
Gode og dårlige “drugs”?
Lægemiddel -> Krop
Lægemiddel -> Krop
krop
lægemiddel
Indtagelse
Udskillelse
Lægemiddel  Blodet
Kroppen -> Lægemiddel
Indtagelse
Tarm: Optagelse
Blod: Fordeling i kroppen
Effekt = Koncentration
Injektion  Blod
Udskillelse
Lever:
Enzymer
Nedbrydning
Nyrer:
Filtration
Udskillelse i urin
Medicin i kroppen
Indtagelse
Optagelse
Binding
Effekt
Nedbrydning
Udskillelse
Medicinens vej
Opdagelse
Udvikling
og
optimering
Afprøvning
i dyr
Afprøvning
i
mennesker
Lancering
Folkeskole
Gymnasium
Københavns
Universitet
Danmarks
Tekniske
Universitet
(DTU)
Forskning og produktion af medicin

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Drugs at Randersgadeskole d. 27.09.2013

Editor's Notes

  1. Anders
  2. JannickIntroduktionog catcher om “Drugs”/LægemidlervsNakotikaGodelægemidlerharvelingenbivirkningerogernemme at indtage. Skerdetaltid/nogensinde?Haralledårligelægemidler (narkotika) udelukkendedårligevirkninger.Vi måforstånogetgrundlæggendeførst.
  3. JannickHistorieoomuni-bogHeleverdeneropbyggetafkemi – ALT! AtomareniveauMegetaf den kemi vi kender, skerved at vi selvkansammensættegrundstoffertilnyestoffer med en gavnligvirkning.
  4. JannickLægemidlererogsåeksemplerpåkemi, her detaktivestof I to kendtelægemidler (morfineogparacetamol, “acetaminophene”)Detteersammensætningenafganskefågrundstoffer, en del Karbonatomer, oxygen atomer, hydrogen atomerog nitrogen atomer. Netopdisseer de mestbenyttede I den kemi vi kalderorganiskkemi, altsålevendekemi. Forklarstreg-formel KORT!
  5. Anders
  6. Anders
  7. Anders
  8. Jannick
  9. Anders
  10. Jannick
  11. AndersAfhængigaf den effektlægemidlethar I hjernen. Utilsigtet
  12. Anders – Jannick???Fængsel vs. 7-eleven
  13. JannickI harmåskebemærket at morphine og heroine beggebådehardårligeoggodeegenskaber, afhægigtafhvilken situation man befinder sig i. Der findes mange eksempler (Amphetamine, sukker etc.)Vi kanderforikke sort/hvidtinddelekemiskemolekyler I godeogdårlige. Detkommer an påomstændighederneogstoffetseffekt, varrighedog mange andre ting. (dødeligsmertevs heroin)Barbiturates blevgivettilsåredeved Pearl Harbor, men da man ikkekendetilhvordan de blevopbevarede I kroppen, døede mange af en overdosis. Faktiskanslåsdet at fleredøedeafoverdosis end afderessår.
  14. Jannick- Hvordanlægemidlerharindvirkningerpåvoreskropoghvordan de såskaberdenneeffekt
  15. Jannick
  16. Anders
  17. Anders
  18. Anders
  19. AndersBivirkninger! - Viagra
  20. Anders – Jannick???
  21. Anders