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MENSTRUAL CYCLE
NORMAL MENSTRUAL CYCLE
mean duration of the MC
Mean 28 days (only 15% of )
Range 21-35
average duration of menses
3-8 days
normal estimated blood loss
Approximately 30 ml
ovulation occur
Usually day 14
36 hrs after the onset of mid-cycle LH surge
NORMAL MENSTRUAL CYCLE
the phases of the MC & ovulation regulates by:
Interaction between hypothalamus, pituitary & ovaries
mean age of menarche & menopause are:
Menarche
Menopause
12.7
51.4
The Cycle
• Strongly linked to the endocrine system
(hormone based and paracrine based)
• Typically takes 28 days to cycle through 4
phases
– Follicular
– Ovulation
– Luteal
– Menstruation
• Hormones raise and fall
Ovulation
Follicular
• Begins when estrogen levels are low
• Anterior pituitary secretes FSH and LH,
stimulation follicle to develop
• Cells around egg enlarge, releasing
estrogen
• This causes this uterine lining to thicken
Ovulation
• LH and FSH still being released, for
another 3-4 days
• Follicle ruptures, releasing ova into the
Fallopian tubes
Luteal
• Now empty follicle changes to a yellow
colour, becomes corpus luteum
• Continues to secrete estrogen, but now
beings to release progesterone
• Progesterone further develops uterine
lining
• If pregnant, embryo will release hormones
to preserve corpus luteum
Menstruation
• Menstruation
• If no embryo, the corpus luteum begins to
disintegrate
• Progesterone levels drop, uterine lining
detaches, menstruation can begin
• Tissue, blood, unfertilized egg all
discharged
• Can take from 3-7 days
HYPOTHALAMIC- PITUITARY- OVARIAN AXIS
prof. aj
Abnormal Uterine Bleeding
Abnormal uterine bleeding refers to uterine bleeding outside
of the parameters noted below :
 Duration greater than eight days
 Flow greater than 80 mL/cycle or subjective impression of
heavier-than-normal flow (ie, more than six full pads or
tampons per day)
 Occur more frequently than every 24 days or less frequently
than every 38 days
 Intermenstrual bleeding or postcoital spotting
 Absence of menses
+
 Oligomenorrhea: menstruation occurring with intervals of more than
35 days
 Polymenorrhea: menstruation occurring regularly with intervals of less
than 21 days
 Metrorrhagia: menstrual bleeding occurring at irregular intervals or
bleeding between menstrual cycles
 Menorrhagia: regular menstrual cycles with excessive flow (technically
more than 80 mL of volume) or menstruation lasting more than 7 days
 Menometrorrhagia: menstrual bleeding occurring at irregular intervals
with excessive flow or duration
Thank you

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menstrual cycle

  • 2. NORMAL MENSTRUAL CYCLE mean duration of the MC Mean 28 days (only 15% of ) Range 21-35 average duration of menses 3-8 days normal estimated blood loss Approximately 30 ml ovulation occur Usually day 14 36 hrs after the onset of mid-cycle LH surge
  • 3. NORMAL MENSTRUAL CYCLE the phases of the MC & ovulation regulates by: Interaction between hypothalamus, pituitary & ovaries mean age of menarche & menopause are: Menarche Menopause 12.7 51.4
  • 4. The Cycle • Strongly linked to the endocrine system (hormone based and paracrine based) • Typically takes 28 days to cycle through 4 phases – Follicular – Ovulation – Luteal – Menstruation • Hormones raise and fall
  • 6. Follicular • Begins when estrogen levels are low • Anterior pituitary secretes FSH and LH, stimulation follicle to develop • Cells around egg enlarge, releasing estrogen • This causes this uterine lining to thicken
  • 7. Ovulation • LH and FSH still being released, for another 3-4 days • Follicle ruptures, releasing ova into the Fallopian tubes
  • 8. Luteal • Now empty follicle changes to a yellow colour, becomes corpus luteum • Continues to secrete estrogen, but now beings to release progesterone • Progesterone further develops uterine lining • If pregnant, embryo will release hormones to preserve corpus luteum
  • 9. Menstruation • Menstruation • If no embryo, the corpus luteum begins to disintegrate • Progesterone levels drop, uterine lining detaches, menstruation can begin • Tissue, blood, unfertilized egg all discharged • Can take from 3-7 days
  • 10.
  • 11.
  • 14. Abnormal Uterine Bleeding Abnormal uterine bleeding refers to uterine bleeding outside of the parameters noted below :  Duration greater than eight days  Flow greater than 80 mL/cycle or subjective impression of heavier-than-normal flow (ie, more than six full pads or tampons per day)  Occur more frequently than every 24 days or less frequently than every 38 days  Intermenstrual bleeding or postcoital spotting  Absence of menses
  • 15. +  Oligomenorrhea: menstruation occurring with intervals of more than 35 days  Polymenorrhea: menstruation occurring regularly with intervals of less than 21 days  Metrorrhagia: menstrual bleeding occurring at irregular intervals or bleeding between menstrual cycles  Menorrhagia: regular menstrual cycles with excessive flow (technically more than 80 mL of volume) or menstruation lasting more than 7 days  Menometrorrhagia: menstrual bleeding occurring at irregular intervals with excessive flow or duration
  • 16.