This document summarizes the results of a study on the effectiveness of the drug itopride in treating functional dyspepsia. The study found that: - Itopride was significantly more effective than placebo in improving symptom severity scores and response rates based on patients' global assessments of efficacy. - A higher dose of itopride (100mg and 200mg) was more effective than a lower dose (50mg) or placebo in improving response rates. - Quality of life scores improved more for patients taking itopride than placebo, though differences between itopride doses were not significant. The study provides evidence that itopride is effective in treating functional dyspepsia compared to placebo

1. CRISBERT I. CUALTEROS, M.D. Department of Family and Community Medicine Perpetual Succour Hospital

14. A positive response: improvement by at least one grade

21. Holtmann G et al. N Engl J Med 2006;354:832-840 Response Rates Based on Patients' Global Assessment of Efficacy

23. Primary Outcome Variables among 523 Patients