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dentify 5 functional groups. Where on this molecule would you expect resonance? Are there any
special amines | amides? H2N Cys HN Pro Cys Leu Gin Asn H2N NH2 Gly o
Solution
WE can see an -OH group (on the benzene ring)
Primary amine -NH 2 ( near to where Cys is written)
Primary amide -CONH 2 (as a part of Gly)
Secondary amide -CONH
Tertiary amine -N ( in the 5 membered heterocyclic ring)
Resonance is possible due to Zwitter ion formations. H from -OH group of carboxylic acid
leaves as H +
which is accepted by lone pair of N of NH 2 group of amino acid.Special amines or
amides are not seen.
There is possibility of Hydrogen bonding between 1 and 2. Due to this acetic acid becomes
soluble in water.
There is a strong covalent bonding between 2 and 3. A weak Vaander waals force of attraction
exists between 4 and 5. Only the Hydrogen in the acid group can depart as H +
. H atoms from
CH 3 cannot leave as H +
That is why acetic acid is a monobasic acid.
dentify 5 functional groups- Where on this molecule would you expect r.docx

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dentify 5 functional groups- Where on this molecule would you expect r.docx

  • 1. dentify 5 functional groups. Where on this molecule would you expect resonance? Are there any special amines | amides? H2N Cys HN Pro Cys Leu Gin Asn H2N NH2 Gly o Solution WE can see an -OH group (on the benzene ring) Primary amine -NH 2 ( near to where Cys is written) Primary amide -CONH 2 (as a part of Gly) Secondary amide -CONH Tertiary amine -N ( in the 5 membered heterocyclic ring) Resonance is possible due to Zwitter ion formations. H from -OH group of carboxylic acid leaves as H + which is accepted by lone pair of N of NH 2 group of amino acid.Special amines or amides are not seen. There is possibility of Hydrogen bonding between 1 and 2. Due to this acetic acid becomes soluble in water. There is a strong covalent bonding between 2 and 3. A weak Vaander waals force of attraction exists between 4 and 5. Only the Hydrogen in the acid group can depart as H + . H atoms from CH 3 cannot leave as H + That is why acetic acid is a monobasic acid.