2. Objectives
Gain a general understanding of the nervous system
Gain knowledge of the structure and function of the neuron
Navigate your way around the major brain areas and
understand their function
4. Central nervous system
Brain
~2% of body weight, uses ~20% of resources
Composed of bunches of neurons, which form nerves
Spinal cord
Complex tangle of nerves that stretch from brain to tailbone
Collects & transmits info between brain and peripheral nervous
system
Also initiates reflexes: automatic responses to an event
5. Peripheral Nervous System
PNS links the CNS to the organs, muscles, and glands of
the body
PNS has two parts
Somatic (SNS): nerves controlling voluntary muscle
movements
Autonomic (ANS): controls glands, organs, blood vessels
ANS has two parts
Sympathetic: arouses body to prepare for action (fight or flight)
Parasympathetic: slows down body to reserve energy
7. The Neuron
All brain activity originates with the neuron
The messengers of the brain-world
These cells receive signals from neurons or sense organs,
process the signals, and send them to other neurons, muscles,
or organs
Three types
Sensory: respond to sensory organ input
Motor: send signals to muscles to control movement
Interneurons: the go-between of sensory and motor neurons
We have about 100 billion neurons
Most, but not all, can be re-grown (severe spinal cord injury vs.
cutting your finger)
9. The Neuron: Structure
Cell body: houses nucleus
Cell Membrane: skin of the cell
Axon: cable extending from the cell body
Impulse from cell body travels along axon to its end, where
terminal buttons release neurotransmitters (chemical
messengers), received by other neurons
Axon is covered by myelin sheath, which is composed of a fatty
substance that helps impulses travel the length of the axon
Dendrite
Branches extending from cell membrane that receive
neurotransmitters from other neurons
10. The Dendrite
Increases receptive surface of the neuron
Contacts occur along surface of dendrite
11. The Axon
Axon hillock
Myelin sheath
Nodes of Ranvier
The points just
between the myelin
sheaths
12. The Neuron in Action
When a neuron receives impulses from other neurons, the
cell membrane allows open exchange of positively and
negatively charged ions
Action potential (change in electrical charge) runs down axon
to terminal buttons
This all starts with the axon hillock – the gatekeeper of the
neuron
Terminal buttons release neurotransmitters
Neurotransmitters cross the synaptic cleft to the dendrite of the
receiving neuron
14. Communication in the Neuron
All-or-nothing
The action potential either happens or it doesn’t
Non-decremental
Action potentials don’t change in amount (voltage) as they
travel
Refractory period
Neurons need 2ms to recover before they can transmit again
Threshold
The minimum level of stimulation required to trigger a neural
impulse
Once you reach the threshold, the action potential doesn’t get
bigger
15. Important Neurotransmitters
Acetylcholine (Ach)
Slows down the body, memory, and attention (involved in Alzheimer’s
disease)
Dopamine (DA)
Voluntary movement, attention, and learning; high levels are
associated w/schizophrenia
Endorphin
Reduce sensitivity to pain; linked with pleasure (opiate-like)
Serotonin
Arousal, sleep; Prozac increases levels of serotonin
Norepinephrine
Helps control alertness and arousal; low levels can depress mood
16. History of Studying the Brain
Franz Joseph Gall (1758 – 1828)
Phrenology
The study of the structure of the skull to determine a person’s
character and mental capacity
26 ‘organs’ on the surface
of the brain
18. History of Studying the Brain
Flourens (1794 – 1867)
Emphasized the importance of experimental research of the
brain
Carefully controlled experiments on animals to determine
localities of brain and their functions
Moved the field of brain research into a more scientific arena
20. Five Major Brain Areas
CEREBRAL CORTEX is involved in your higher mental functions
of perceptual awareness, recognition and interpretation of sensory
stimuli (mostly based on memories).
PREFRONTAL CORTEX is involved in your conscious thinking
processes, especially making choices by using your brainpower
LIMBIC SYSTEM is involved in the expression of your instincts
and feeling processes, including your moods, since it includes your
hypothalamus and amygdala parts;
CEREBELLUM is involved in your posture and many coordinated
movements;
BRAINSTEM controls your body's most basic unconscious life-
sustaining functions, including your breathing and heartbeat.
21. Cerebral Cortex
Two halves, four lobes
Frontal lobe (seat of intelligence)
Motor cortex (walking, chewing)
Parietal lobe
Sensory cortex
Prosopagnosia (face blindness)
Unilateral neglect (only realize half)
Temporal lobe
Auditory areas (opposite ear)
Occipital lobe
Visual areas (opposite eye)
22. Prefrontal Cortex
The prefrontal cortex (PFC) is the very front of the brain,
located right beneath the forehead. It is in the anterior (front)
region of the frontal lobes.
It is responsible for the executive functions, which include
mediating conflicting thoughts, making choices between
right and wrong or good and bad, predicting future events,
and governing social control — such as suppressing
emotional or sexual urges.
The prefrontal cortex is the brain center most strongly
implicated in qualities like sentience, human general
intelligence, and personality.
24. Cerebellum
The cerebellum (Latin for little brain) is a region of the
brain that plays an important role in motor control. It is
also involved in some cognitive functions such as
attention and language, and probably in some
emotional functions such as regulating fear and
pleasure responses.
25. Brain Mapping
How your brain is laid out. Actually, how any animals
brain is laid out.
Two parts, linked together, but functioning as one
unit/different units.
Distinct differences between hemispheres. Left
handed-ness or right handed-ness.
27. Two Cerebral Hemispheres
Contralateral arrangement
Corpus callosum
Thick band of nerve fibers connecting the hemispheres
It’s how the 2 hemispheres communicate
Right-brained vs. left-brained? Bicamerialism??
OR
28. Brain Stem
Region of the brain where the spinal cord enters the skull
and swells
Medulla
Regulates heart-rate, breathing, blood pressure, and motor
movements
Cerebellum
Controls skilled motor movements
29. Brain Stem
Pons
Connects the two hemispheres of the cerebellum
Reticular formation
Sleep
Attention
Thalamus
Relay center
Filters & organizes information from senses