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ALKALOIDS – GENERAL
INTRODUCTION
By,
Dr. P. Arthanariswaran.,
Professor & Head,
Department of Pharmacognosy,
Nirmala college of Health Science,
Chalakudy, Kerala
ALKALOIDS – GEN. INTRO
Alkaloids are defined as basic organic heterocyclic nitrogenous compounds
containing one or more nitrogen atom and are physiologically active in small
concentration.
Alkaloids are also called as PFLANZENKALEIN. The name was first
coined by the german pharmacist MEISSNER IN 1819.
General Properties:
All alkaloids are generally colourless, crystalline compounds with sharp melting
point
Alkaloids generally occurs as salts and sometimes as free bases
Alkaloidal salts are soluble in water whereas free alkaloids are soluble in non
polar solvents
ALKALOIDS – GEN. INTRO
 Generally bitter in taste
 Helps plants in fighting against insects & microbes
 Posses numerous pharmacological properties and is based on the chemical constituents
present in the particular crude drug.
Identification test:
1. With dragendorff’s reagent – Reddish brown precipitate
2. With Mayer’s reagent – Cream coloured precipitate
3. With Hager’s reagent – Yellow colour
4. With Wagner’s reagent – Reddish brown precipitate
ALKALOIDS – GEN. INTRO
Classification of alkaloids
I. Based on its origin,
1. True alkaloids
2. Proto alkaloids
3. Pseudo alkaloids
ALKALOIDS – GEN. INTRO
II. Based on its chemical nature:
1. Purine alkaloids Eg. Tea
2. Indole alkaloids Eg. Rauwolfia
3. Pyridine alkaloids Eg. Pepper
4. Phenanthrene alkaloids Eg. Opium
5. Quinoline alkaloids Eg. Cinchona
6. Tropane alkaloids Eg. Datura
7. Pyridine alkaloids Eg. Tobacco
8. Iso quinoline alkaloids Eg. Opium

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INTRODUCTION TO ALKALOIDS.pptx

  • 1. ALKALOIDS – GENERAL INTRODUCTION By, Dr. P. Arthanariswaran., Professor & Head, Department of Pharmacognosy, Nirmala college of Health Science, Chalakudy, Kerala
  • 2. ALKALOIDS – GEN. INTRO Alkaloids are defined as basic organic heterocyclic nitrogenous compounds containing one or more nitrogen atom and are physiologically active in small concentration. Alkaloids are also called as PFLANZENKALEIN. The name was first coined by the german pharmacist MEISSNER IN 1819. General Properties: All alkaloids are generally colourless, crystalline compounds with sharp melting point Alkaloids generally occurs as salts and sometimes as free bases Alkaloidal salts are soluble in water whereas free alkaloids are soluble in non polar solvents
  • 3. ALKALOIDS – GEN. INTRO  Generally bitter in taste  Helps plants in fighting against insects & microbes  Posses numerous pharmacological properties and is based on the chemical constituents present in the particular crude drug. Identification test: 1. With dragendorff’s reagent – Reddish brown precipitate 2. With Mayer’s reagent – Cream coloured precipitate 3. With Hager’s reagent – Yellow colour 4. With Wagner’s reagent – Reddish brown precipitate
  • 4. ALKALOIDS – GEN. INTRO Classification of alkaloids I. Based on its origin, 1. True alkaloids 2. Proto alkaloids 3. Pseudo alkaloids
  • 5. ALKALOIDS – GEN. INTRO II. Based on its chemical nature: 1. Purine alkaloids Eg. Tea 2. Indole alkaloids Eg. Rauwolfia 3. Pyridine alkaloids Eg. Pepper 4. Phenanthrene alkaloids Eg. Opium 5. Quinoline alkaloids Eg. Cinchona 6. Tropane alkaloids Eg. Datura 7. Pyridine alkaloids Eg. Tobacco 8. Iso quinoline alkaloids Eg. Opium