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Lee Saby is one of the most prestigious running technique coaches, having helped famous barefoot advocates such as Mc Dougall or Liebermann.
Proprioception making sense of barefoot running by lee saxby
Proprioception making sense of barefoot running by lee saxby
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RSV is an important cause of lower respiratory tract infections in children, the elderly and in those with underlying medical conditions. Although the high disease burden indicates an urgent need for a vaccine against RSV, no licensed RSV vaccine is currently available. We developed an RSV vaccine candidate based on the low-seroprevalent human adenovirus serotypes 26 and 35 (Ad26 and Ad35) encoding the RSV fusion (F) gene. Single immunization of mice with either one of these vectors induced high titers of RSV neutralizing antibodies and high levels of F specific interferon-gamma-producing T cells. A Th1-type immune response was indicated by a high IgG2a/IgG1 ratio of RSV-specific antibodies, strong induction of RSV-specific interferon-gamma and tumor necrosis factor-alpha cytokine producing CD8 Tcells, and low RSV-specific CD4 T-cell induction. Both humoral and cellular responses were increased upon a boost with RSV-F expressing heterologous adenovirus vector (Ad35 boost after Ad26 prime or vice versa). Both single immunization and prime-boost immunization of cotton rats induced high and long-lasting RSV neutralizing antibody titers and protective immunity against lung and nasal RSV A2 virus load up to at least 30 weeks after immunization. Cotton rats were also completely protected against challenge with a RSV B strain (B15/97) after heterologous prime-boost immunization. Lungs from vaccinated animals showed minimal damage or inflammatory infiltrates post-challenge, in contrast to animals vaccinated with formalin-inactivated virus. Our results suggest that recombinant human adenoviral Ad26 and Ad35 vectors encoding the RSV F gene have the potential to provide broad and durable protection against RSV in humans, and appear safe to be investigated in infants.
Recombinant low-seroprevalent adenoviral vectors Ad26 and Ad35
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A microporous covalent triazine polymer (CTP) network with a high surface area was synthesized via the Friedel-Crafts reaction for anticancer drug delivery and controlled release. The CTP is transformed to the nanoscale region by intense ultasonication followed by filtration to yield nanoscale CTP (NCTP) with excellent dispersibility in physiological solution while maintaining its chemical structure and the porosity of the material. An anti-cancer drug, doxorubicin (DOX), is loaded onto the NCTP through simple physisorption by hydrophobic and π–π interactions, and its release can be controlled at acidic and neutral pH. The NCTP did not show practical toxicity to cancer and normal cells, but the NCTP-DOX complex showed high efficacy at killing both types of cells in-vitro. The prolonged drug release (over 50h) from the NCTP-DOX at neutral and acidic pH values was demonstrated. The in-vitro cell imaging results indicate that NCTP has good potential for bio-imaging. The cellular senescence and potency of NCTP was confirmed by the expression of senescence associated marker proteins p53 and p21. These results suggest that NCTP can be used as a new platform for imaging and drug delivery, which may find potential applications in diagnosis and therapy.
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Lee Saby is one of the most prestigious running technique coaches, having helped famous barefoot advocates such as Mc Dougall or Liebermann.
Proprioception making sense of barefoot running by lee saxby
Proprioception making sense of barefoot running by lee saxby
Mayayo Oxigeno
Graphene based magnetic particle
Optimization of graphine fe3o4
Optimization of graphine fe3o4
Arun kumar
Collagen based material for tissue engineering work
Presen tisse
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Arun kumar
RSV is an important cause of lower respiratory tract infections in children, the elderly and in those with underlying medical conditions. Although the high disease burden indicates an urgent need for a vaccine against RSV, no licensed RSV vaccine is currently available. We developed an RSV vaccine candidate based on the low-seroprevalent human adenovirus serotypes 26 and 35 (Ad26 and Ad35) encoding the RSV fusion (F) gene. Single immunization of mice with either one of these vectors induced high titers of RSV neutralizing antibodies and high levels of F specific interferon-gamma-producing T cells. A Th1-type immune response was indicated by a high IgG2a/IgG1 ratio of RSV-specific antibodies, strong induction of RSV-specific interferon-gamma and tumor necrosis factor-alpha cytokine producing CD8 Tcells, and low RSV-specific CD4 T-cell induction. Both humoral and cellular responses were increased upon a boost with RSV-F expressing heterologous adenovirus vector (Ad35 boost after Ad26 prime or vice versa). Both single immunization and prime-boost immunization of cotton rats induced high and long-lasting RSV neutralizing antibody titers and protective immunity against lung and nasal RSV A2 virus load up to at least 30 weeks after immunization. Cotton rats were also completely protected against challenge with a RSV B strain (B15/97) after heterologous prime-boost immunization. Lungs from vaccinated animals showed minimal damage or inflammatory infiltrates post-challenge, in contrast to animals vaccinated with formalin-inactivated virus. Our results suggest that recombinant human adenoviral Ad26 and Ad35 vectors encoding the RSV F gene have the potential to provide broad and durable protection against RSV in humans, and appear safe to be investigated in infants.
