Dr. Folkman pioneered the field of angiogenesis, the formation of new blood vessels, which was important for understanding tumor growth. He worked at Harvard Medical School as a professor and identified key factors like VEGF that regulate angiogenesis. A metronomic regime uses low doses of drugs frequently to disrupt angiogenesis. Dr. Folkman was not able to cure cancer in two years as predicted, but is known for establishing angiogenesis research, though other drugs like Avastin and Sutent were developed after his work.