2. Terumo BCT is the world leader in blood
component technologies.
We believe in the potential of blood to do
even more for patients than it does today.
This belief unites our organization, inspires
our innovation and strengthens our
collaboration with customers.
ll b ti ith t
Terumo BCT
Unlocking the Potential of Blood
2
3. Unlocking the Potential of Blood
Our focus, working with one of the world’s
most vital resources to ensure the lifesaving
gift of blood is available to p
g patients g
globally
y
Our future together, to think new and differently, to strive
for higher levels of performance to ensure our products
performance,
and services enable customers to reap new benefits and
outcomes
Our scientific insight, engineering abilities and manufacturing in
collaboration with customers to innovate technologies and discover new
ways t use current technologies t i
to t t h l i to increase productivity, efficiency and
d ti it ffi i d
patient care
4. Looking at Terumo BCT at a glance
Parent company: Terumo Corporation
Division: Blood Management Business
Chairman: David Perez
Revenues: In excess of $875M in FY2011
President and CEO: David Perez
Associates: More than 2,500 globally
Classification: Medical Device Manufacturer
Industry: Blood Banking, Transfusion Medicine,
Cell Therapies and Cell Processing
Customer segments: Blood Centers Hospitals and Therapeutic Apheresis
Centers,
Centers, and Biotech and Cell Processing
Global headquarters: Lakewood, Colorado, United States
Regional headquarters: Brussels, Buenos Aires, Hong Kong, Tokyo
Major manufacturing facilities: China, India, Japan, Northern Ireland, United States
4
5. Working to satisfy customer needs wherever
customers are l
t located
t d
Terumo BCT does business in more than 120 countries
▲ Terumo BCT has manufacturing locations in 5 countries
This map is a symbolic representation
s ap s sy bo c ep ese a o
5
6. Listening to our customers inspires our
commitment to innovation and our quest to deliver
higher levels of quality, safety and efficiency
COBE® SSpectra
t Trima
Apheresis System Collection Atreus® Spectra Optia®
System IMUFLEX® In-Line Whole Blood Apheresis TACSI®
Processing System System WB
Filter System
Est. 2012
T-ACE II T-RAC II
Mirasol®
System
Manager Reveos
Automated
TERUFLEX® HEMOQUICK T-ACE
TSCD® II Blood
Blood Bag System
Processing
Invented System
Vista® Atreus® Mirasol
LRS® Est. 2012
Information System Platelet
technology
System Manager TACSI in PAS
1969 2012
Atreus
Components
Protocol
Double Mirasol® Cadence Data Trima
IMUGARD Platelet Pathogen Collection Automated
Products Reduction System System Quantum®
Red Cells
Cell
COBE® TERUSYS Trima Accel® OrbiSac Elutra® Cell (Plasma and
Platelets) Expansion
2991 Cell System Automated System Separation
System
Processor Blood Collection System
System
T-SEAL II
6 Product availability varies by country.
7. Providing a comprehensive product portfolio to
meet the needs of our customers
o r c stomers
Blood
Bl d Hospitals and
H it l d Biotech d
Bi t h and
Centers Therapeutic Apheresis Cell Processing
Centers
Striving to make even safer, Helping our customers bring Supporting researchers in
higher-quality transfusions even more treatment options to developing cell therapies that
