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                                 Public                                                                                                        EMR
                                Databases
                                                                                                         Physician
                                                Patient
                                                                                                                                                      HIE
                                                                   Point of Care

                                                                                                                                                       Labs



                                                                      Real Time &
                                                                                                                                                   Imaging
                                                                      Secure Data
                                            iBlueButton                 Sharing
                                             Patient App
                                                                                               iBlueButton Professional                          Rx
                                                                                                    Physician App



                       The iBlueButton apps are based on Humetrix U.S. patent #5,995,965 and other pending patents. “Blue Button”, the Blue Button logo, and the
slogan “Download My Data” are registered Service Marks of the U.S. Department of Veterans Affairs (VA), an agency of the United States Government and are used by
               permission of VA. ©2012 Humetrix. The iBlueButton apps are based on Humetrix U.S. patent #5,995,965 and other pending patents.
iBlueButton® : Medicare Blue Button® Data Mash Up with
                 8 Different Federal Government Data Sources
1. v29 ICD-9-CM code (15,000 Diagnosis Codes; 3,900 Procedure Codes)
    The ICD-9-CM Coordination and Maintenance Committee includes Centers for Medicare and Medicaid Services (CMS), the Centers for
    Disease Control and Prevention (CDC) and the National Center for Health Statistics (NCHS)
                                                               https://www.cms.gov/Medicare/Coding/ICD9ProviderDiagnosticCodes/codes.html

2. FDA National Drug Code Directory (55,000 NDC codes)
    The FDA processes electronic submission of registration and listing information and stores the data using eLIST FDA software system
    and published weekly updates of the NDC numbers
                                                                                  http://www.fda.gov/Drugs/InformationOnDrugs/ucm142438.htm

3. CMS NPI registry (NPPES) (3.7 million NPI codes)
    The Centers for Medicare & Medicaid Services (CMS) has developed the National Plan and Provider Enumeration System (NPPES)
            http://www.cms.gov/Regulations-and-Guidance/HIPAA-Administrative-Simplification/NationalProvIdentStand/DataDissemination.html

4. National Library of Medicine RxNorm (17,000 distinct RxCUI concepts)
    A tool for supporting semantic interoperation between drug terminologies and pharmacy knowledge base systems produced and
    maintained by the National Library of Medicine
                                                                           http://www.nlm.nih.gov/research/umls/rxnorm/docs/rxnormfiles.html

5. NIH/National Library of Medicine Medline Plus Connect (1,200 Drug Information Records)
    MedlinePlus Connect provides AHFS Consumer Medication Information written especially for patients

                                                                                    http://www.nlm.nih.gov/medlineplus/connect/technical.html

6. Department of Veterans Affairs National Drug File-Reference Terminology (46,000 NUI Concepts)
    The NDF-RT™ Interagency Expert Panel (NDF-RT™ IEP), an on-going collaboration among the Department of Veterans Affairs (VA),
    Food and Drug Administration (FDA), National Library of Medicine (NLM), National Cancer Institute (NCI), Centers for Medicare
    and Medicaid Services (CMS)

                                                                                                     http://rxnav.nlm.nih.gov/NdfrtRestAPI.html
7. CMS UB04 and … 8. HCPCS codes (10,000 codes)
                                     http://www.cms.gov/Medicare/Coding/HCPCSReleaseCodeSets/index.html?redirect=/HCPCSReleaseCodeSets/
User-friendly Patient & Provider Display of Parsed,
Decoded & Mashed Up Medicare Blue Button® Record
    For Safer & More Cost-Effective Health Care