Recombinant low-seroprevalent adenoviral vectors Ad26 and Ad35
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Arun kumar
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Arun kumar
Fluidized bed reactor for Anaerobic digestion of waste
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A microporous covalent triazine polymer (CTP) network with a high surface area was synthesized via the Friedel-Crafts reaction for anticancer drug delivery and controlled release. The CTP is transformed to the nanoscale region by intense ultasonication followed by filtration to yield nanoscale CTP (NCTP) with excellent dispersibility in physiological solution while maintaining its chemical structure and the porosity of the material. An anti-cancer drug, doxorubicin (DOX), is loaded onto the NCTP through simple physisorption by hydrophobic and π–π interactions, and its release can be controlled at acidic and neutral pH. The NCTP did not show practical toxicity to cancer and normal cells, but the NCTP-DOX complex showed high efficacy at killing both types of cells in-vitro. The prolonged drug release (over 50h) from the NCTP-DOX at neutral and acidic pH values was demonstrated. The in-vitro cell imaging results indicate that NCTP has good potential for bio-imaging. The cellular senescence and potency of NCTP was confirmed by the expression of senescence associated marker proteins p53 and p21. These results suggest that NCTP can be used as a new platform for imaging and drug delivery, which may find potential applications in diagnosis and therapy.
Porous Covalent Triazine Polymer as a Potential Nanocargo for Cancer Therapy ...
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We demonstrated a non-enzymatic cholesterol sensor based on a nickel oxide (NiO) and high quality graphene composite for the first time. Graphene was grown by a chemical vapor deposition technique (CVD). The nanocomposite was fabricated through the electrodeposition of nickel hydroxide onto the surface of the CVD-grown graphene, which was followed by thermal annealing. The successful formation of the NiO/graphene composite was confirmed by X-ray diffraction, X-ray photoelectron spectroscopy, and Raman spectroscopy. The deposition of flower-like NiO onto the graphene surface was confirmed by scanning electron microscopy. Electrochemical analyses were conducted to investigate the characteristics of the sensor during the detection of cholesterol. The sensor showed a high sensitivity of 40.6 mA mM1 cm2, a rapid response time of 5 s, and a low detection of limit of 0.13 mM. We also investigated the effects of common interfering substances on the ability of the sensor to detect cholesterol. Furthermore, we successfully determined the cholesterol in a milk sample using the developed sensor. The composite electrode exhibited excellent detection of cholesterol with good reproducibility and long-term stability owing to the combined effects of NiO and graphene.
