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Efferents
Neurotransmitters and receptors
Cholinergic fibers are nerve endings that
release acetylcholine.
Adrenergic fibers are nerve fibers that
release norepinephrine.
Cholinergic receptors
 Nicotinic receptors are acetylcholine-
 binding receptors that bind to nicotine.
 Muscarinic receptors are acetylcholine-
 binding receptors that bind to muscarine.
Adrenergic receptors
 Alpha is a type of adrenergic receptor that
 usually causes a stimulatory effect when it
 binds with norepinephrine or epinephrine.
 Beta adrenergic receptors usually cause an
 inhibitory effect when bound to NE or
 epinephrine.
Interactions of the autonomic
divisions
Sympathetic and
parasympathetic tone
 Sympathetic tone is a state of partial
 vasoconstriction of the blood vessels
 maintained by sympathetic fibers.
 Vasomotor fibers are sympathetic nerve
 fibers that regulate the contraction of
 smooth muscle in the walls of blood
 vessels.
Parasympathetic tone is a state of
parasympathetic effects that prevents
unnecessary heart accelerations and
promotes normal digestive activity.
Effects of the parasympathetic
and sympathetic divisions on
various organs
Target organ/system      Parasympatheic effects          Sympathetic effects
Eye (iris)               Constricts pupils               Dilates pupils
Eye (ciliary mucle)      Stimulates muscles for close    No effect
                         accomodation of lens
Glands                   Stimulates secretory activity   Inhibits secretory activity
Sweat glands             No effect                       Stimulates copious sweating
Adrenal medulla          No effect                       Stimulates secretion of epinephrine
                                                         and norepinephrine
Arrector pili muscles    No effect                       Stimulates contraction
Heart muscle             Decreases rate                  Increase rate and force
Coronary blood vessels   Constricts                      Causes vasodilation
Bladder/urethra          Relax urethral sphincter;       Constricts urethral sphincter;
                         promotes voiding                inhibits voiding
Lungs                    Constricts bronchioles          Dilates bronchioles
Target organ/system      Parasympatheic effects      Sympathetic effects
Digestive tract organs   Increases peristalsis       Decreases glandular acivity and
                                                     constricts sphincters
Liver                    No effect                   Releases glucose into blood
Gall bladder             Stimulates bile secretion   Inhibits bile secretion
Kidney                   No effect                   Decreases urine output; vasoconstriction
Penis                    Causes erection             Causes ejaculation
Vagina/clitoris          Causes erection             Reverse peristalsis
Blood vessels            No effect                   Constricts blood vessels, increases
                                                     blood pressure
Blood coagulation        No effect                   Increases coagulation
Cellular metabolism      No effect                   Increases metabolic rate
Adipose tissue           No effect                   Stiulate lipolysis
Mental activity          No effect                   Increases altertness
Control of autonomic functioning
Cortical controls
 Biofeedback training provides an awareness
 of visceral activities, enabling an element of
 voluntary control over autonomic body
 functions.

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Efferents

  • 3. Cholinergic fibers are nerve endings that release acetylcholine. Adrenergic fibers are nerve fibers that release norepinephrine.
  • 4. Cholinergic receptors Nicotinic receptors are acetylcholine- binding receptors that bind to nicotine. Muscarinic receptors are acetylcholine- binding receptors that bind to muscarine.
  • 5. Adrenergic receptors Alpha is a type of adrenergic receptor that usually causes a stimulatory effect when it binds with norepinephrine or epinephrine. Beta adrenergic receptors usually cause an inhibitory effect when bound to NE or epinephrine.
  • 6. Interactions of the autonomic divisions
  • 7. Sympathetic and parasympathetic tone Sympathetic tone is a state of partial vasoconstriction of the blood vessels maintained by sympathetic fibers. Vasomotor fibers are sympathetic nerve fibers that regulate the contraction of smooth muscle in the walls of blood vessels.
  • 8. Parasympathetic tone is a state of parasympathetic effects that prevents unnecessary heart accelerations and promotes normal digestive activity.
  • 9. Effects of the parasympathetic and sympathetic divisions on various organs
  • 10. Target organ/system Parasympatheic effects Sympathetic effects Eye (iris) Constricts pupils Dilates pupils Eye (ciliary mucle) Stimulates muscles for close No effect accomodation of lens Glands Stimulates secretory activity Inhibits secretory activity Sweat glands No effect Stimulates copious sweating Adrenal medulla No effect Stimulates secretion of epinephrine and norepinephrine Arrector pili muscles No effect Stimulates contraction Heart muscle Decreases rate Increase rate and force Coronary blood vessels Constricts Causes vasodilation Bladder/urethra Relax urethral sphincter; Constricts urethral sphincter; promotes voiding inhibits voiding Lungs Constricts bronchioles Dilates bronchioles
  • 11. Target organ/system Parasympatheic effects Sympathetic effects Digestive tract organs Increases peristalsis Decreases glandular acivity and constricts sphincters Liver No effect Releases glucose into blood Gall bladder Stimulates bile secretion Inhibits bile secretion Kidney No effect Decreases urine output; vasoconstriction Penis Causes erection Causes ejaculation Vagina/clitoris Causes erection Reverse peristalsis Blood vessels No effect Constricts blood vessels, increases blood pressure Blood coagulation No effect Increases coagulation Cellular metabolism No effect Increases metabolic rate Adipose tissue No effect Stiulate lipolysis Mental activity No effect Increases altertness
  • 12. Control of autonomic functioning
  • 13. Cortical controls Biofeedback training provides an awareness of visceral activities, enabling an element of voluntary control over autonomic body functions.