The document provides targeted review metrics for March, April, and May including the number of targeted review jobs, percentage of total jobs that were targeted reviews, targeted review jobs by page length and product. It estimates the time savings in hours from targeted reviews for legal, medical, regulatory, and originators based on reduced meeting time from fewer jobs requiring full committee review. In May, 92 jobs underwent targeted review, accounting for 46% of total jobs, and an estimated 48 hours of meeting time was saved across functions.

1. Reviewer Page Range March April May
Jobs % TR Jobs % TR Jobs % TR 1‐10 64 24 55
Giampiccolo (Leg) 41 57% 14 32% 25 27% 11‐25 5 13 24
Civile (Reg) 3 4% 1 2% 4 4% 26‐45 1 7 8
Ameer (Med) 26 36% 22 50% 13 14% 46‐100 1 0 3
Rak (Med) 2 3% 2 5% 40 43% 100+ 1 0 2
Robinett (Reg) 4 9% 8 9%
Parker (Reg) 1 2% 1 1%
Martin (Leg) 1 1% 15
Total TR Jobs 72 100% 44 100% 92 100% 92
6
4
March* April May Hrs. Saved in Meeting Time 24 hrs
FC jobs 73 98 110 March April May
TR jobs
72 44 92
Apidra
4 1 2
TOTAL 145 142 202 Lantus 68 43 89
% Targeted
50% 31% 46%
iBGStar
1
# jobs not
reviewed
Savings in
Hrs.
Legal 66 16.5
Medical
39 9.75
Regulatory 86 21.5
Originators* 92 23
March April May * Time saved by not attending RC
Approved 51 16 45
AWC 4 9 27
Rework 6 0 3
FC 4 0 15
Not completed 7 19 11
TOTALS 72 44 101
May Targeted Review Metrics
Estimated May Meeting Time Savings
Avg NEW jobs on Agenda
TR Jobs Reviewed by Individual Reviewer TR Jobs by Number of Pages
March April May
* numbers are less than actual since Apidra
jobs going FC were not captured for March
TR Reviewer Disposition
% TR Jobs = TR/(FC+TR)
Estimated Savings by Function in
Hrs. Based on a Conservative
Estimate of Review Time per Job
# TR Jobs May
# meetings to cover
Avg. Meeting Time in Hrs.
TR Jobs by Product