Revision with a Master Quiz of 7 questions based on NEET PG Sample Questions on Schwannoma from Previous Year NEET PG Online Exams.

1. A patient with vestibular schwannoma is best investigated by which of the following:
A: SPECT
B: Contrast enhanced CT scan
C: Gadolinum enhanced MRI
D: PET scan
Correct Ans:C
Explanation
Vestibular schwannoma usually arises in VIII cranial nerve of posterior cranial fossa. CT
scan will not give clear picture of posterior cranial fossa tumour < 2cm. MRI scan is the
investigation of choice in patient with posterior cranial fossa tumour.
Ref: Philippe Demaerel, (2001), Chapter 18, “Imaging of Intracranial Abnormalities in
Neurofibramatosis type 1 & 2”, In the book, ”Recent Advances in Diagnostic
Neuroradiology”, Springer Publications, USA, Page 283
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A 40-years-old female patient presented with recurrent headaches. MRI showed an extra-
axial, dural based and enhancing lesion. The most likely diagnosis is:
A: Meningioma
B:
Gliom
a
C: Schwannoma
D: Pituitary' adenoma
Correct Ans:A
Explanation
Meningioma can present with headaches, seizures, or focal neurologic deficits. On imaging
studies they have a characteristic appearance usually consisting of a partially calcified,
densely enhancing extra axial tumor arising from the dura. Occasionally they may have a
dural tail, consisting of thickened, enhanced dura extending like a tail from the mass.
Ref: DeAngelis L.M., Wen P.Y. (2012). Chapter 379. Primary and Metastatic Tumors of the
Nervous System. In D.L. Longo, A.S. Fauci, D.L. Kasper, S.L. Hauser, J.L. Jameson, J.
Loscalzo (Eds), Harrison's Principles of Internal Medicine, 18e.

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HMB 45 is an immuno-histological marker for
A: Melanoma
B: Schwannoma
C: Neurofibroma
D: Rhabdomyosarcoma
Correct Ans:A
Explanation
HMB - 45 is an immunohistological marker for Melanoma.
Ref: Quick Reference Handbook for Surgical Pathologists By Natasha Rekhtman, Justin A.
Bishop, Page 12; Harrison's Principles of Internal Medicine, 16th Edition, Pages 439, 563
and 17th Edition, Page 615
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What will be the most likely diagnosis in a 70 year old male with hypo-aesthesia of external
auditory meatus (Histelberg's sign positive)?
A: Mastoiditis
B:
Bells
palsy
C: Vestibular schwannoma
D: Middle ear cholesteatoma
Correct Ans:C
Explanation
Hitzelberg’s sign refers to hypo-aesthesia of the posterosuperior aspect of the external
meatus.It is due to involvement of nervus intermedius (sensory root of VIIth nerve).
Ref: Hearing Loss, Peter S. Roland, Chapter 7, Page 247; Diseases of Ear, Nose and Throat,
PL Dhingra, 4th Edition, Page 110, 111

3. Sample Previous Year Question on Schwannoma based on previous Year
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Schwannoma arises most frequently from:
A: Vestibular Nerve
B: Trigeminal nerve
C: Cochlear Nerve
D: Facial Nerve
Correct Ans:A
Explanation
A schwannoma (also known as acoustic neuroma, acoustic neurinoma, or acoustic neurilemoma) is a
benign, usually slow-growing tumor that develops from the vestibular nerves supplying the inner ear.
The tumor comes from an overproduction of Schwann cells--the cells that normally wrap around nerve
fibers like onion skin to help support and insulate nerves. As the vestibular schwannoma grows, it
presses against the hearing and balance nerves, usually causing unilateral (one-sided) or asymmetric
hearing loss, tinnitus (ringing in the ear), and dizziness/loss of balance. It comprises 5-10% of all
intracranial neoplasms in adults. Incidence peaks in the fifth and sixth decades and both sexes are
affected equally.
Ref: 'Neurology' by Bodie (Thieme) 1st (2006)/222; 'Handbook of Clinical Neurology' by
Vinken &Bruyn 1st (1997)/933.
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Vestibular Schwannoma arises most frequently from:
A: Superior Vestibular Nerve
B:
Inferior Vestibular
Nerve
C: Cochlear Nerve
D: Facial Nerve
Correct Ans:A
Explanation

4. Superior Vestibular nerve is the most common nerve of origin, followed by Inferior
Vestibular Nerve. Vestibular Schwannoma is traditionally believed to arise more frequently
from the superior division of the vestibula.
Ref: Otology, Neurotology and Lateral Skull Base Surgery By Oliver Adunka, Craig Buchman,
Page 374; Logan Turner, 10th Edition, Page 339
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Which is the most common retrobulbar orbital mass in adults?
A: Meningioma
B: Neurofibroma
C: Schwannoma
D: Cavernous hemangioma
Correct Ans:D
Explanation
Cavernous hemangiomas are the most common benign orbital tumors in adults. This tumor
is usually located in the retroorbital cone. It is composed of numerous dilated vascular
spaces of variable size and are surrounded by a fibrous capsule.
On CT and MRI, the tumor appear as sharply marginated, round to oval, somewhat flattened
mass that abut from the posterior wall of the globe.
Ref: Diagnostic and Interventional Neuroradiology By Klaus Sartor, G. Albrecht, Page 135.
Sample Previous Year Question on Schwannoma based on previous Year
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