Heart Cancer Symptoms and Signs Are The First Signal For The Doctors To Get The Symptoms Of Heart Cancer. Find out what common symptoms of heart cancer and serious symptoms of this cancer in the best website reviews about that. You mut to make sure when this cancer worsens it will show other Heart cancer symptoms and signs. The first serious symptom of this cancer changes in the level of consciousness or awareness. This is also followed by a change in mental status or sudden behavior change. More severe symptoms of the disease include heart palpitations, not producing any urine, paralysis or inability to move. In the last symptom may occur when cancer has affected other organs in the body. This means that cancer cells have taken the system.