                                       iBlueButton Professional App




 iBlueButton Patient App




                           Real Time Parsing of Medicare Blue Button Text File &
                           Contextual Data Mash Up On Board the iBlueButton Apps,
                           with real-time translation of coded data, medication
                           reconciliation, and drug information & side effect look up
iBlueButton® Satisfies “The Three-Part Aim” of Better
 Health Care, Better Personal Health, and Lower Costs
1. Better Care Interactions with the Healthcare System:
    - In providing an up to date comprehensive medical history & current
    medication list for patients & their physicians to easily share at the POC
    - With patient immediate & easy access to contextual information
    about their medications & the ability to easily & directly share at the POC
    reported side effects and a reconciled drug list with their physicians
    - Eliminates language barriers therefore helping minorities to better care
2. Better Health for Oneself:
    - In providing patients a mobile tool (smart phone or tablet app) for use anytime
   and anywhere to easily download, view and share with their caregivers their medical
   history to better manage their personal health and healthcare
   - Reminding them of Medicare covered preventives services including the Annual
   Wellness Visit
3. Lower Costs:
    - Avoiding unnecessary hospital admissions and readmissions because of
   poly-pharmacy and other drug related adverse events with the provision at every POC
   of a current and reconciled drug list

                                                                                    4
Commercialization Plan
•   Humetrix has a 15-year history developing and commercializing software & technology solutions.

•   Our iBlueButton® system and apps have been available on iTunes since early 2012, and we have provided
    regular and material updates to the feature set of the apps. iTunes is the largest app store in the world and has
    streamlined app distribution, making it easy to get the apps into the hands of millions of Americans.

•   We have a seasoned and committed executive, development & support team; the IT & communications
    infrastructure required; and additionally are well capitalized to support the broad adoption of the iBlueButton
    apps.

•   We already have a published support plan in place, including both telephone and email support for the
    apps. We have many years of experience in ramping up customer-support divisions with Level 1, 2 and 3
    support tiers, along with industry-accepted escalation procedures.

•   We are in serious discussion with major players in the Federal Government and the Commercial Sector for
    deployment of the apps by State HIEs, large health plans, TRICARE, telecom companies; we are one of only
    three VA Blue Button health partners with our iBlueButton apps offered for use by Veterans since January,
    2012; we have been invited to present our apps by CMS and the OPM; we are in discussions with major ACOs
    and Medical Home Players to embed the iBlueButton technology into their new business models.

•   As one of the recently-announced, chosen semi-finalists of the Patient-Engagement Blue-Button Challenge, we
    will start on 9/10 a two-week trial with the Advisory Board Company and the Virginia Hospital Center.

•   In all, our pipeline has over 150M users right now.

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iBlueButton® Mashup of 8 Federal Health Data Sources

