Floyd Mayweather has been accused of a doping violation prior to his May 2015 fight against Manny Pacquiao, where he defeated Pacquiao and improved his record to 48-0. USADA collection agents discovered Mayweather had received an IV the night before the fight for rehydration purposes, which contained substances that were banned when administered intravenously. Mayweather denied the allegations and said he did not commit any doping violations, claiming he was supported by USADA and did not violate any drug testing guidelines.