available to more patients patients may fundamentally improve
globally health care
7
8. Focusing on adding value at every step in Blood
Centers
Blood C t
Bl d Center operations
ti
Donor Management: Matching each donor to better
collection options
Collections: Enhancing efficiency and flexibility
for in-center and mobile blood drives
Processing: Improving lab efficiency, blood component
g p g y p
quality and process control through automation
Pathogen Reduction: Working toward safer blood for
p
patients, with safe and simple p
, p procedures for operators
p
8 Product availability varies by country.
9. Offering the most comprehensive Blood
Centers
product range f Bl d C t
d t for Blood Centers
Donor Management DonorMAX
DonorMAX Program │Trima for Prediction
g │
of Donation (T-POD)│Productivity Tools
Trima Accel
System
Collections
Trima Accel System │ Cadence Data Collection System │
O t R i │Vi t Information S t │
Outcome Review│Vista I f ti System│
Trima Accel Reporter│TOMEs Data Management Software│
T-RAC II System │IMUFLEX In-Line Filter System│
TERUFLEX/
TERUFLEX Blood Bag System│Atreus Whole Blood Processing System IMUFLEX
Disposables │ Blood Collection Accessories │Solutions
Processing
Atreus System │TACSI System│OrbiSac System │T-ACE II+ Blood
Component Expressor │T-SEAL II and Teruseal Tube Sealers│
TSCD II, TSCD and SCD II B Sterile Tube Welders│ Reveos System
(Est. 2012)
Atreus System Manager│Cadence Data Collection System
TACSI System
Pathogen Reduction
Mirasol System │Mirasol Manager
Mirasol System
9 Product availability varies by country.
10. Helping Blood Centers diversify Blood
Centers
and grow in new di
d i directions
ti
Offering therapeutic apheresis:
Expands treatment options for patients
Includes plasmapheresis, cytapheresis and red
blood cell exchange
Is possible in freestanding clinics, dedicated
centers or in conjunction with l
t i j ti ith local h
l hospitals
it l
Expanding into cell therapy:
Has the potential to fundamentally change the
way many diseases are treated
Includes cell collections, secondary processing
and expansion
Enables scalable production of cell therapies
Product availability varies by country.
10
11. Terumo BCT is the only company leveraging unique technology
technology,
innovation and core competencies in therapeutic apheresis, cell
collections and cell processing
Hospitals and Therapeutic
Apheresis Centers Biotech and Cell Processing
Improving the lives of patients with powerful Providing devices that wash, separate,
and flexible platforms to treat multiple disease concentrate and culture cells for research,
states industry and clinical use as well as dependable
use,
tools for supporting sterile lab applications
Sterile Connection
Devices Elutra
El t Quantum
COBE 2991
Spectra Optia System COBE Spectra System System System
Cell Processor
11 Product availability varies by country.
12. Biotech and
Supporting the cell processing value Cell Processing
chain f
from end to end
Cell Cell Cell Cell Washing and Cell g
Storage
collection isolation analysis expansion concentration analysis and
distribution
Activity:
Cells
C ll are Cells are
C ll Cell
C ll population
l ti Cells
C ll are Cells are
C ll Cell
C ll population
l ti Cells
C ll are stored
t d
collected from separated and is analyzed expanded washed or is analyzed prior to patient
bone marrow, sorted and (cultured) concentrated and administration
cord blood, characterized and/or prior to storage characterized
tissue or modified or
p p
peripheral administration
blood
Products:
COBE Spectra
p COBE 2991 cell Quantum COBE 2991 cell TSCD II
system processor system processor
(cell expansion)
Spectra Optia Elutra system Elutra system
system (elutriation) TSCD II (elutriation)
TSCD II
12 Product availability varies by country.
13. Enabling scalable production of Biotech and
Cell Processing
cell th
ll therapies
i
Traditional methods of cell expansion may be cost prohibitive to scale, and require:
A skilled labor force
Expensive equipment and facilities
Complex requirements and manual processes, which may compromise commercial viability
Our automated cell expansion provides scalability, which:
Is relevant for pre-clinical research through large-scale manufacturing
Minimizes the need to revalidate or revisit manufacturing methods later
Potentially
P t ti ll accelerates ti
l t time t market
to k t
Complements well-established, closed secondary processing technologies
We d li
W deliver well-established solutions for related cell processes, such as:
ll t bli h d l ti f l t d ll h
Washing
Concentration
Enrichment
Depletion
Our fast, strong, sterile welds are critical to establishing and maintaining:
Portable tubing welders
Quality function when used in a wide range of specialties
Durability and longevity
13 Product availability varies by country.
14. Believing in the potential of blood to do even
more f patients th it d
for ti t than does t d today
This belief unites our organization, inspires our innovation
and strengthens our collaboration with customers to
ultimately b
lti t l benefit th patients we all serve.
fit the ti t ll
14
15. “You create technology that allows life.” Laura Fraser
“Each day is such a gift to me.” Christy Cassidy
Sisters Christy and Laura are now free of non-Hodgkin's Lymphoma
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