Pancreatic Neoplasms

Universidad de Guadalajara Noviembre 2011 Pancreatic Neoplasms Centro Universitario Ciencias de la Salud Clínicas Quirúrgicas Mayra C. Silva Camarena 206558747 Dr. Benjamin Robles Mariscal Dr. Héctor Manuel Virgen Ayala

E ndocrine E xocrine Functional No functional

[object Object],R are F unctional M alignant 5 / 1 000000 /365 secreted peptide products

I nsulinoma ,[object Object],90 % solitary beningnos 10 % malignant Head = B ody = T ail

[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],C linical M anifestations β Whipple's triad

D iagnosis ,[object Object],0 :3

[object Object],T reatment CT Endoscopic ultrasound Surgical treatment Simple enucleation Partial-pancreatomy Pancreatoduodenectomy Medical Treatment Diaxozido

[object Object],[object Object],[object Object],[object Object],G astrinoma

[object Object],C linical M anifestations Z ollinger E llison s yndrome G astrin Abdominal pain Peptic ulcer disease Severe esophagitis Multiple ulcers Diarrhea

[object Object],[object Object],D iagnosis Location S omatostatin receptor scintigraphy + TAC E ndoscopic ultrasound

VIP oma ,[object Object],[object Object],[object Object]

[object Object],C linical M anifestations Watery diarrea Hipokalemia Aclorhidia Metabolic acidosis Hypercalcemia Extreme weakness

[object Object],[object Object],[object Object],D iagnosis

[object Object],T reatment S omatostatin analogs F luids and electrolytes Surgical E xtraction of the tumor Streptozocin

G lucagoma ,[object Object],[object Object],α 2

[object Object],C linical M anifestations N ecrolytic m igratory d ermatitis Weight loss Stomatitis Hipoaminoacidemia Anemia

[object Object],[object Object],D iagnosis

[object Object],T reatment Control of diabetes mellitus Parenteral nutrition Octreotide S urgical treatment E xtraction of the tumor Streptozocin

S omatostatinoma ,[object Object],Diagnosis: somatostatin serum (10ng/ml)

Treatment: ,[object Object],[object Object],Streptozocin

No functional ,[object Object],[object Object],Clinical: abdominal and back pain, weight loss, jaundice, palpable mass.

[object Object],[object Object]

[object Object],Risk factors Smoking Diabetes Chronic pancreatitis Alcohol consumption Coffee consumption, Diet high in fat and low in fiber Family History

D uctal adenocarcinoma ,[object Object],75 % Head 15% B ody 10%T ail CA 19-9

[object Object],C linical M anifestations Jaundice -44kg Abdominal pain Hepatomegaly Coourvoisier sign BODY-TAIL Abdominal pain Weight loss ALKALINE PHOSPHATASE BILIRUBIN

[object Object],[object Object],[object Object],Tomor Criter Unresectable -Invasion of the hepatic artery -Invasion of the superior mesenteric artery -Ascites -Distant metastases (liver) -Invasion to distant organs

Whipple procedure Pancreatoduenoctomy Cholecystojejunostomy Percutaneous endoprostheses Gastroyeyunostonia Chemotherapy

jaundice gastrointestinal bleeding weight loss pain ,[object Object]

[object Object],Pancreatoduodenectomy Sphincterotomy

[object Object],[object Object],37 % 3 6 % 26 %

D iagnosis ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Thickening of the anterior renal fascia, peripancreatic edema, diffuse enlargement of the gland, observation of the fracture, hematoma or the presence of pancreatic fluid separating the splenic vein or pancreatic body

T reatment E xternal drainage simple P ancreatorrafia using nonabsorbable sutures R esection of part of the gland distal P ancreatectomy and splenectomy

C omplications ,[object Object],8 - 18 % P ancreatic fistula P eripancreatic abscesses P ancreatitis

Pancreatic Neoplasms

Recommended

Recommended

More Related Content

What's hot

What's hot (20)

Viewers also liked

Viewers also liked (14)

Similar to Pancreatic Neoplasms

Similar to Pancreatic Neoplasms (20)

More from Clinicas Quirurgicas

More from Clinicas Quirurgicas (20)

Recently uploaded

Recently uploaded (20)

Pancreatic Neoplasms

Editor's Notes