Herbal

1. By :
T.Chrestella Meryl 11.70.0020
Yuni Rusiana 11.70.0055
Yoceline Natania 11.70.0036
Jonathan Ali 11.70.0107
Febby Ernita S 11.70.0054
Tjan, Ivana 12.70.0057
Nora Csillag

2.  Introduction
 Bioactive Compounds & Functions
 Application

3.  Ciplukan flower /cut leaf Ground cherry
(Physalis angulata L.) is an annual herbaceous
plant which grows in low-land.
 It’s stems can grow up to 1-2 m in height and
the flower has bell-like form with yellow
colour.

4. The classification of Ciplukan flower
 Kingdom : Plantae
 Division : Spermatophyta
 Class : Dicotyledonnae
 Ordo : Solanales
 Family : Solanaceae
 Genus : Physalis
 Species : P. angulata L

5.  Leaves : physalin B, D, E, F, G, H, I, and K.
 Root, leaves, flower : saponin, with angulatin
A and flavonol glycoside (example : myrcetin
neohesperidoside, pigrin as alcaloid
compound)
 Fatty acid : palmitic and stearate acid
 Fruits : 24,5 mg of vitaminC, 6% of sugar, and
7% of protein in 100 ml of juice and rich in
cryophytoxanthin
 Terpenes, flavonoid and citric acid.

6. 1. Saponins and alkaloid : bitter taste, efficacious
as anti tumor and prevented cancer growth,
especially colon cancer whereas flavonoids
acted as antioxidant
2. Physalin : prevent the growth of some cancer
cells, whereas B physalin was cytotoxic to some
of cancer cell and leukemia cancer cells.
3. Etanolic : cytotoxic effect and trigger the
apoptosis in breast cancer.

7. 4.Antidiabetic : leaf extract with 20% and 40% had the
effect of decreasing glucose concentration on mencit.
5. Myrcetin neohesperidoside : strong cytotoxicity
against the three tested cell lines.The strongest
action being observed with lymphocytic leukemia P-
388 cells
6. Antimicrobial : physalin-containing fractions were
effective in against Staphylococcus aureus,
Staphylococcus epidermidis, Pseudomonas aeruginosa,
Mycobacterium tuberculosis, Mycobacterium avium,
Mycobacterium kansasii, Mycobacterium malmoense
and Mycobacyterium intracellulare

8. 7. Antiinflammatory : 5 mg/kg extract of
Physalis angulata L.  effective effects to
treat the acute and chronic skin inflammatory
conditions
not recommended to eat immature ciplukan
flower because it had a toxic effect like the
other family of solanacea.

9. 1. Traditional medicine
 Laxative
 Drugulcers
 bleeding gums
 Sprains
 Stomachache
 Gonorrhea
 Diabetes
 Epilepsy
 Inflammation
 throat infections
 Diuretic
 analgesic (pain relieving)
 neutralizing toxins
 activating the body's glandular functions.

10. 2. Food Application
A.TEA
made from leaves and stem of
ciplukan which if consumed three times
a day can help to cure influenza,
whooping cough, bronchitis, and paroritis
B.TRADITIONAL BEVERAGE
boil the ciplukan plant such as
leaves, root, flower or
stem with water for some minutes.
C. SALAD  eaten raw
D. DESSERT
E. FLAVORING
F. FRUIT PRESERVES/ DRIED
G. PIE FILLING  contain pectin

11.  http://kaskushootthreads.blogspot.com/2014/07/ciplukan-tanaman-beribu-manfaat yang.html. Accesed on October 1st, 2014.
 BPOM RI. (2007). Acuan Sediaan Herbal, Ed. I. Vol. 3. BPOM RI. Jakarta.
 Fitria M., Armandari I., Septhea D.B., Hermawan A., Ikawati M., Meiyanto E. (2009). Ekstrak Etanolik Herba Ciplukan (Physalis Angulata L)
Berefek Sitotoksik dan Menginduksi Apoptosis Pada Sel Kanker Payudara MCF-7. Cancer Chemoprevention Research 1-10.
 Hall D.W., Vandiver V.V., Sellers B.A. (1991). Cutleaf Ground-cherry, Physalis angulata L. Florida, USA: University of Florida.
 Ismail N., Alam M. (2001). A Novel Cytotoxic Flavonoid Glycoside From Physalis angulata. J. Fitoterapia 72 : 676-679.
 Kemenkes RI. (2011). Formularium Obat Herbal Asli Indonesia Vol 1. DIPA Satuan Kerja Direktora Bina Pelayanan Kesehatan Tradisional,
Alternatif dan Komplementer. Jakarta.
 Pietro R.C.L.R., Kashima S., Sato D.N., Januario A.H., Franca C. (2000). In Vitro Antimycobacterial Activites of Physalis angulata L.
Phytomedicine Vol 7(4) : 335-338.
 Pinto N.B., Morais T.C., Carvalho K.M.B., Silva C.R., Andrade G.M., Brito G.A.C., Veras M.L., Pessoa O.D.L., Rao V.S., Santos F.A. (2010).
Topical Anti-Inflammatory Potential Of Physalin E From Physalis Angulata On Experimental Dermatitis in Mice. J. Phytomedicine 17 : 740-
743.
 Purnamasari, A. (2012). Ceplukan (Physalis minima L.). Universitas Indonesia.
 Sediarso, Sunaryo H., Amalia N. (2008). Efek Antidiabetes Dan Identifikasi Senyawa Dominan Dalam Fraksi Kloroform Herba Ciplukan
(Physalis angulata L.). J. Farmasi Indonesia 4(2) :63-69.
 Suijatmo A.B., Sukandar E.Y., Ratnawati Y., Kusmaningati S., Wulandari A., Narvikasari S. (2011). Efek Antidiabetes Herba Ciplukan
(Physalis Angulata LINN) Pada Mencit Diabetes Dengan Induksi Aloksan. J. Farmasi Indonesia 5(4) : 166-171.
 Yulianto, D. (2009). Inhibisi Xantin Oksidase Secara In Vitro oleh Ekstrak Rosela (Hibiscus sabdariffa) dan Ciplukan (Physalis angulata).
Institut Pertanian Bogor. Bogor.