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On episode 270 of the Digital and Social Media Sports Podcast, Neil chatted with Nirupam Singh, Creative Director, Ghostwriter, Strategic Consultant — motorsports and sports tech businesses.. What follows is a collection of snippets from the podcast. To hear the full interview and more, check out the podcast on all podcast platforms and at www.dsmsports.net
Nirupam Singh on Fan Development, Growth, and the Future of Formula 1
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Luka Modric Elevating Croatia's Stars for Euro Cup 2024.docx
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Klinik_ Apotek Onlin 085657271886 Solusi Menggugurkan Masalah Kehamilan Anda Jual Obat Aborsi Asli KLINIK ABORSI TERPEECAYA _ Jual Obat Aborsi Cytotec Misoprostol Asli 100% Ampuh Hanya 3 Jam Langsung Gugur || OBAT PENGGUGUR KANDUNGAN AMPUH MANJUR OBAT ABORSI OLINE" APOTIK Jual Obat Cytotec, Gastrul, Gynecoside Asli Ampuh. JUAL ” Obat Aborsi Tuntas | Obat Aborsi Manjur | Obat Aborsi Ampuh | Obat Penggugur Janin | Obat Pencegah Kehamilan | Obat Pelancar Haid | Obat terlambat Bulan | Ciri Obat Aborsi Asli | Obat Telat Bulan | Pil Aborsi Asli | Cara Menggugurkan Konten | Cara Aborsi Tuntas | Harga Obat Aborsi Asli | Pil Aborsi | Jual Obat Aborsi Cytotec | Cara Aborsi Sendiri | Cara Aborsi Usia 1 Bulan | Cara Aborsi Usia 2 Tahun | Cara Aborsi Usia 3 Bulan | Obat Aborsi Usia 4 Bulan | Cara Abrasi Usia 5 Bulan | Cara Menggugurkan Konten | Kandungan Obat Penggugur | Cara Menghitung Usia Konten | Cara Mengatasi Terlambat Bulan | Penjual Obat Aborsi Asli | Obat Aborsi Garansi | Kandungan Obat Peluntur | Obat Telat Datang Bulan | Obat Telat Haid | Obat Aborsi Paling Murah | Klinik Jual Obat Aborsi | Jual Pil Cytotec | Apotik Jual Obat Aborsi | Kandungan Dokter Abrasi | Cara Aborsi Cepat | Jual Obat Aborsi Bergaransi | Jual Obat Cytotec Asli | Obat Aborsi Aman Manjur | Obat Misoprostol Cytotec Asli. "APA ITU ABORSI" “Aborsi Adalah dengan membendung hormon yang di perlukan untuk mempertahankan kehamilan yaitu hormon progesteron, karena hormon ini dibendung, maka jalur kehamilan mulai membuka dan leher rahim menjadi melunak,sehingga mengeluarkan darah yang merupakan tanda bahwa obat telah bekerja || maksimal 1 jam obat diminum || PENJELASAN OBAT ABORSI USIA 1 _7 BULAN Pada usia kandungan ini, pasien akan merasakan sakit yang sedikit tidak berlebihan || sekitar 1 jam ||. namun hanya akan terjadi pada saatdarah keluar merupakan pertanda menstruasi. Hal ini dikarenakan pada usiakandungan 3 bulan,janin sudah terbentuk sebesar kepalan tangan orang dewasa. Cara kerja obat aborsi : JUAL OBAT ABORSI AMPUH dosis 3 bulan secara umum sama dengan cara kerja || DOSIS OBAT ABORSI 2 bulan”, hanya berbedanya selain mengisolasijanin juga menghancurkan janin dengan formula methotrexate dikandungdidalamnya. Formula methotrexate ini sangat ampuh untuk menghancurkan janinmenjadi serpihan-serpihan kecil akan sangat berguna pada saat dikeluarkan nanti. APA ALASAN WANITA MELAKUKAN ABORSI? Aborsi di lakukan wanita hamil baik yang sudah menikah maupun belum menikah dengan berbagai alasan , akan tetapi alasan yang utama adalah alasan-alasan non medis (termasuk aborsi sendiri / di sengaja/ buatan] MELAYANI PEMESANAN OBAT ABORSI SETIAP HARI, SIAP KIRIM KESELURUH KOTA BESAR DI INDONESIA DAN LUAR NEGERI. HUBUNGI PEMESANAN LEBIH NYAMAN VIA WA/: 085657271886
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We demonstrated a non-enzymatic cholesterol sensor based on a nickel oxide (NiO) and high quality graphene composite for the first time. Graphene was grown by a chemical vapor deposition technique (CVD). The nanocomposite was fabricated through the electrodeposition of nickel hydroxide onto the surface of the CVD-grown graphene, which was followed by thermal annealing. The successful formation of the NiO/graphene composite was confirmed by X-ray diffraction, X-ray photoelectron spectroscopy, and Raman spectroscopy. The deposition of flower-like NiO onto the graphene surface was confirmed by scanning electron microscopy. Electrochemical analyses were conducted to investigate the characteristics of the sensor during the detection of cholesterol. The sensor showed a high sensitivity of 40.6 mA mM1 cm2, a rapid response time of 5 s, and a low detection of limit of 0.13 mM. We also investigated the effects of common interfering substances on the ability of the sensor to detect cholesterol. Furthermore, we successfully determined the cholesterol in a milk sample using the developed sensor. The composite electrode exhibited excellent detection of cholesterol with good reproducibility and long-term stability owing to the combined effects of NiO and graphene.