  • 1. 8 Public EMR Databases Physician Patient HIE Point of Care Labs Real Time & Imaging Secure Data iBlueButton Sharing Patient App iBlueButton Professional Rx Physician App The iBlueButton apps are based on Humetrix U.S. patent #5,995,965 and other pending patents. “Blue Button”, the Blue Button logo, and the slogan “Download My Data” are registered Service Marks of the U.S. Department of Veterans Affairs (VA), an agency of the United States Government and are used by permission of VA. ©2012 Humetrix. The iBlueButton apps are based on Humetrix U.S. patent #5,995,965 and other pending patents.
  • 2. iBlueButton® : Medicare Blue Button® Data Mash Up with 8 Different Federal Government Data Sources 1. v29 ICD-9-CM code (15,000 Diagnosis Codes; 3,900 Procedure Codes) The ICD-9-CM Coordination and Maintenance Committee includes Centers for Medicare and Medicaid Services (CMS), the Centers for Disease Control and Prevention (CDC) and the National Center for Health Statistics (NCHS) https://www.cms.gov/Medicare/Coding/ICD9ProviderDiagnosticCodes/codes.html 2. FDA National Drug Code Directory (55,000 NDC codes) The FDA processes electronic submission of registration and listing information and stores the data using eLIST FDA software system and published weekly updates of the NDC numbers http://www.fda.gov/Drugs/InformationOnDrugs/ucm142438.htm 3. CMS NPI registry (NPPES) (3.7 million NPI codes) The Centers for Medicare & Medicaid Services (CMS) has developed the National Plan and Provider Enumeration System (NPPES) http://www.cms.gov/Regulations-and-Guidance/HIPAA-Administrative-Simplification/NationalProvIdentStand/DataDissemination.html 4. National Library of Medicine RxNorm (17,000 distinct RxCUI concepts) A tool for supporting semantic interoperation between drug terminologies and pharmacy knowledge base systems produced and maintained by the National Library of Medicine http://www.nlm.nih.gov/research/umls/rxnorm/docs/rxnormfiles.html 5. NIH/National Library of Medicine Medline Plus Connect (1,200 Drug Information Records) MedlinePlus Connect provides AHFS Consumer Medication Information written especially for patients http://www.nlm.nih.gov/medlineplus/connect/technical.html 6. Department of Veterans Affairs National Drug File-Reference Terminology (46,000 NUI Concepts) The NDF-RT™ Interagency Expert Panel (NDF-RT™ IEP), an on-going collaboration among the Department of Veterans Affairs (VA), Food and Drug Administration (FDA), National Library of Medicine (NLM), National Cancer Institute (NCI), Centers for Medicare and Medicaid Services (CMS) http://rxnav.nlm.nih.gov/NdfrtRestAPI.html 7. CMS UB04 and … 8. HCPCS codes (10,000 codes) http://www.cms.gov/Medicare/Coding/HCPCSReleaseCodeSets/index.html?redirect=/HCPCSReleaseCodeSets/
  • 3. User-friendly Patient & Provider Display of Parsed, Decoded & Mashed Up Medicare Blue Button® Record For Safer & More Cost-Effective Health Care iBlueButton Professional App iBlueButton Patient App Real Time Parsing of Medicare Blue Button Text File & Contextual Data Mash Up On Board the iBlueButton Apps, with real-time translation of coded data, medication reconciliation, and drug information & side effect look up
  • 4. iBlueButton® Satisfies “The Three-Part Aim” of Better Health Care, Better Personal Health, and Lower Costs 1. Better Care Interactions with the Healthcare System: - In providing an up to date comprehensive medical history & current medication list for patients & their physicians to easily share at the POC - With patient immediate & easy access to contextual information about their medications & the ability to easily & directly share at the POC reported side effects and a reconciled drug list with their physicians - Eliminates language barriers therefore helping minorities to better care 2. Better Health for Oneself: - In providing patients a mobile tool (smart phone or tablet app) for use anytime and anywhere to easily download, view and share with their caregivers their medical history to better manage their personal health and healthcare - Reminding them of Medicare covered preventives services including the Annual Wellness Visit 3. Lower Costs: - Avoiding unnecessary hospital admissions and readmissions because of poly-pharmacy and other drug related adverse events with the provision at every POC of a current and reconciled drug list 4
  • 5. Commercialization Plan • Humetrix has a 15-year history developing and commercializing software & technology solutions. • Our iBlueButton® system and apps have been available on iTunes since early 2012, and we have provided regular and material updates to the feature set of the apps. iTunes is the largest app store in the world and has streamlined app distribution, making it easy to get the apps into the hands of millions of Americans. • We have a seasoned and committed executive, development & support team; the IT & communications infrastructure required; and additionally are well capitalized to support the broad adoption of the iBlueButton apps. • We already have a published support plan in place, including both telephone and email support for the apps. We have many years of experience in ramping up customer-support divisions with Level 1, 2 and 3 support tiers, along with industry-accepted escalation procedures. • We are in serious discussion with major players in the Federal Government and the Commercial Sector for deployment of the apps by State HIEs, large health plans, TRICARE, telecom companies; we are one of only three VA Blue Button health partners with our iBlueButton apps offered for use by Veterans since January, 2012; we have been invited to present our apps by CMS and the OPM; we are in discussions with major ACOs and Medical Home Players to embed the iBlueButton technology into their new business models. • As one of the recently-announced, chosen semi-finalists of the Patient-Engagement Blue-Button Challenge, we will start on 9/10 a two-week trial with the Advisory Board Company and the Virginia Hospital Center. • In all, our pipeline has over 150M users right now.