DOSAGE FORM, BENTUK SEDIAAN OBAT

1. PHARMACOTHERAPY
Learning outcome :
• Be able to choose drugs for the patients rationally
• ( based on efficacy, safety, acceptability, cost
effectiveness )
Learning objective :
• Be able to select drug dosage forms according to
patient
• Be able to decide drug dose regimens to the patient
• To consider about drug interaction and adverse drug
reactions
• Demonstrate the ability to do the rational drug
prescribing

2. DRUGS DOSE
• MINIMAL DOSE: minimal amount of drug which still give
therapeutic effect
• THERAPEUTIC DOSE / USUAL DOSE : amount of drug
which can give therapeutic effect
• MAXIMAL DOSE : a maximal amount of drug which still
safe be given without acute toxicity symptom
• TOXIC DOSE : amount of drug which give toxicity
symptom
• LETHAL DOSE : amount of drug that can kill some of
animal laboratory. LD50 mean 50 % animal lab.was kill
• FATAL DOSE : amount of drug that can kill a person

3. THE PRESCRIPTION
• Request from doctor to pharmacist prepare the drug which
finally passed to patient.
• An order written by a physician, dentist, veterinarian,
directing to pharmacist to compound and dispense
medication for a patient
The part of prescription
1. Inscriptio  dr. identify, town, date, R/
2. Ordinatio/Praescriptio  name, form,
quantity
3. Signatura  how to use, patient identify
4. Subscriptio  dr. sign

4. EXAMPLE OF PRESCRIPTION
Dr.Iwan Dps May 07
Lissence
Address
R/ Amoxicillin 250 mg caps no.XV
S.3 d.d.caps I
==== sign
Pro : Amin ( dewasa )
Add: jl. Gorris 1 Dps

5. Pulvis : R/ Herocyn powder fl. no. I
S.u.e.
=====sign
Pulveres : R/ Amoxicillin mg 125
Paracetamol mg 200
M. f. pulv. dtd. no. XV
S. 3 d.d.pulv. I
====== sign

6. Tablet : R/ Antalgin 500 mg tab. No. XV
S. 3 d.d. tab. I
======
Capsul : R/ Tetracyclin 250 mg Caps. No.XX
S. 4 d.d.Caps I
======
Suppositoria: R/ Anusol Suppos. No.V
S.1d.d.I intra anus
=====
Syrup : R/ Panadol Syr. fl. No. I
S. 3 d.d. Cth. I
=====
Drop / Guttae : R/ Colme eye drop fl.No. I
S. 4 d.d.gtt. I
=====
Solution : R/ Betadine sol.fl. No. I
S.u. e.
=======

7. Ointment : R/ Terracortryl oint tube no. I
S. u. e.
=====
Cream : R / Counterpain cream tube no I
S.u.e.
=====
Parenteral : R/ Adrenalin inj. ampul no. X
S i.m.m.
=====
R/ Xylomidon vial no. II
S. i. m.m.
======
R/ Dextrose infus fl.no. I
S.i.m.m.
=====

8. S.u.e.=Signa usus externus=tandailah untuk
pemakaian luar
S.3 d.d.= Signa ter de die=tandailah 3 x
sehari
d.t.d.=da tales dosis= masing-masing
dosisnya seperti diatas
fl. = flash= botol kecil
T H A N K Y O U

9. Contoh Form Resep (Goth,1978) :
Nama Dokter
Alamat Rumah
Alamat Praktek
SIP
Tanggal Kota ,tanggal
Superscriptio R/
Inscriptio/Pr
escriptio
Subscriptio
R.Cardinale
R.Adjuvan
Corrigen rasa,
bau, warna
Vehiculum
Perintah
pembuatan
m f l a------
Dosis
(mg,ml)
Dosis
(mg,ml)
Jumlah obat
Signatura S.Aturan pemakaian obat
Paraf/tanda tangan
Nama pasien
Alamat