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On episode 270 of the Digital and Social Media Sports Podcast, Neil chatted with Nirupam Singh, Creative Director, Ghostwriter, Strategic Consultant — motorsports and sports tech businesses.. What follows is a collection of snippets from the podcast. To hear the full interview and more, check out the podcast on all podcast platforms and at www.dsmsports.net
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Klinik_ Apotek Onlin 085657271886 Solusi Menggugurkan Masalah Kehamilan Anda Jual Obat Aborsi Asli KLINIK ABORSI TERPEECAYA _ Jual Obat Aborsi Cytotec Misoprostol Asli 100% Ampuh Hanya 3 Jam Langsung Gugur || OBAT PENGGUGUR KANDUNGAN AMPUH MANJUR OBAT ABORSI OLINE" APOTIK Jual Obat Cytotec, Gastrul, Gynecoside Asli Ampuh. JUAL ” Obat Aborsi Tuntas | Obat Aborsi Manjur | Obat Aborsi Ampuh | Obat Penggugur Janin | Obat Pencegah Kehamilan | Obat Pelancar Haid | Obat terlambat Bulan | Ciri Obat Aborsi Asli | Obat Telat Bulan | Pil Aborsi Asli | Cara Menggugurkan Konten | Cara Aborsi Tuntas | Harga Obat Aborsi Asli | Pil Aborsi | Jual Obat Aborsi Cytotec | Cara Aborsi Sendiri | Cara Aborsi Usia 1 Bulan | Cara Aborsi Usia 2 Tahun | Cara Aborsi Usia 3 Bulan | Obat Aborsi Usia 4 Bulan | Cara Abrasi Usia 5 Bulan | Cara Menggugurkan Konten | Kandungan Obat Penggugur | Cara Menghitung Usia Konten | Cara Mengatasi Terlambat Bulan | Penjual Obat Aborsi Asli | Obat Aborsi Garansi | Kandungan Obat Peluntur | Obat Telat Datang Bulan | Obat Telat Haid | Obat Aborsi Paling Murah | Klinik Jual Obat Aborsi | Jual Pil Cytotec | Apotik Jual Obat Aborsi | Kandungan Dokter Abrasi | Cara Aborsi Cepat | Jual Obat Aborsi Bergaransi | Jual Obat Cytotec Asli | Obat Aborsi Aman Manjur | Obat Misoprostol Cytotec Asli. "APA ITU ABORSI" “Aborsi Adalah dengan membendung hormon yang di perlukan untuk mempertahankan kehamilan yaitu hormon progesteron, karena hormon ini dibendung, maka jalur kehamilan mulai membuka dan leher rahim menjadi melunak,sehingga mengeluarkan darah yang merupakan tanda bahwa obat telah bekerja || maksimal 1 jam obat diminum || PENJELASAN OBAT ABORSI USIA 1 _7 BULAN Pada usia kandungan ini, pasien akan merasakan sakit yang sedikit tidak berlebihan || sekitar 1 jam ||. namun hanya akan terjadi pada saatdarah keluar merupakan pertanda menstruasi. Hal ini dikarenakan pada usiakandungan 3 bulan,janin sudah terbentuk sebesar kepalan tangan orang dewasa. Cara kerja obat aborsi : JUAL OBAT ABORSI AMPUH dosis 3 bulan secara umum sama dengan cara kerja || DOSIS OBAT ABORSI 2 bulan”, hanya berbedanya selain mengisolasijanin juga menghancurkan janin dengan formula methotrexate dikandungdidalamnya. Formula methotrexate ini sangat ampuh untuk menghancurkan janinmenjadi serpihan-serpihan kecil akan sangat berguna pada saat dikeluarkan nanti. APA ALASAN WANITA MELAKUKAN ABORSI? Aborsi di lakukan wanita hamil baik yang sudah menikah maupun belum menikah dengan berbagai alasan , akan tetapi alasan yang utama adalah alasan-alasan non medis (termasuk aborsi sendiri / di sengaja/ buatan] MELAYANI PEMESANAN OBAT ABORSI SETIAP HARI, SIAP KIRIM KESELURUH KOTA BESAR DI INDONESIA DAN LUAR NEGERI. HUBUNGI PEMESANAN LEBIH NYAMAN VIA WA/: 085657271886
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Thigh Knee Calf Ankle Foot
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